₨ 10,000.00
MBBS
TOPOTEL 4mg Injection Vial
- Does this requires a prescription ? Yes
- Generic Name: Topotecan (HCl):4mg
- Manufactured by : Atco Laboratories Ltd
- Drug Strength : 4mg
- Drug Form : Injection
- Pack Size : Vial
- Product SKU : dis_20583
Topotecan (HCl):4mg | Cytotoxic (anti-neoplastic) drugs
Manufactured / Marketed By : Atco Product Form : InjectionPack Size : Vial Ingredients : Topotecan (HCl):4mgGeneric Category : Cytotoxic (anti-neoplastic) drugs
How it works
TOPOTEL 4mg Injection Vial by stopping the growth of cancer cells by inhibiting DNA synthesis.
Side effects
Major & minor side effects for TOPOTEL 4mg Injection Vial
- Nausea or Vomiting
- Diarrhea
- Hair loss
- Unusual tiredness or weakness
- Stomach pain
- Painful or difficult urination
- Black or tarry stools
- Weight loss
Uses of TOPOTEL 4mg Injection Vial
What is it prescribed for?
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Ovarian Cancer
This medicine is used in the treatment of cancer of the ovaries in patients who have not adequately responded to other anticancer medications.
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Cervical cancer
This medicine is used in the treatment of cervical cancer, a cancer of the cervix characterized by symptoms such as bleeding in between periods, foul-smelling white discharge, low back pain, lower abdominal pain, etc.
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Small Cell Lung Cancer
This medicine is used in the treatment of small cell lung cancer, a highly malignant and aggressive cancer affecting the lungs.
Concerns
Frequently asked questions
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Onset of action
The amount of time required for this medicine to show its action is not clinically established.
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Duration of Effect
The amount of time for which this medicine remains active in the body is not clinically established.
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Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
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Is it habit forming?
No habit-forming tendencies were reported.
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Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking/receiving this medicine.
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Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking/receiving this medicine.
When not to use?
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Allergy
This medicine is not recommended for use in patients with a known allergy to TOPOTEL 4mg Injection Vial or any other inactive ingredients present along with this medicine.
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Severe myelosuppression
This medicine is not recommended for use in patients with a severe bone marrow suppression (neutrophils less than 1.5 x 109/l or platelet count less than 100 x 109/l) since it may worsen the patient's condition.
Warnings
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Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking/receiving this medicine.
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Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking/receiving this medicine.
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Diarrhea
The oral capsule form of this medicine may cause severe diarrhea in some patients. It is advised to withhold the therapy with this medicine in patients with severe diarrhea. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
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Liver impairment
This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of worsening of the patient's condition. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
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Kidney impairment
This medicine should be used with caution in patients with kidney diseases due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
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Risk of infections
Use of this medicine may weaken the immune system and may make you more vulnerable to infections. It is advised that you avoid coming in contact with people suffering from an infection while receiving this medicine.
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Bonemarrow suppression
This medicine should be used with caution in patients having conditions like thrombocytopenia, agranulocytosis, anemia, or bone marrow suppression due to the increased risk of worsening of the patient's condition. A complete blood count should be performed before initiating treatment with this medicine. Close monitoring of blood counts is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
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Use in children
This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.
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Driving or operating machinery
Use of this medicine may cause dizziness, visual disturbances, and tiredness. Hence, it is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery during treatment with this medicine.
Dosage
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Missed Dose
Injection: Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low. If you miss any scheduled session, contact your doctor immediately for further instructions. Capsule: Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
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Overdose
Injection: Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected. Capsule: Seek emergency medical treatment or contact the doctor in case of an overdose.
Interactions
Interaction with Medicines- Live attenuated vaccines and related products severe
- Adalimumab severe
- Clozapine severe
- Deferiprone severe
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severe
This medicine is not recommended for use in patients with active infections since it may worsen the patient's condition. Replacement with a suitable alternative should be considered under your doctor's supervision.
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severe
This medicine should be used with extreme caution in patients with known myelosuppression since it may worsen the patient's condition. Close monitoring of blood cell counts is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
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severe
This medicine should be used with caution in patients with kidney diseases due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
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moderate
This medicine should be used with caution in patients with a history of interstitial lung disease presenting with acute onset of new or progressive unexplained pulmonary symptoms such as dyspnea, cough, and fever pending diagnostic evaluation due to the increased risk of the lung toxicity. Close monitoring of lung function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
General Instructions
Injection: This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine. Capsule: Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Do not stop the use of this medicine without consulting your doctor.
Other details
- Can be taken with or without food, as advised by your doctor
- To be taken as instructed by doctor
- May cause sleepiness
References
- dailymed - TOPOTECAN [Internet]. Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=729b2b22-1344-44f3-b614-14f6ec3c263e [cited 1/30/2021]. 2020
One of the following licensed pharmacy from the nearest location will deliver TOPOTEL 4mg Injection Vial. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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