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Information on this page was last modified on : 2021/04/30 3:22:42 PM

Quinine Dihydrochloride Injection 100 Ampx1 mL

Belongs to Category

Quinine Dihydrochloride Injection contains Quinine | belongs to 4-Methanolquinolone

Alternate brands of Quinine Dihydrochloride Injection 100 Ampx1 mL

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Zafquin Injection 10 Ampx2 mL  246.86 You can save 590.14
Quinine Injection 100 Ampx1 mL  469.04 You can save 367.96
Quinine Bisulphate tablet 100’s  230.00 You can save 607
Quinine Bisulphate tablet 10×10’s  215.00 You can save 622
Quinine Bisulphate Injection 100 Ampx1 mL  670.59 You can save 166.41
List of alternate brands

How it works

Quinine Dihydrochloride Injection 100 Ampx1 mL works by killing the organisms that cause malaria.

Side effects

Major & minor side effects for Quinine Dihydrochloride Injection 100 Ampx1 mL

  • Severe diarrhea severe
  • Nausea and Vomiting severe
  • Severe abdominal pain severe
  • Black or tarry stools severe
  • Bloody stool severe
  • Blurred vision severe
  • Anxiety and nervousness
  • Difficult and painful breathing severe
  • Severe back pain
  • Ringing or buzzing in the ears severe
  • Swelling of the eyes, ears, and inside of nose severe
  • Slurred speech
  • Sleeplessness
  • Excessive hunger
  • Fast heartbeat severe

Uses of Quinine Dihydrochloride Injection 100 Ampx1 mL

What is it prescribed for?

  • Malaria

    This medicine is used to treat uncomplicated malaria which is resistant to Chloroquine.

Concerns

Frequently asked questions

  • Onset of action

    The time taken for this medicine to show its effect is not known. However, it is readily available when taken orally and reaches the peak levels within 1-4 hours.

  • Duration of Effect

    The time duration for which this medicine remains active in the body is subject to variations based on the patient's condition.

  • Safe with Alchohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    No habit forming tendencies were reported.

  • Usage in pregnancy?

    Use of this medicine in pregnant women is not recommended unless absolutely necessary and the benefits outweigh the risk associated with use. Consult your doctor using this medicine.

  • Usage while breast-feeding?

    Use of this medicine by women who are breastfeeding is not recommended unless necessary. Consult your doctor before using this medicine.

When not to use?

  • Allergy

    This medicine is not recommended for use if you have a known history of allergy to Quinine Dihydrochloride Injection 100 Ampx1 mL or other related antimalarial medicines like mefloquine, quinidine etc.

  • G6PD deficiency

    This medicine is not recommended for use in patients having this rare hereditary condition where the red blood cell function is abnormal.

  • Quinine Dihydrochloride Injection 100 Ampx1 mL associated blackwater fever

    This medicine is not recommended for use in patients having a history of blackwater fever associated with Quinine Dihydrochloride Injection 100 Ampx1 mL use.

  • Myasthenia gravis

    This medicine is not recommended for use in patients suffering from this condition where muscles tire rapidly.

  • Optic neuritis

    This medicine is not recommended for use in patients suffering from this condition where the nerve fibers of the eye are damaged.

Warnings

Warnings for special population
  • Pregnancy

    Use of this medicine in pregnant women is not recommended unless absolutely necessary and the benefits outweigh the risk associated with use. Consult your doctor using this medicine.

  • Breast-feeding

    Use of this medicine by women who are breastfeeding is not recommended unless necessary. Consult your doctor before using this medicine.

General Warnings
  • Antacids

    Report the regular use of medicines taken for reducing acidity. This medicine may interact with acidity regulating medications and may potentially cause side effects.

  • Heart diseases

    Report the incidence of any disease of the heart and blood vessels to the doctor. The risk of adverse effects on the heart is significantly high while using this medicine. This medicine should be used with caution in patients susceptible to heart conditions or are exposed to the risk factors.

  • Nicotine uptake

    This medicine is known to show less effect in people who smoke regularly or use tobacco products in any form. Use of tobacco products should be avoided while taking this medicine.

  • Low blood sugar

    This medicine is known to cause a fall in blood sugar levels upon consumption. Appropriate precautionary measures and a regular check are advised especially if you have diabetes.

  • Surgery

    Report the use of this medicine to the doctor if a surgery is advised. Use of this medicine can cause adverse effects and may interfere with the regular procedure.

  • Off label use

    Use of this medicine for treating or relieving symptoms not associated with malaria is not recommended. Any off-label use of this medicine should be avoided.

Dosage

  • Missed Dose

    Take the missed dose only if you are late by less than four hours. Do not take extra medicine to make up for the missed dose.

  • Overdose

    Contact your doctor immediately if an overdose with this medicine is suspected. Symptoms of an overdose may include nausea, vomiting, headache, abdominal pain, change in the heartbeat, excessive sweating etc.

Interactions

Interaction with Medicines
  • Ketoconazole moderate
  • Amiodarone severe
  • Pimozide severe
  • Quinidine severe
  • Aminophylline moderate
  • Atorvastatin moderate
  • Ritonavir severe
  • Magnesium/Aluminum containing medicines severe
  • Sodium Bicarbonate moderate

General Instructions

Take Quinine Dihydrochloride Injection 100 Ampx1 mL as instructed by the doctor. It is advised to take this medicine for the entire prescribed course even if the symptoms get better. This medicine can be taken with food if gastric irritation is experienced. Contact your doctor if any serious side effects are experienced while taking this medicine.

Other details

  • To be taken with food
  • To be taken as instructed by doctor
  • May cause sleepiness

References

Additional Information:

what are the adverse effects of Quinine Dihydrochloride Injection 100 Ampx1 mL?

Hypersensitivity reactions, blood dyscrasias, acute renal failure, hypoglycaemia cardiovascular effects, cinchonism manifest by tinnitus, headache, nausea, abdominal pain, flushing, rash, visual disturbances, confusion.

What happens if I miss a dose of Quinine Dihydrochloride Injection 100 Ampx1 mL?

ORAL: Adults: Treatment of chloroquine resistant malaria: 650 mg (Quinine sulphate) every 8 hr for 3-7 days with tetracycline. Suppression of malaria: 325 mg (Quinine sulphate) twice daily and continued for 6 wk after exposure.
Children: gt; 8 yr: Treatment of chloroquine resistant malaria: 25-30 mg/kg/day (Quinine sulphate) in divided doses every 8 hr for 3-7 days with tetracycline. Below 8 yr, consider risk versus benefit.
INJECTION: Treatment of Falciparum malaria: Adults: By IV infusion: Loading dose 20 mg/kg (Quinine dihydrochloride or hydrochloride), up to max 1.4 gm infused over 4 hr, then 8 hr after the start of the loading dose; maintenance dose of 10 mg/kg (up to max 700 mg) of quinine salt infused over 4 hr every 8 hr (till patient can swallow tablets to complete the 7 day course together with or followed by doxycycline 200 mg once daily for 7 days).
Treatment of malaria caused by Plasmodium vivax/P. ovale/P. malariae: Adults & Children: By IV infusion: 10 mg/kg (Quinine dihydrochloride or hydrochloride), up to max 700 mg infused over 4 hr, every 8 hr changed to oral chloroquine as soon as patient’s condition permits.

One of the following licensed pharmacy from the nearest location will deliver Quinine Dihydrochloride Injection 100 Ampx1 mL. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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