Sandostatin Injection 0.1 mg 5 Amp
Sandostatin Injection contains Octreotide Acetate | belongs to Somatostatin analogue
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How to use Sandostatin Injection 0.1 mg 5 Amp
IM: Depot formulation: Administer immediately after reconstitution, administered in gluteal muscle. Avoid deltoid administration. IV: Regular injection only. IV administration may be IVP, IVPB or continuous infusion. IVP should be administered undiluted over 3 min. IVPB should be administered over 15-30 min. Continuous IV infusion rates have ranged from 25-50 mcg/hour for the treatment of esophageal variceal bleeding.
Compatibility: Stable in D5W, NS. Incompatible with fat emulsion 10%.
Stability: Should be stored under refrigeration. Ampoules may be stored at room temperature for up to 14 days when protected from light. Stability of parenteral admixture in NS at room temperature (25°C) and at refrigeration temperature (4°C) is 48 hours.
what are the adverse effects of Sandostatin Injection 0.1 mg 5 Amp?
Inj site reaction. GI disturbances. Gallstones, biliary colic. Rarely, persistent hyperglycaemia, hypoglycaemia, hair loss, hepatic dysfunction, acute pancreatitis.
What happens if I miss a dose of Sandostatin Injection 0.1 mg 5 Amp?
Sandostatin Inj 0.05 mg/0.1 mg: GEP tumours: Adults: Initially 0.05 mg once or twice daily by SC Inj increasing to 0.2 mg three times daily if necessary.
Carcinoid crises: Adults: 0.05 mg by IV Inj diluted with saline and given as a bolus; see literature.
Pancreatic surgery: Adults: 0.1 mg thrice daily by SC Inj for 7 days, starting 1 hr before laparotomy. Children: Not recommended.
Acromegaly: Adults: 0.1-0.2 mg three times daily by SC Inj. Children: Not recommended.
Sandostatin LAR Inj: GEP tumours, Carcinoid crises: Adults: After control has been established with subcutaneous Sandostatin, administer 20 mg of Sandostatin LAR by deep intragluteal inj every 4 wk for 3 mth. Continue with same dose of subcutaneous Sandostatin for 2 wk after starting Sandostatin LAR. Reassess after 3 mth, adjust subsequent doses according to response. See literature.
Acromegaly: When control established initially 20 mg of Sandostatin LAR by deep intragluteal inj every 4 wk for 3 mth. Adjust subsequent doses according to levels of GH or IGF-I and clinical response. Children: Not recommended.
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