Unexolone tablet 10 mg 500's

How it works

It works by increasing the movement of food in the stomach and the intestine.

Side effects

Major & minor side effects for Unexolone tablet 10 mg 500’s

• Dizziness severea
• Abdominal pain severea
• Convulsions severea
• Headache severea
• Skin rash severea
• Irregular heartbeat severea
• Diarrhea
• Restlessness
• Breast pain and tenderness
• Increased flow of breast milk

Uses of Unexolone tablet 10 mg 500’s

What is it prescribed for?

• Chemotherapy induced nausea and vomiting

  Unexolone tablet 10 mg 500’s is used to treat nausea and vomiting associated with the use of chemotherapy medicines for the treatment of cancer.

• Gastroparesis

  Unexolone tablet 10 mg 500’s is used in the treatment of Gastroparesis since it increases the gastric emptying and prevents nausea and vomiting.

• Gastroesophageal Reflux Disease

  Unexolone tablet 10 mg 500’s is used in the treatment of Gastroesophageal Reflux Disease since it increases the gastric emptying and reduces the reflux of gastric contents.

When not to use?

• Allergy

  This medicine is not recommended for use in patients with a known allergy to Unexolone tablet 10 mg 500’s .

• Gastrointestinal disorders

  This medicine is not recommended for use in patients with gastrointestinal disorders like gastrointestinal hemorrhage, mechanical obstruction, and gastrointestinal perforation.

• Seizure disorder

  This medicine is not recommended for use in patients with a known history of seizures.

• Pheochromocytoma

  This medicine is not recommended for use in patients with conditions like pheochromocytoma due to an increase in the risk of hypertensive crisis (very severe increase in the blood pressure).

Warnings

• Pregnancy

  This medicine is recommended for use in pregnant women only if necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

• Breast-feeding

  This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Warnings

• Neuroleptic Malignant Syndrome (NMS)

  Unexolone tablet 10 mg 500’s is known to cause Neuroleptic Malignant Syndrome which is characterized by hyperthermia (fever), muscle rigidity, and altered consciousness. Report to the doctor immediately if these symptoms appear. Discontinue Unexolone tablet 10 mg 500’s treatment if the symptoms persist.

• Depression

  Unexolone tablet 10 mg 500’s may cause depression in patients with or without the prior history of depression. Any symptoms of change in behavior or suicidal thoughts should be informed to the doctor on priority. Discontinue the treatment if the symptoms worsen.

Interactions

• Phenytoin moderate
• Phenytoin moderate
• Chlorpromazine severe

• severe

  Unexolone tablet 10 mg 500’s is not recommended for use in patients with gastrointestinal disorders like mechanical bowel obstruction, bowel perforation, or gastrointestinal hemorrhage. An alternative treatment option should be considered based on the clinical condition.

• moderate

  Unexolone tablet 10 mg 500’s should be used with caution in patients with Parkinson's disease due to an increase in the risk of parkinsonian-like symptoms such as akinesia, bradykinesia, tremors, pill-rolling motion, and postural abnormalities. These symptoms will usually appear within the first 6 months of the treatment and subside within 2 to 3 months after discontinuation of the treatment.

General Instructions

Take Unexolone tablet 10 mg 500’s as advised by the doctor. Do not take this medicine if you have gastrointestinal disorders like mechanical bowel obstruction, bowel perforation, or gastrointestinal hemorrhage. Monitoring of blood pressure and symptoms like involuntary movements of the tongue, lips, face, and trunk is necessary while consuming this medicine.

Other details

• To be taken before food
• To be taken as instructed by doctor
• May cause sleepiness

References

• precto.com - Metoclopramide [Internet]. Available from: https://www.practo.com/medicine-info/metoclopramide-180-api [cited 18 september 2019]. 5 Jan 2018
• medlineplus.gov/ - Metoclopramide [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a684035.html [cited 18 september 2019]. 11 September 2019
• dailymed.nlm.nih.gov - Metoclopramide [Internet]. Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=50a3cf38-66dc-4fa5-8a45-adf959c987ab [cited 18 september 2019]. December 14, 2018