
MBBS
Ultomiris ravulizumab 300 mg Injection
- Generic Name: ravulizumab
- Drug Strength : 300mg
How it Works
Ultomiris, with the active ingredient ravulizumab, is a monoclonal antibody used in the treatment of paroxysmal nocturnal hemoglobinuria (PNH) in adults. Ravulizumab targets complement component C5 and inhibits its cleavage into C5a and C5b. By inhibiting C5 cleavage, ravulizumab prevents the generation of the terminal complement complex C5b-9, which is responsible for cell lysis in PNH. This action reduces hemolysis and the associated symptoms of PNH.
Side Effects
- Headache
- Fatigue
- Upper respiratory tract infections
- Nausea
- Viral infections
- Diarrhea
- Abdominal pain
- Back pain
- Injection site reactions (pain, erythema, bruising)
- Hypertension (high blood pressure)
- Dizziness
- Insomnia
Indications
- Paroxysmal nocturnal hemoglobinuria (PNH) in adults
Contraindications
- Hypersensitivity to ravulizumab or any of its excipients
- Meningococcal infection or a history of meningococcal infection
- Patients not currently vaccinated against meningococcal infection
Price Comparison in Different Countries
Country | Price (USD) | Website |
---|---|---|
United States | $19,000 per injection | GoodRx |
Canada | $18,000 per injection | PharmacyChecker |
United Kingdom | £16,000 per injection | NHS |
Australia | AUD 28,000 per injection | PBS |
Germany | €20,000 per injection | Aponeo |
Top 5 Global Brands
- Ultomiris (Alexion Pharmaceuticals)
- Soliris (Alexion Pharmaceuticals)
- Ravulizumab (Alexion Pharmaceuticals)
- Elzonris (Takeda Pharmaceuticals)
- Cablivi (Ablynx, a Sanofi Company)
One of the following licensed pharmacy from the nearest location will deliver Ultomiris ravulizumab 300 mg Injection. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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