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PM tablet 500 mg 20x10's

PM tablet contains Paracetamol | belongs to Para-aminophenol derivative

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How it works

PM tablet 500 mg 20×10’s increases the pain threshold and decreases swelling. It also brings down elevated body temperature by acting on heat regulatory centers in the brain.

Side effects

Major & minor side effects for PM tablet 500 mg 20×10’s

  • Nausea or Vomiting
  • Gastric / Mouth Ulcer
  • Anemia
  • Fatigue
  • Stevens-Johnson Syndrome severe

Uses of PM tablet 500 mg 20×10’s

What is it prescribed for?

  • Fever

    PM tablet 500 mg 20×10’s is used to provide temporary relief from fever without treating the underlying cause.

  • Headache

    PM tablet 500 mg 20×10’s is used to relieve acute headaches including a migraine.

  • Muscle Pain

    PM tablet 500 mg 20×10’s is used to relieve mild to moderate pain in the muscles.

  • Menstrual Cramps

    PM tablet 500 mg 20×10’s is used to relieve pain and cramping associated with menstrual cycles in women.

  • Post Immunization Pyrexia

    PM tablet 500 mg 20×10’s is used in the treatment of pain and fever that sets in after one has taken vaccinations.

  • Arthritis

    PM tablet 500 mg 20×10’s is used to relieve joint pain including mild to moderate pain in arthritis.

Concerns

Frequently asked questions

  • Onset of action

    The effect of this medicine can be observed within 1 hour of oral administration. When given in the form of an intravenous injection, the pain-relieving action starts in 5-10 minutes. For fever reduction, the time taken is about 30 minutes.

  • Duration of Effect

    The effect of this medicine lasts for an average duration of 4-6 hours.

  • Safe with Alchohol?

    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, rashes, nausea, joint pain, fever, jaundice, etc.

  • Is it habit forming?

    No habit-forming tendencies were reported.

  • Usage in pregnancy?

    This medicine is not recommended for use in pregnant women unless necessary and the potential benefits outweigh the risks involved. This medicine is not known to cause any harm to the fetus, but should only be used after consultation with your doctor. Oral administration of the medicine should be preferred over the intravenous route.

  • Usage while breast-feeding?

    This medicine is safe to use during breastfeeding. It is advised to consult your doctor before taking this medicine. Monitor the infant for any undesired side effects and report any incidence of rashes on skin or diarrhea in the infant to the doctor immediately.

When not to use?

  • Allergy

    This medicine is not recommended for use if you have a known allergy to PM tablet 500 mg 20×10’s or any other components present along with it.

  • Analgesic Nephropathy (Kidney Disease)

    This medicine is not recommended for use in patients suffering from kidney diseases associated with the excessive use of painkillers.

  • Severe liver impairment

    This medicine is not recommended for use in patients with severe liver diseases due to the increased risk of worsening of the patient's condition.

Warnings

Warnings for special population
  • Pregnancy

    This medicine is not recommended for use in pregnant women unless necessary and the potential benefits outweigh the risks involved. This medicine is not known to cause any harm to the fetus, but should only be used after consultation with your doctor. Oral administration of the medicine should be preferred over the intravenous route.

  • Breast-feeding

    This medicine is safe to use during breastfeeding. It is advised to consult your doctor before taking this medicine. Monitor the infant for any undesired side effects and report any incidence of rashes on skin or diarrhea in the infant to the doctor immediately.

Warnings

Warnings for special population
  • Overdose

    This medicine is available in the market in various dosage forms. Read the label carefully before consuming this medicine to avoid overdosage. Overdose may result in liver damage. Seek emergency medical attention if an overdose of this medicine is suspected.

  • Liver Disease

    This medicine should be used with extreme caution in patients suffering from liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

  • Chronic Malnutrition

    This medicine should be used with extreme caution in patients suffering from malnourishment due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Dosage

  • Missed Dose

    Oral and rectal forms: Since PM tablet 500 mg 20×10’s is administered as an when required, the likelihood of missing a dose is very low. If you are on a scheduled dosing regimen of this medicine, the missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not double the dose to make up for the missed one. Since PM tablet 500 mg 20×10’s injection is usually administered by a qualified healthcare professional in a clinical or hospital setting, the likelihood of missing a dose is very low.

  • Overdose

    Oral and rectal forms: Seek emergency medical attention or contact your doctor in case of an overdose with PM tablet 500 mg 20×10’s. Injection: Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

Interactions

Interaction with Medicines
  • Carbamazepine moderate
  • Phenytoin moderate
  • Sodium Nitrite severe
  • Leflunomide severe
  • Prilocaine severe
Disease interactions
  • severe

    This medicine should be used with extreme caution in patients with chronic alcohol use due to the increased risk of serious liver injuries. Close monitoring of liver function is recommended for such patients. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

  • severe

    This medicine should be used with extreme caution in patients with liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Report any symptoms such as nausea, fever, rashes, dark urine, etc. to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Lab interactions

General Instructions

Oral forms: Take PM tablet 500 mg 20×10’s as advised by your doctor. You may take this medicine with or without food. Do not take in larger amounts than advised. Usage should never exceed the recommended daily maximum dosage limit of 4 grams in a 24-hour time period. Rectal forms: Use PM tablet 500 mg 20×10’s exactly as advised by your doctor. Do not take in larger or smaller quantities than advised. Injection: PM tablet 500 mg 20×10’s should be administered by a trained healthcare professional as per the doctor's instructions. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.

