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Shingrix Vaccine Herpes Zoster Vaccine

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How it Works

Shingrix is a recombinant, adjuvanted vaccine designed to prevent herpes zoster (shingles). Shingles is caused by the reactivation of the varicella-zoster virus (VZV), the same virus that causes chickenpox. Shingrix contains a glycoprotein E (gE) antigen, which is a component of the VZV virus. When administered, the vaccine stimulates the immune system to produce a strong, targeted immune response against the gE antigen. This response helps prevent the reactivation of the VZV in the body, thereby reducing the risk of developing shingles and its associated complications, such as postherpetic neuralgia (PHN). The adjuvant system in Shingrix, AS01B, enhances the body’s immune response to the antigen.

Side Effects

  • Pain at the injection site
  • Redness and swelling at the injection site
  • Myalgia (muscle pain)
  • Fatigue
  • Headache
  • Shivering
  • Fever
  • Gastrointestinal symptoms (e.g., nausea, vomiting, diarrhea)
  • Generalized weakness
  • Joint pain


  • Prevention of herpes zoster (shingles) in adults aged 50 years and older
  • Prevention of herpes zoster in adults aged 18 years and older who are at increased risk due to immunodeficiency or immunosuppression caused by known disease or therapy


  • Hypersensitivity to any component of the vaccine, including gE antigen or AS01B adjuvant
  • Individuals with a history of severe allergic reactions (e.g., anaphylaxis) to any component of the vaccine
  • Pregnancy (use only if clearly needed and benefits outweigh the risks)
  • Severe immunodeficiency (e.g., primary or acquired immunodeficiency)

Price Comparison in Different Countries

Country Price (USD) Website
United States $150 per dose GoodRx
Canada $190 per dose PharmacyChecker
United Kingdom £160 per dose NHS
Australia AUD 280 per dose PBS
India ₹10,000 per dose Medindia

Top 5 Global Brands

  1. Shingrix (GlaxoSmithKline)
  2. Zostavax (Merck & Co.)
  3. Varivax (Merck & Co.)
  4. ProQuad (Merck & Co.)
  5. Varilrix (GlaxoSmithKline)


Additional Information:

One of the following licensed pharmacy from the nearest location will deliver Shingrix Vaccine Herpes Zoster Vaccine. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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