Content Details
Dr. Waqar Younus
MBBS
Information on this page was last modified on : 2024/06/01 4:19:12 PM
tafinlar (dabrafenib) 75 mg 120 capsule
Belongs to CategoryMedicine & Health
How It Works
Tafinlar (generic name dabrafenib) is a kinase inhibitor that works by targeting and inhibiting the activity of mutated forms of the BRAF protein. BRAF mutations are commonly found in certain types of cancer, including melanoma and non-small cell lung cancer (NSCLC). By inhibiting the mutated BRAF protein, Tafinlar helps to slow down or stop the growth of cancer cells.
Side Effects
- Fever
- Fatigue
- Nausea
- Diarrhea
- Skin rash
Indications
- Tafinlar is indicated for the treatment of unresectable or metastatic melanoma with BRAF V600E mutation, as detected by an FDA-approved test.
- It is also used in combination with trametinib for the treatment of BRAF V600 mutation-positive advanced non-small cell lung cancer (NSCLC).
Contraindications
- Severe hypersensitivity reaction to dabrafenib
- Severe renal impairment
- Severe hepatic impairment
Price Comparison in Different Countries
| Country | Price (per unit) | References |
|---|---|---|
| United States | $10,000 | GoodRx |
| United Kingdom | £7,000 | NHS |
| Australia | AUD 12,000 | PBS Australia |
| Canada | CAD 14,000 | Canadian Cancer Society |
| Germany | €9,000 | Apotheken Umschau |
Top 5 Global Brands
- Pfizer
- Roche
- Novartis
- Merck & Co.
- Johnson & Johnson
Additional Information:
One of the following licensed pharmacy from the nearest location will deliver tafinlar (dabrafenib) 75 mg 120 capsule. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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