Syntomax Injection 5 IU 50 Amp

 500.00

Manufactured by:
Active Pharmaceutical Ingredient:
Drug Strength: 5 IU
Drug Form : Injection
Pack Size : 50 Amp
Does this requires a prescription ?Yes

Syntomax Injection contains Oxytocin | belongs to Oxytocic

SKU: pg_22096_30648 Categories: ,

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    How it works

    Syntomax Injection 5 IU 50 Amp works by increasing the concentration of calcium inside muscle cells that control contraction of the uterus. Increased calcium increases contraction of the uterus.

    Side effects

    Major & minor side effects for Syntomax Injection 5 IU 50 Amp

    • Nausea and Vomiting
    • Headache
    • Irregular heartbeat
    • Low blood pressure
    • Convulsions
    • Shortness of breath rare
    • Abdominal cramps

    Uses of Syntomax Injection 5 IU 50 Amp

    What is it prescribed for?

    • Induction of labor

      This medicine is used for relaxing and softening the cervix and induce uterine contractions for the induction of labor.

    • Augmentation of labor

      This medicine is used for the augmentation of labor by inducing uterine contractions when poor uterine contractions are assessed or medically necessary.

    • Postpartum bleeding

      This medicine is used for the control of postpartum hemorrhage (bleeding).

    • Termination of pregnancy

      This medicine is used for the termination of pregnancy by inducing uterine contractions and expelling the fetus out.

    Concerns

    Frequently asked questions

    • Onset of action

      The effect of this medicine can be observed immediately after the administration of the dose.

    • Duration of Effect

      The effects of this medicine last up to 2 to 3 hours after an intramuscular administration and 1 hour after an intravenous administration.

    • Safe with Alchohol?

      Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

    • Is it habit forming?

      No habit-forming tendencies were reported.

    • Usage in pregnancy?

      Use of this medicine is not recommended for pregnant women other than for the indicated uses such as the induction of labor and termination of pregnancy. Otherwise, the risk of birth defects, abortion, and other abnormalities are very high.

    • Usage while breast-feeding?

      This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

    When not to use?

    • Allergy

      This medicine is not recommended for use in patients with a known allergy to Syntomax Injection 5 IU 50 Amp or any other inactive ingredients present in the formulation.

    • Hypertonic uterine patterns

      This medicine is not recommended for use in case of hypertonic uterine patterns (a complication of labor induction).

    • Fetal distress

      This medicine is not recommended for use in case of fetal distress where delivery is not about to happen.

    • Cord presentation or prolapse

      This medicine is not recommended for use in conditions where vaginal delivery is not appropriate such as cord presentation or prolapse, Vasa Previa, total placenta previa, etc.

    • Cephalopelvic disproportion

      This medicine is not recommended for use in case of cephalopelvic disproportion, a pregnancy complication where the pelvis is inadequate to allow the fetus to easily fit through the pelvic opening.

    • Cesarean section

      This medicine is not recommended for patients who have a history of cesarean section due to the increased risk of adverse effects.

    Warnings

    Warnings for special population
    • Pregnancy

      Use of this medicine is not recommended for pregnant women other than for the indicated uses such as the induction of labor and termination of pregnancy. Otherwise, the risk of birth defects, abortion, and other abnormalities are very high.

    • Breast-feeding

      This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

    General Warnings
    • For hospital use only

      This medicine should be administered only by trained obstetrical personnel in a hospital setting with appropriate obstetrical care facilities.

    • Uncontrolled hypertension

      This medicine should be used with caution in women suffering from uncontrolled hypertension due to the risk of worsening of the condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

    • Cerebrovascular dysfunction

      This medicine should be used with caution in women with cerebrovascular dysfunction due to the risk of worsening of the condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

    • Volume overload

      This medicine may cause volume overload and water intoxication upon administration. Appropriate corrective measures, dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

    • Uterine rupture

      This medicine has been associated with cases of uterine rupture when used for labor induction in some cases. Caution is advised while using this medicine if the patient is in the late thirties and beyond or the delivery is cesarean.

    Dosage

    • Missed Dose

      Since this medicine is administered by a qualified healthcare professional in the clinical or hospital setting, the likelihood of a missed dose is very low.

    • Overdose

      Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

    Interactions

    Interaction with Medicines
    • Phenylephrine moderate
    • Dinoprostone severe
    • Atracurium moderate
    • Dopamine moderate
    • Midodrine moderate

    General Instructions

    This medicine should be administered only by trained obstetrical personnel in a hospital setting with appropriate obstetrical care facilities. Detect whether the patient is allergic to this medicine before initiating the treatment.

    Other details

    • Usage does not depend on food timings
    • To be taken as instructed by doctor
    • Does not cause sleepiness

    References

    Additional Information>

    How to use Syntomax Injection 5 IU 50 Amp

    Incomplete or inevitable abortion: Give by IV infusion at a rate of 10-20 milliunits (20-40 drops)/min.
    Induction or stimulation of labour: IV infusion (drip method) is the only acceptable method of parenteral administration for the induction or stimulation of labour. Accurate control of the rate of infusion flow is essential. An infusion pump or other device and frequent monitoring of strength, frequency and duration of contractions, resting uterine tone and fetal heart rate are necessary for the safe administration of oxytocin for the induction or stimulation of labour.
    Postpartum uterine bleeding: Give by IV infusion or IM.
    Reconstitution: Add oxytocin 1 mL (10 units) to 1000 mL of 0.9% aqueous NaCl or RL. The solution contains 10 milliunits/mL (0.01 units/mL). Use a constant infusion pump to accurately control the rate of infusion.
    Incomplete or inevitable abortion: Add oxytocin 10 units with 500 mL of physiologic saline solution or 5% dextrose in physiologic saline solution.
    Postpartum uterine bleeding: Add 10-40 units (max, 40 units) to 1000 mL of a nonhydrating diluent.
    Stability: Store at controlled room temperature 15°C-30°C (59°F-86°F).

    what are the adverse effects of Syntomax Injection 5 IU 50 Amp?

    Very occasionally prolonged or too rapid infusion of Syntocinon has antidiuretic effects, which may cause transient water intoxication, with headaches and nausea.

    What happens if I miss a dose of Syntomax Injection 5 IU 50 Amp?

    Adults: Induction or enhancement of labour: IV drip infusion of a 5% dextrose solution containing 1 IU syntocinon per 100 mL. The initial infusion rate of 1-4 milliunits/min equal to 0.1-0.4 mL/min (2-8 drops/min) may be gradually increased until the desired response is achieved (max 20 milliunits/min equal to 2 mL/min) or 40 drops/min) provided the foetal heart rate and the frequency and duration of contractions are carefully monitored.
    Third stage of labour and puerperium (haemorrhage, subinvolution of the uterus): 5-10 IU IM or 5 IU slowly IV.
    Caesarean section: 5 IU intramurally after delivery of the foetus. See literature.
    Children: Not recommended.

    One of the following licensed pharmacy from the nearest location will deliver Syntomax Injection 5 IU 50 Amp. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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