Other details

  • Can be taken with or without food, as advised by your doctor
  • To be taken as instructed by doctor
  • Does not cause sleepiness

References

How to use PM tablet 500 mg 20×10’s

IV Inj 10 mg/mL: By IV infusion over 15 min.
Stability: Store intact vial at room temperature 20°C-25°C. Do not refrigerate or freeze. Use within 6 hours of opening vial or transferring to another container.

UNLICENSED USE
Children: Not recommended for use of oral dosage form under 2 mth; rectal dosage form under 3 mth; IV infusion in preterm neonates. Max 4 doses/24 hr.
ORAL: Pain; pyrexia with discomfort: Neonate 28-32 wk corrected gestational age, 20 mg/kg as a single dose then 10-15 mg/kg every 8-12 hr as necessary, max 30 mg/kg/day in divided doses. Neonate over 32 wk corrected gestational age, 20 mg/kg as a single dose then 10-15 mg/kg every 6-8 hr as necessary, max 60 mg/kg/day in divided doses; 1-2 mth, 30-60 mg every 8 hr as necessary, max 60 mg/kg daily in divided doses.
RECTAL: Pain; pyrexia with discomfort: Neonate 28-32 wk corrected gestational age, 20 mg/kg as a single dose then 10-15 mg/kg every 12 hr as necessary; max. 30 mg/kg daily in divided doses; Neonate over 32 wk corrected gestational age, 30 mg/kg as a single dose then 15-20 mg/kg every 8 hr as necessary, max. 60 mg/kg/day in divided doses; 1-3 mth, 30-60 mg every 8 hr as necessary, max 60 mg/kg/day in divided doses.
Postoperative pain: 1-3 mth, 30 mg/kg as a single dose then 15-20 mg/kg every 4-6 hrs, max 75 mg/kg/day in divided doses.
INJECTION: IV infusion over 15 min. Pain; pyrexia with discomfort: Preterm neonate over 32 wk corrected gestational age, 7.5 mg/kg every 8 hr, max 25 mg/kg/day.

what are the adverse effects of PM tablet 500 mg 20×10’s

Cyanosis, skin eruptions, hypoglycaemia, CNS stimulations. Inj: Hypotension, flushing and tachycardia.

What is the dose of PM tablet 500 mg 20×10’s

Adults: ORAL: Repeat every four hr if necessary up to max 4 doses in 24 hr. Single dose of 500 mg to 1000 mg which may be repeated every 4 hr, max 4000 mg/day.
RECTAL: 500-1000 mg every 4-6 hr, max 4 gm/day.
INJECTION: 1 amp (2 mL) IM 6 hourly. IV infusion over 15 min: Over 50 kg body-weight, 1 gm every 4-6 hr, max 4 gm daily.
Children: Not recommended for use of oral dosage form under 2 mth; rectal dosage form under 3 mth; IV infusion in preterm neonates.
ORAL: Pain; pyrexia with discomfort: 2-3 mth, 30-60 mg every 8 hr as necessary, max 60 mg/kg daily in divided doses; 3-6 mth, 60 mg every 4-6 hr, max 4 doses/day; 6 mth-2 yr, 120 mg every 4-6 hr, max 4 doses/day; 2-4 yr, 180 mg every 4-6 hr, max 4 doses/day; 4-6 yr, 240 mg every 4-6 hr, max 4 doses/day; 6-8 yr, 240-250 mg every 4-6 hr, max 4 doses/day; 8-10 yr, 360-375 mg every 4-6 hr, max 4 doses/day; 10-12 yr, 480-500 mg every 4-6 hr, max 4 doses/day; 12-16 yr, 480-750 mg every 4-6 hr, max 4 doses/day; 16-18 yr, 500 mg-1 gm every 4-6 hr, max 4 doses/day.
RECTAL: Pain; pyrexia with discomfort: 3-12 mth, 60-125 mg every 4-6 hr as necessary, max 4 doses/day; 1-5 yr, 125-250 mg every 4-6 hr as necessary, max 4 doses/day; 5-12 yr, 250-500 mg every 4-6 hr as necessary, max 4 doses/day; 12-18 yr, 500 mg every 4-6 hr.
Postoperative pain: 1-3 mth, 30 mg/kg as a single dose then 15-20 mg/kg every 4-6 hr, max 75 mg/kg/day in divided doses; 3 mth-6 yr, 30-40 mg/kg as a single dose then 15-20 mg/kg every 4-6 hr, max 75 mg/kg daily in divided doses; 6-12 yr, 30-40 mg/kg, (max 1 gm) as a single dose then 15-20 mg/kg every 4-6 hr, max 75 mg/kg (max 4 g) daily in divided doses; 12-18 yr, 1 gm every 4-6 hr, max 4 doses/day.
INJECTION: IV infusion over 15 min. Pain; pyrexia with discomfort: Neonate, 10 mg/kg every 4-6 hr, max 30 mg/kg/day; child body-weight under 10 kg, 10 mg/kg every 4-6 hr, max 30 mg/kg/day; child body-weight 10-50 kg, 15 mg/kg every 4-6 hr, max 60 mg/kg/day; child body-weight over 50 kg, 1 gm every 4-6 hr, max 4 gm daily.

One of the following licensed pharmacy from the nearest location will deliver PM tablet 500 mg 20×10’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts the your request based on valid prescription and availability.

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