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Prasugrel Hydrochloride 5mg (Effient)

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Alternate brands of Prasugrel Hydrochloride 5mg (Effient)

Brand Name Price Savings
Persiva tablet 5 mg 14’s  118.00 You will pay -118 more
Natuzzi tablet 10 mg 20’s  280.00 You will pay -280 more
Eficlot tablet 5 mg 14’s  118.00 You will pay -118 more
Eficlot tablet 10 mg 14’s  196.00 You will pay -196 more
List of alternate brands

Effient, a formulation of Prasugrel Hydrochloride, is a medication used to prevent blood clots in patients with acute coronary syndrome who are undergoing percutaneous coronary intervention (PCI). Each tablet contains 5mg of Prasugrel, an antiplatelet agent that helps reduce the risk of cardiovascular events such as heart attacks and strokes.

How It Works

Prasugrel Hydrochloride works by inhibiting platelet aggregation. Platelets are small blood cells that clump together to form clots. Prasugrel is a prodrug that, once metabolized in the liver, irreversibly inhibits the P2Y12 ADP-mediated platelet receptor, thereby preventing ADP from binding to its platelet receptor and subsequent platelet activation and aggregation. This action reduces the likelihood of clots forming in arteries, which is critical in preventing heart attacks and other thrombotic cardiovascular events.

Side Effects

  • Bleeding (including gastrointestinal and intracranial bleeding)
  • Hematoma
  • Thrombocytopenia (low platelet count)
  • Hypertension
  • Headache
  • Fatigue
  • Nausea
  • Dizziness
  • Rash
  • Dyspnea (shortness of breath)

Indications

  • Reduction of thrombotic cardiovascular events in patients with acute coronary syndrome (ACS) who are managed with percutaneous coronary intervention (PCI)
  • Patients with unstable angina or non-ST-elevation myocardial infarction (NSTEMI)
  • Patients with ST-elevation myocardial infarction (STEMI) when managed with primary or delayed PCI

Contraindications

  • Active pathological bleeding (e.g., peptic ulcer or intracranial hemorrhage)
  • History of transient ischemic attack (TIA) or stroke
  • Severe hepatic impairment
  • Hypersensitivity to Prasugrel or any component of the product
  • Patients over 75 years of age, unless high risk (e.g., diabetes or history of prior myocardial infarction)
  • Body weight less than 60 kg (dose adjustment needed)

Price in Different Countries

Price Comparison of Effient (Prasugrel Hydrochloride 5mg)
Country Price (USD) Source
United States $300 Drugs.com
Canada $250 CanadaDrugs.com
United Kingdom $270 NHS UK
Australia $280 PBS Australia
India $50 1mg.com

Top 5 Global Brands

  1. Effient (Daiichi Sankyo / Eli Lilly)
  2. Prasita (Dr. Reddy’s Laboratories)
  3. Prasugrel Sandoz (Sandoz)
  4. Efient (AstraZeneca)
  5. Prasugrel Teva (Teva Pharmaceuticals)

How it works

Prasugrel Hydrochloride 5mg (Effient) works by blocking platelets from sticking together and prevents them from forming harmful blood clots. This "anti-platelet" effect helps to keep blood flowing smoothly in your body.

Uses of Prasugrel Hydrochloride 5mg (Effient)

What is it prescribed for?

  • Acute Coronary Syndrome

    Prasugrel Hydrochloride 5mg (Effient) is used in the treatment of acute coronary syndrome which is a condition that blocks the blood flow to the heart muscles.

Concerns

Frequently asked questions

  • Onset of action

    The peak effect of this medicine can be observed in 30 minutes.

  • Duration of Effect

    The effect of this medicine lasts for an average duration of 24 hours.

  • Safe with Alchohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    No habit forming tendency has been reported.

  • Usage in pregnancy?

    This medicine is recommended in pregnant women only if necessary. The benefits and risks should be discussed with the doctor before receiving this medicine.

  • Usage while breast-feeding?

    The excretion of this medicine in breast milk is unknown. It is used in pregnant women only if necessary. The benefits and risks should be discussed with the doctor before taking this medicine.

When not to use?

  • Allergy

    Not recommended in patients with known allergy to Prasugrel Hydrochloride 5mg (Effient) .

  • Bleeding

    Not recommended in patients with any bleeding disorder like the peptic ulcer or brain injury.

Warnings

Warnings for special population
  • Pregnancy

    This medicine is recommended in pregnant women only if necessary. The benefits and risks should be discussed with the doctor before receiving this medicine.

  • Breast-feeding

    The excretion of this medicine in breast milk is unknown. It is used in pregnant women only if necessary. The benefits and risks should be discussed with the doctor before taking this medicine.

General Warnings
  • Bleeding disorder

    This medicine may increase the risk of bleeding, therefore should be used with caution in patients with the bleeding disorder. Inform the doctor if you have any gastrointestinal diseases or brain injury. Close monitoring of platelets count is necessary.

  • Allergy

    This medicine is known to cause allergic reactions includes swelling of face, lips, eyelids. The treatment should be discontinued if any symptoms of allergy appear.

Dosage

  • Missed Dose

    The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

  • Overdose

    Seek emergency medical treatment or contact the doctor in case of overdose.

Interactions

Interaction with Medicines
  • Escitalopram moderate
  • Warfarin severe
  • Nonsteroidal anti-inflammatory drugs severe
Disease interactions
  • severe

    This medicine may increase the risk of bleeding, therefore not recommended in patients with the bleeding disorder. Inform the doctor if you have any gastrointestinal diseases or an injury. Close monitoring of platelets count is necessary.

General Instructions

Take Prasugrel Hydrochloride 5mg (Effient) as advised by your doctor. Do not take in larger amounts than advised. It is advised to take this medicine at the same time every day. Inform the doctor if you have any history of peptic ulcer disease or head injury. Do not stop taking this medicine without consulting your doctor.

References

Additional Information:

One of the following licensed pharmacy from the nearest location will deliver Prasugrel Hydrochloride 5mg (Effient). The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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