Platosin Injection 10 mg 1 Vial


Manufactured by:
Active Pharmaceutical Ingredient:
Drug Strength: 10 mg
Drug Form : Injection
Pack Size : 1 vial
Does this requires a prescription ?Yes

Platosin Injection contains Cisplatin | belongs to Alkylating agent

SKU: pg_18524_25616 Categories: ,

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    How it works

    Platosin Injection 10 mg 1 Vial works by stopping the growth of cancer cells by inhibiting the DNA synthesis.

    Side effects

    Major & minor side effects for Platosin Injection 10 mg 1 Vial

    • Pain at the injection site severe
    • Lower back pain severe
    • Fever or chills severe
    • Joint pain
    • Ringing or buzzing in the ears
    • Swelling of feet and lower legs
    • Loss of taste
    • Convulsions (seizures)
    • Sour mouth

    Uses of Platosin Injection 10 mg 1 Vial

    What is it prescribed for?

    • Testicular Cancer

      Cisplatin is used in the treatment of cancer of testicles, which produce the male sex hormones and sperm.

    • Ovarian Cancer

      Cisplatin is used in the treatment of cancer that affects the ovaries.

    • Bladder cancer

      Cisplatin is used in the treatment of bladder cancer, which is an organ that stores urine.


    Frequently asked questions

    • Onset of action

      The peak effect of this medicine can be observed immediately after intravenous injection.

    • Duration of Effect

      The effect of this medicine lasts for an average duration of 24 hours.

    • Safe with Alchohol?

      Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Usage in pregnancy?

      This medicine is not recommended for pregnant women.

    • Usage while breast-feeding?

      This medicine is not recommended in breastfeeding women.

    When not to use?

    • Allergy

      Not recommended in patients with known allergy to Cisplatin or other platinum-containing compounds.

    • Impaired kidney function

      Not recommended in patients with existing kidney impairment.


    Warnings for special population
    • Pregnancy

      This medicine is not recommended for pregnant women.

    • Breast-feeding

      This medicine is not recommended in breastfeeding women.

    General Warnings
    • Impaired kidney function

      This medicine may cause severe kidney injury. The risk may increase if taken with aminoglycoside antibiotics. Close monitoring of serum creatinine, urea, and sodium levels is necessary. Do not administer this medicine more than once every 3 to 4 weeks.

    • Hearing impairment

      This medicine may cause the hearing problem which is more common in children. Audiometric testing should be performed before initiating the treatment and also before every dose. Any symptoms of the hearing problem should be reported to the doctor.

    • Allergy

      This medicine may cause serious skin reactions. Discontinue the treatment if any symptoms of allergy appear and do not restart.

    • Blood cell count

      This medicine may lower the white blood cells and platelets. Close monitoring of blood cell count is necessary. Do not start the treatment if the cell count is low.

    • Infections

      The chances of occurring infections are more in patients receiving this medicine. Hold the chemotherapy and start with the broad-spectrum antibiotics if there are any signs and symptoms of fever. Close monitoring of the body temperature and the blood cell count is necessary.


    • Missed Dose

      It is advised not to miss any dose. If you missed any dose, you should contact your doctor immediately.

    • Overdose

      Seek emergency medical treatment or contact the doctor in case of an overdose.


    Interaction with Medicines
    • Clozapine severe
    • Vancomycin moderate
    • Atorvastatin moderate
    • Live vaccines severe

    General Instructions

    This medicine is given in multiple cycles. It is important to receive the every scheduled dose and make a note of next scheduled dose. Close monitoring of blood cells counts and kidney function.

    Other details

    • Usage does not depend on food timings
    • To be taken as instructed by doctor
    • May cause sleepiness


    Additional Information>

    How to use Platosin Injection 10 mg 1 Vial

    IV: Pretreatment hydration with 1-2 Litre of fluid is recommended prior to cisplatin administration, adequate hydration and urinary output (gt;100 mL/hour). Should be maintained for 24 hours after administration. Aluminium containing IV infusion sets and needles should not be used due to binding with platinum. Rate of administration has varied from a 15 to 120 mins infusion, 1 mg/min infusion, 6-8 hour infusion, 24 hour infusion or per protocol. Maximum rate of infusion: 1 mg/min in patients with CHF. When administered as sequential infusions, taxane derivatives (docetaxel, paclitaxel) should be administered before platinum derivatives to limit myelosuppression and to enhance efficacy.
    Standard IV dilution: Dose 250-1000 mL NS, D5/NS or D5/0.45% NaCl; stable for 72 hours at 4°C to 25°C (in combination with mannitol).
    Compatibility: Stable in D5¼NS, D5½NS, D5NS, ¼NS, 1/3NS, ½NS, NS; incompatible with sodium bicarbonate 5%.

    what are the adverse effects of Platosin Injection 10 mg 1 Vial?

    Nausea, vomiting, diarrhoea, renal impairment, leucopenia, thrombocytopenia, anaemia, aneilema, tinnitus, hearing loss, anaphylactic reactions (e.g. drug eruption); elevated GOT, GPT, ALP; malaise, dizziness, calvities, flush, oedema.

    What happens if I miss a dose of Platosin Injection 10 mg 1 Vial?

    Metastatic testicular tumours: Adults: 20 mg/m² daily for 5 consecutive days (days 1 to 5) every 3rd wk for 4 courses. 30 units of bleomycin on the 2nd day of each wk for 12 consecutive doses. 0.2 mg/kg body weight of vinblastine on days 1 and 2 of every 3rd wk four courses.
    Metastatic ovarian tumours: Once every 3 wk 50 mg/m² and 500 mg/m² of cyclophosphamide. As a single agent: 100 mg/m² by intravenous route every 4th wk.

    One of the following licensed pharmacy from the nearest location will deliver Platosin Injection 10 mg 1 Vial. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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