Sonib Tablet 200mg (Sorafenib)

 25,421.00


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SKU: pu_177902 Category:

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    How it works

    Sonib Tablet 200mg (Sorafenib) works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps stop the spread of cancer cells.

    Side effects

    Major & minor side effects for Sonib Tablet 200mg (Sorafenib)

    • Abdominal and stomach pain
    • Bleeding gums
    • Clay colored stools
    • Coughing
    • and
    • Loss of appetite
    • Difficulty in breathing
    • Hair loss
    • Fatigue
    • Headache
    • Dizziness
    • Dark urine
    • Hand-foot skin reactions

    Uses of Sonib Tablet 200mg (Sorafenib)

    What is it prescribed for?

    • Hepatocellular carcinoma

      This medicine is used for the treatment of cancer that affects the liver cells which cannot be removed by surgical procedures.

    • Advanced Renal Cell Carcinoma (RCC)

      This medicine is used for the treatment of advanced renal cell carcinoma (RCC), cancer that affects the cells of the kidney.

    • Thyroid cancer

      This medicine is used for the treatment of cancer that affects the thyroid, which is progressive and resistant to radioactive iodine therapy.

    Concerns

    Frequently asked questions

    • Onset of action

      The peak effect of this medicine can be observed within 3 hours of administration of the dose.

    • Duration of Effect

      The amount of time for which this medicine remains active in the body is not clinically established.

    • Safe with Alchohol?

      Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

    • Is it habit forming?

      No habit-forming tendencies were reported.

    • Usage in pregnancy?

      This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

    • Usage while breast-feeding?

      This medicine is not recommended for use in breastfeeding women. All the risks and benefits should be discussed with the doctor before using this medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition

    When not to use?

    • Allergy

      This medicine is not recommended for use in patients with a known allergy to Sonib Tablet 200mg (Sorafenib) or any other inactive ingredients present along with it.

    • Squamous cell lung cancer

      This medicine is not recommended for use with carboplatin and paclitaxel in patients with squamous cell lung cancer due to the increased risk of worsening of the patient's condition.

    Warnings

    Warnings for special population
    • Pregnancy

      This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

    • Breast-feeding

      This medicine is not recommended for use in breastfeeding women. All the risks and benefits should be discussed with the doctor before using this medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition

    General Warnings
    • Dermatological toxicities

      Hand-foot skin reaction and rash represent the most common adverse drug reactions with this medicine which generally appear during the first six weeks of treatment. Management of dermatological toxicities may include topical therapies for symptomatic relief, temporary treatment discontinuation and/or dose modification, or in severe or persistent cases, permanent discontinuation of the treatment.

    • Hypertension

      This medicine should be used with caution due to the increased risk of hypertension. It is usually mild to moderate, occurred early in the course of treatment, which is usually managed with standard antihypertensive therapy. Blood pressure should be monitored regularly while receiving this medicine. In cases of severe or persistent hypertension, or hypertensive crisis despite institution of antihypertensive therapy, permanent discontinuation of Soranib Tablet should be considered.

    • Hypoglycemia

      This medicine should be used with caution due to the increased risk of low blood glucose levels. In the case of symptomatic hypoglycemia, Soranib Tablet should be temporarily interrupted. Blood glucose levels in diabetic patients should be monitored regularly in order to assess if anti-diabetic medicinal product's dosage needs to be adjusted. An alternative treatment option should be considered in some cases based on the clinical condition.

    • Bleeding

      Increased risk of bleeding may occur with this medicine. It is advised to discontinue this medicine in case of serious bleeding events. Thyroid cancer patients with tracheal, bronchial, and esophageal infiltration should be treated with local therapy prior to administering this medicine due to the potential bleeding risk.

    • Heart Diseases

      This medicine should be used with caution in patients with cardiac diseases due to the increased risk of decreased blood flow to the heart or heart attack. It is advised to discontinue the therapy (temporary or permanent) in patients who develop these conditions.

    • Driving or Operating machinery

      Use of this medicine may cause dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience dizziness during the treatment with this medicine.

    • Use in Children

      This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.

    Dosage

    • Missed Dose

      Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose, then the missed dose can be skipped. Do not double your dose to make up for the missed dose. Contact your doctor for further instructions if you miss more than one scheduled dose of this medicine.

    • Overdose

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    Interactions

    Interaction with Medicines
    • Escitalopram severe
    • Ziprasidone severe
    • Efavirenz severe
    • Mifepristone severe
    • Clozapine severe
    • Moxifloxacin severe
    Disease interactions
    • moderate

      This medicine should be used with caution in patients with a history of interstitial pneumonitis or pulmonary fibrosis or those patients presenting with acute onset of new or progressive unexplained pulmonary symptoms such as dyspnea, cough, and fever pending diagnostic evaluation due to the increased risk of the lung toxicity. Appropriate dose adjustments and frequent clinical monitoring are advised in such cases. Replacement with a suitable alternative may be required based on the clinical condition.

    General Instructions

    Take Soranib Tablet exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. Take this medicine at least 1 hour before or 2 hours after the meal. You may require frequent blood tests and liver function tests while taking this medicine. You may also require frequent followups with your doctor to check the progress of treatment. Do not stop the use of this medicine without consulting your doctor.

    Other details

    • To be taken on an empty stomach
    • To be taken as instructed by doctor
    • May cause sleepiness

    References

    Additional Information>

    One of the following licensed pharmacy from the nearest location will deliver Sonib Tablet 200mg (Sorafenib). The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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