SIM-EZEE 10mg Tablet 10s

Frequently asked questions

• Onset of action

  The amount of time required for this medicine to show its action is not clinically established.

• Duration of Effect

  The amount of time for which this medicine remains active in the body is not clinically established.

• Safe with Alchohol?

  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

• Is it habit forming?

  No habit-forming tendencies were reported.

• Usage in pregnancy?

  This medicine is not recommended for use in pregnant women due to the increased risk of fetal harm. Your doctor may prescribe a safer alternative based on your clinical condition.

• Usage while breast-feeding?

  This medicine is not recommended for use in breastfeeding women. Your doctor may prescribe a safer alternative based on your clinical condition.

• Allergy

  This medicine is not recommended for use in patients with a known allergy to simvastatin, ezetimibe, or any other inactive ingredients present along with these medicines.

• Impaired Liver function

  This medicine is not recommended for use in patients with active liver diseases or any abnormality in the liver function tests due to the increased risk of severe adverse effects. It is also not recommended for use in patients with a moderate-to-severe liver function impairment due to the increased risk of worsening of the patient's condition.

• Pregnancy

  This medicine is not recommended for use in pregnant women due to the increased risk of fetal harm. Your doctor may prescribe a safer alternative based on your clinical condition.

• Breast-feeding

  This medicine is not recommended for use in breastfeeding women. Your doctor may prescribe a safer alternative based on your clinical condition.

• Cognitive impairment

  This medicine may cause forgetfulness, memory loss, confusion, etc. These side effects are reversible and usually disappear once the therapy is discontinued.

• Liver enzymes

  This medicine may increase the liver enzyme levels in some patients. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

• Myopathy and Rhabdomyolysis

  This medicine may cause muscle breakdown and rhabdomyolysis in some patients, a condition which can be fatal. This may cause symptoms such as severe tiredness and weakness. This risk is especially higher in the elderly population and in patients with active muscle disorders. Report any unusual symptoms to the doctor immediately. Replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

• Alcohol consumption

  This medicine may cause liver and kidney injuries in patients consuming alcohol very frequently and in large quantities. Hence, consumption of alcohol should be avoided during treatment with this medicine.

• Fusidic acid

  Coadministration of systemic fusidic acid and this combination medicine is not recommended due to the increased risk of rhabdomyolysis. Replacement with a suitable alternative should be considered based on the clinical condition of the patient.

• Coumarin Anticoagulants

  This medicine should be used with caution in patients receiving coumarin anticoagulants such as warfarin due to the increased risk of excessive bleeding. Close monitoring of International Normalized Ratio (INR) is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

• Pediatric use

  The safety and efficacy of this medicine have not been clinically established in children less than 10 years of age.

• Other medicines

  Many medicines interact with this combination medicine and their interaction may cause serious adverse effects. It is advised that you report to the doctor all your current medicines including any herbs and supplements before beginning treatment with this combination medicine.

Take this medicine as advised by your doctor. It can be taken with or without food. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.

• Can be taken with or without food, as advised by your doctor
• To be taken as instructed by doctor
• May cause sleepiness

• webmd.com - Ezetimibe-Simvastatin [Internet]. Available from: https://www.webmd.com/drugs/2/drug-91437/ezetimibe-simvastatin-oral/details [cited 6/7/2020].