MBBS
Prasugrel Hydrochloride 5mg (Effient)
Alternate brands of Prasugrel Hydrochloride 5mg (Effient)
| Brand Name | Price | Savings |
|---|---|---|
| Persiva tablet 5 mg 14’s | ₨ 118.00 | You will pay -118 more |
| Natuzzi tablet 10 mg 20’s | ₨ 280.00 | You will pay -280 more |
| Eficlot tablet 5 mg 14’s | ₨ 118.00 | You will pay -118 more |
| Eficlot tablet 10 mg 14’s | ₨ 196.00 | You will pay -196 more |
Effient, a formulation of Prasugrel Hydrochloride, is a medication used to prevent blood clots in patients with acute coronary syndrome who are undergoing percutaneous coronary intervention (PCI). Each tablet contains 5mg of Prasugrel, an antiplatelet agent that helps reduce the risk of cardiovascular events such as heart attacks and strokes.
How It Works
Prasugrel Hydrochloride works by inhibiting platelet aggregation. Platelets are small blood cells that clump together to form clots. Prasugrel is a prodrug that, once metabolized in the liver, irreversibly inhibits the P2Y12 ADP-mediated platelet receptor, thereby preventing ADP from binding to its platelet receptor and subsequent platelet activation and aggregation. This action reduces the likelihood of clots forming in arteries, which is critical in preventing heart attacks and other thrombotic cardiovascular events.
Side Effects
- Bleeding (including gastrointestinal and intracranial bleeding)
- Hematoma
- Thrombocytopenia (low platelet count)
- Hypertension
- Headache
- Fatigue
- Nausea
- Dizziness
- Rash
- Dyspnea (shortness of breath)
Indications
- Reduction of thrombotic cardiovascular events in patients with acute coronary syndrome (ACS) who are managed with percutaneous coronary intervention (PCI)
- Patients with unstable angina or non-ST-elevation myocardial infarction (NSTEMI)
- Patients with ST-elevation myocardial infarction (STEMI) when managed with primary or delayed PCI
Contraindications
- Active pathological bleeding (e.g., peptic ulcer or intracranial hemorrhage)
- History of transient ischemic attack (TIA) or stroke
- Severe hepatic impairment
- Hypersensitivity to Prasugrel or any component of the product
- Patients over 75 years of age, unless high risk (e.g., diabetes or history of prior myocardial infarction)
- Body weight less than 60 kg (dose adjustment needed)
Price in Different Countries
| Country | Price (USD) | Source |
|---|---|---|
| United States | $300 | Drugs.com |
| Canada | $250 | CanadaDrugs.com |
| United Kingdom | $270 | NHS UK |
| Australia | $280 | PBS Australia |
| India | $50 | 1mg.com |
Top 5 Global Brands
- Effient (Daiichi Sankyo / Eli Lilly)
- Prasita (Dr. Reddy’s Laboratories)
- Prasugrel Sandoz (Sandoz)
- Efient (AstraZeneca)
- Prasugrel Teva (Teva Pharmaceuticals)
How it works
Prasugrel Hydrochloride 5mg (Effient) works by blocking platelets from sticking together and prevents them from forming harmful blood clots. This "anti-platelet" effect helps to keep blood flowing smoothly in your body.
Side effects
Major & minor side effects for Prasugrel Hydrochloride 5mg (Effient)
- Blurred vision severe
- Dizziness severe
- Headache severe
- Chest discomfort severe
- Irregular heartbeat severe
- Mouth ulcers severe
- Diarrhea
- Nausea
- Skin rash
- Pain in the arms and legs
Uses of Prasugrel Hydrochloride 5mg (Effient)
What is it prescribed for?
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Acute Coronary Syndrome
Prasugrel Hydrochloride 5mg (Effient) is used in the treatment of acute coronary syndrome which is a condition that blocks the blood flow to the heart muscles.
When not to use?
-
Allergy
Not recommended in patients with known allergy to Prasugrel Hydrochloride 5mg (Effient) .
-
Bleeding
Not recommended in patients with any bleeding disorder like the peptic ulcer or brain injury.
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Bleeding disorder
This medicine may increase the risk of bleeding, therefore should be used with caution in patients with the bleeding disorder. Inform the doctor if you have any gastrointestinal diseases or brain injury. Close monitoring of platelets count is necessary.
-
Allergy
This medicine is known to cause allergic reactions includes swelling of face, lips, eyelids. The treatment should be discontinued if any symptoms of allergy appear.
Dosage
-
Missed Dose
The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.
-
Overdose
Seek emergency medical treatment or contact the doctor in case of overdose.
-
severe
This medicine may increase the risk of bleeding, therefore not recommended in patients with the bleeding disorder. Inform the doctor if you have any gastrointestinal diseases or an injury. Close monitoring of platelets count is necessary.
General Instructions
Take Prasugrel Hydrochloride 5mg (Effient) as advised by your doctor. Do not take in larger amounts than advised. It is advised to take this medicine at the same time every day. Inform the doctor if you have any history of peptic ulcer disease or head injury. Do not stop taking this medicine without consulting your doctor.
Other details
- Can be taken with or without food, as advised by your doctor
- To be taken as instructed by doctor
- Does not cause sleepiness
References
- webmd.com - Prasugrel [Internet]. Available from: https://www.webmd.com/drugs/2/drug-152680/prasugrel-oral/details [cited 27/7/2020].
One of the following licensed pharmacy from the nearest location will deliver Prasugrel Hydrochloride 5mg (Effient). The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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