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Unerif tablet 450 mg 100's

Belongs to Category

Unerif tablet contains Rifampicin | belongs to Rifamycin

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How it works

Unerif tablet 450 mg 100’s works by interfering with the bacterial DNA synthesis and stops the growth of the bacteria.

Side effects

Major & minor side effects for Unerif tablet 450 mg 100’s

  • Abdominal pain severe
  • Dizziness severe
  • Headache severe
  • Yellow colored eyes or skin severe
  • Nausea and Vomiting severe
  • Skin rash severe
  • Loss of appetite severe
  • Unusual behavior
  • Muscle pain
  • Weakness

Uses of Unerif tablet 450 mg 100’s

What is it prescribed for?

  • Tuberculosis

    Unerif tablet 450 mg 100’s is used in the treatment of tuberculosis which is a lung infection caused by Mycobacterium tuberculosis.

  • Meningococcal Meningitis

    Unerif tablet 450 mg 100’s is used in the treatment of meningococcal meningitis which is an infection that affects the brain and spinal cord caused by Neisseria meningitidis.

Concerns

Frequently asked questions

  • Onset of action

    The peak effect of this medicine can be observed in 2 to 4 hours.

  • Duration of Effect

    The effect of this medicine lasts for an average duration of 9 to 12 hours.

  • Safe with Alchohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    No habit forming tendencies were reported.

  • Usage in pregnancy?

    This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

  • Usage while breast-feeding?

    This medicine is excreted in breast milk. It is recommended for breastfeeding women only if clearly needed. The risk and benefits should be discussed with the doctor before taking this medicine.

When not to use?

  • Allergy

    Not recommended in patients with known allergy to [post_titlte].

  • Antiviral medications

    Not recommended in patients receiving antiviral therapy due to the decrease in the effect of antiviral medications.

Warnings

Warnings for special population
  • Pregnancy

    This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

  • Breast-feeding

    This medicine is excreted in breast milk. It is recommended for breastfeeding women only if clearly needed. The risk and benefits should be discussed with the doctor before taking this medicine.

Warnings

Warnings for special population
  • Liver injury

    This medicine may cause liver injury, therefore should be used with caution. The liver function tests should be performed before starting the treatment. The dose should be adjusted based on the severity of liver disease.

  • Diabetes

    This medicine may alter the blood glucose levels. Inform the doctor about your medical condition before starting the treatment. Monitoring of blood glucose levels is necessary.

  • Drug-resistance

    Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that is drug resistant.

Dosage

  • Missed Dose

    If you miss a dose of Unerif tablet 450 mg 100’s , take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

  • Overdose

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

Interaction with Medicines
  • Clopidogrel moderate
  • Propranolol moderate
  • Warfarin severe
  • Atorvastatin severe
Disease interactions
  • severe

    Inform the doctor if you have liver disease before receiving this medicine. Close monitoring of liver function is necessary. Any signs of an increase in the liver enzymes should be informed to the doctor. The treatment should be stopped temporarily until the liver enzymes return to normal.

Lab interactions

General Instructions

Take Unerif tablet 450 mg 100’s as advised by your doctor. Do not take in larger amounts than advised. It is advised to take this medicine at the same time every day. Do not stop taking the medicine without consulting your doctor. Ensure that the course of treatment is completed to prevent the spread of infection. Consult the doctor if you experience any undesirable effects

Other details

  • To be taken before food
  • To be taken as instructed by doctor
  • Does not cause sleepiness

References

what are the adverse effects of Unerif tablet 450 mg 100’s

Heartburn, epigastric distress, anorexia, nausea, vomiting, diarrhoea, sore mouth. Rash, pruritus, urticaria. Eosinophilia, thrombocytopenia. Muscular weakness, pain in extremities. Visual disturbances, Haemoglobinuria, hematuria. Menstrual disturbances. Other blood dyscrasias, headache, dizziness, GI upset, purpura, pyrexia, chills, raised LFTs, secretions and soft contact lenses, skin reactions.

What is the dose of Unerif tablet 450 mg 100’s

Tuberculosis: Adults: 450-600 mg daily in a single dose 30 min before breakfast. Children: Up to 20 mg/kg daily; max 600 mg as a single dose.
Multibacillary leprosy: Adults: 600 mg once-monthly, supervised. lt;35 kg: 450 mg. Multibacillary leprosy should be treated for at least 2 yrs.
Paucibacillary leprosy: Adults: 600 mg once-monthly, supervised. lt;35 kg: 450 mg. Paucibacillary leprosy should be treated for 6 months.
Brucellosis, legionnaire’s disease, endocarditis and serious staphylococcal infections: Adults: In combination with other drugs, by oral or IV inf, 0.6-1.2 gm daily (in 2-4 divided doses).

One of the following licensed pharmacy from the nearest location will deliver Unerif tablet 450 mg 100’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts the your request based on valid prescription and availability.

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