Rescuvolin tablet 15 mg 10’s

 2,500.00

Manufactured by:
Active Pharmaceutical Ingredient:
Drug Strength: 15 mg
Drug Form : Tablet
Pack Size : 10s
Does this requires a prescription ?Yes

Rescuvolin tablet contains Calcium Leucovorin | belongs to Antidote to folic acid antagonist

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    How it works

    Rescuvolin tablet 15 mg 10’s works by protecting healthy cells from the effects of methotrexate or similar medications while allowing methotrexate to enter and kill cancer cells.

    Side effects

    Major & minor side effects for Rescuvolin tablet 15 mg 10’s

    • Severe skin rash and hives severe
    • Swelling of the face, arms, hands, lower legs, or feet severe
    • Difficulty in breathing severe
    • Difficulty in swallowing severe
    • Fainting severe
    • Fever severe
    • Convulsions (seizures) severe
    • Agitation and anxiety rare
    • Indigestion
    • Difficulty in falling asleep
    • Peeling and blistering of skin severe
    • Constipation
    • Unusual tiredness or weakness rare

    Uses of Rescuvolin tablet 15 mg 10’s

    What is it prescribed for?

    • Methotrexate rescue

      This medicine is used to reduce the toxicity caused due to the administration of methotrexate. It is also used to counteract the effects of an impaired methotrexate elimination or accidental overdosage.

    • Folic acid antagonist overdose

      This medicine is also used to replenish folic acid in the body and reduce the toxicity caused due to the administration of folic acid antagonists such as aminopterin, pyrimethamine, trimethoprim, triamterene, etc. It is also used to counteract the toxic effects caused due to an accidental overdose of these medicines.

    • Megaloblastic Anemia

      This medicine is used to treat megaloblastic anemia, a type of anemia with a lower than the normal number of red blood cells, caused by a deficiency of folic acid due to malnourishment, liver disease, pregnancy, or a reduced ability to absorb folic acid from the diet.

    • Colorectal Cancer

      This medicine is used along with 5-Fluorouracil to prolong survival of the patients suffering from advanced colorectal cancer.

    Concerns

    Frequently asked questions

    • Onset of action

      The effect of oral forms of this medicine can be observed within 20 to 30 minutes. The effect of an intravenous administration can be observed within 5 minutes and the effect of an intramuscular administration can be observed within 10 to 20 minutes.

    • Duration of Effect

      The effect of this medicine lasts for an average duration of 3 to 6 hours.

    • Safe with Alchohol?

      Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

    • Is it habit forming?

      No habit-forming tendencies were reported.

    • Usage in pregnancy?

      This medicine is not recommended for use in pregnant women unless absolutely necessary. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine.

    • Usage while breast-feeding?

      This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before beginning therapy with this medicine.

    When not to use?

    • Allergy

      This medicine is not recommended for use in patients with a known allergy to leucovorin/calcium folinate or any other inactive ingredients present in the formulation.

    • Pernicious anemia

      This medicine is not recommended for use in patients suffering from an anemia caused due to the deficiency of vitamin B12.

    Warnings

    Warnings for special population
    • Pregnancy

      This medicine is not recommended for use in pregnant women unless absolutely necessary. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine.

    • Breast-feeding

      This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before beginning therapy with this medicine.

    General Warnings
    • Other medicines

      This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you report all your current medicines, including any herbs and supplements, to the doctor before beginning treatment with this medicine.

    • Use in elderly

      This medicine should be used with caution in the elderly patients since the risk of adverse effects is significantly high. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the patient's condition.

    • Seizure disorders

      This medicine should be used with caution in patients with an active seizure disorder since it may worsen the patient's condition. This risk is especially higher if higher doses of this medicine are used. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the patient's clinical condition.

    • Serious allergic reactions

      Use of this medicine may cause severe or life-threatening allergic reactions in some patients. This risk is especially higher when this medicine is used as a part of a combination therapy. Report any unusual symptoms such as increased sweating, difficulty breathing, itching, chills, etc. to your doctor immediately. Appropriate corrective measures and replacement with a suitable alternative may be necessary based on the patient's condition.

    • Form of medicine and dosing schedule

      The dosing schedule and form of administration are likely to vary based on the condition being treated and co-administration of other medicines along with leucovorin. Do not change the dose or schedule of uptake of this medicine without consulting your doctor.

    • Gastrointestinal toxicities

      The combination therapy of 5-fluorouracil and this medicine should be used with caution due to the increased risk of gastrointestinal toxicities. These toxicities may include swelling of the gastrointestinal tract walls and diarrhea. This risk is especially higher if the combination therapy is used for a prolonged period of time. Therapy should not be initiated or continued in such patients unless symptoms of toxicity are completely resolved.

    Dosage

    • Missed Dose

      Oral forms: Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose, then the missed dose can be skipped. Do not use extra medicine to make up for the missed dose. Injectable forms: Since this medicine is usually administered in a clinical/hospital setting, the likelihood of missing a dose is very low. If you miss a scheduled appointment for a dose of this medicine, contact your doctor for further instructions.

    • Overdose

      Oral forms: Seek emergency medical treatment or contact the doctor in case of an overdose. Injectable forms: Since this medicine is usually administered in a clinic/hospital, the likelihood of an overdose is very low. However, emergency medical treatment will be instituted by the doctor if an overdose is suspected.

    Interactions

    Interaction with Medicines
    • Phenobarbital moderate
    • Fluorouracil severe
    • Capecitabine severe
    • Trimethoprim severe
    • Ceftriaxone severe
    • Phenytoin moderate
    • Methotrexate moderate
    Disease interactions
    • severe

      This medicine should not be used to treat an undiagnosed anemia. It should not be used if the anemia is caused by a deficiency of vitamin B12 since it may worsen the patient's condition.

    • severe

      This medicine should be used with extreme caution in patients with a history of seizure disorders since it may worsen the patient's condition. This risk is especially higher if higher doses of this medicine are used. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

    General Instructions

    Oral forms: Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor. Injectable forms: This medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting. Follow all the instructions given by your doctor. Report to the doctor if you have a known allergy to this medicine. Report all your current medicines, including any herbs and supplements, and your medical conditions to the doctor before receiving treatment with this medicine.

    Other details

    • Usage does not depend on food timings
    • To be taken as instructed by doctor
    • May cause sleepiness

    References

    Additional Information>

    What happens if I miss a dose of Rescuvolin tablet 15 mg 10’s?

    Antidote: To be adjusted to individual needs, provided that it corresponds to approximately 10 to 20 per cent of the methotrexate dose. See literature.
    Megaloblastic anaemias: Treatment, initial course of 10 mg daily for 10 to 15 days, but 1 mg daily is probably adequate, subsequent therapy and dosage modified to the haematological response.

    One of the following licensed pharmacy from the nearest location will deliver Rescuvolin tablet 15 mg 10’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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