₨ 885.00
MBBS
Unistin Injection 50 mg 1 Vial
- Does this requires a prescription ? Yes
- Generic Name: Cisplatin
- Manufactured by : Al-Habib Pharmaceuticals
- Drug Strength : 50 mg
- Drug Form : Injection
- Pack Size : 1 vial
- Product SKU : pg_23474_32471
Unistin Injection contains Cisplatin | belongs to Alkylating agent
Alternate brands of Unistin Injection 50 mg 1 Vial
| Brand Name | Price | Savings |
|---|---|---|
| Unistin Injection 10 mg 10 Vial | ₨ 2,160.00 | You will pay -1275 more |
| Platosin Injection 50 mg 1 Vial | ₨ 675.00 | You can save 210 |
| Platosin Injection 10 mg 1 Vial | ₨ 200.00 | You can save 685 |
| Oncoplatin Injection 50 mg 1 Vial | ₨ 960.00 | You will pay -75 more |
| Kemoplat Injection 10 mg 1 Vial | ₨ 170.00 | You can save 715 |
How it works
Unistin Injection 50 mg 1 Vial works by stopping the growth of cancer cells by inhibiting the DNA synthesis.
Side effects
Major & minor side effects for Unistin Injection 50 mg 1 Vial
- Pain at the injection site severe
- Lower back pain severe
- Fever or chills severe
- Joint pain
- Ringing or buzzing in the ears
- Swelling of feet and lower legs
- Loss of taste
- Convulsions (seizures)
- Sour mouth
Uses of Unistin Injection 50 mg 1 Vial
What is it prescribed for?
-
Testicular Cancer
Cisplatin is used in the treatment of cancer of testicles, which produce the male sex hormones and sperm.
-
Ovarian Cancer
Cisplatin is used in the treatment of cancer that affects the ovaries.
-
Bladder cancer
Cisplatin is used in the treatment of bladder cancer, which is an organ that stores urine.
When not to use?
-
Allergy
Not recommended in patients with known allergy to Cisplatin or other platinum-containing compounds.
-
Impaired kidney function
Not recommended in patients with existing kidney impairment.
-
Impaired kidney function
This medicine may cause severe kidney injury. The risk may increase if taken with aminoglycoside antibiotics. Close monitoring of serum creatinine, urea, and sodium levels is necessary. Do not administer this medicine more than once every 3 to 4 weeks.
-
Hearing impairment
This medicine may cause the hearing problem which is more common in children. Audiometric testing should be performed before initiating the treatment and also before every dose. Any symptoms of the hearing problem should be reported to the doctor.
-
Allergy
This medicine may cause serious skin reactions. Discontinue the treatment if any symptoms of allergy appear and do not restart.
-
Blood cell count
This medicine may lower the white blood cells and platelets. Close monitoring of blood cell count is necessary. Do not start the treatment if the cell count is low.
-
Infections
The chances of occurring infections are more in patients receiving this medicine. Hold the chemotherapy and start with the broad-spectrum antibiotics if there are any signs and symptoms of fever. Close monitoring of the body temperature and the blood cell count is necessary.
Dosage
-
Missed Dose
It is advised not to miss any dose. If you missed any dose, you should contact your doctor immediately.
-
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
General Instructions
This medicine is given in multiple cycles. It is important to receive the every scheduled dose and make a note of next scheduled dose. Close monitoring of blood cells counts and kidney function.
Other details
- Usage does not depend on food timings
- To be taken as instructed by doctor
- May cause sleepiness
References
- practo.com - Cisplatin [Internet]. Available from: https://www.practo.com/medicine-info/cisplatin-63-api [cited 2 october 2019]. 16 Nov 2017
- medlineplus.gov - Cisplatin Injection [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a684036.html [cited 2 october 2019]. 11 September 2019
- dailymed.nlm.nih.gov - CISPLATIN [Internet]. Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b2b029f5-0d7e-4e7f-accc-b722aec34c68#ID36 [cited 2 october 2019]. August 6, 2019
How to use Unistin Injection 50 mg 1 Vial
IV: Pretreatment hydration with 1-2 Litre of fluid is recommended prior to cisplatin administration, adequate hydration and urinary output (gt;100 mL/hour). Should be maintained for 24 hours after administration. Aluminium containing IV infusion sets and needles should not be used due to binding with platinum. Rate of administration has varied from a 15 to 120 mins infusion, 1 mg/min infusion, 6-8 hour infusion, 24 hour infusion or per protocol. Maximum rate of infusion: 1 mg/min in patients with CHF. When administered as sequential infusions, taxane derivatives (docetaxel, paclitaxel) should be administered before platinum derivatives to limit myelosuppression and to enhance efficacy.
Standard IV dilution: Dose 250-1000 mL NS, D5/NS or D5/0.45% NaCl; stable for 72 hours at 4°C to 25°C (in combination with mannitol).
Compatibility: Stable in D5¼NS, D5½NS, D5NS, ¼NS, 1/3NS, ½NS, NS; incompatible with sodium bicarbonate 5%.
what are the adverse effects of Unistin Injection 50 mg 1 Vial?
Nausea, vomiting, diarrhoea, renal impairment, leucopenia, thrombocytopenia, anaemia, aneilema, tinnitus, hearing loss, anaphylactic reactions (e.g. drug eruption); elevated GOT, GPT, ALP; malaise, dizziness, calvities, flush, oedema.
What happens if I miss a dose of Unistin Injection 50 mg 1 Vial?
Metastatic testicular tumours: Adults: 20 mg/m² daily for 5 consecutive days (days 1 to 5) every 3rd wk for 4 courses. 30 units of bleomycin on the 2nd day of each wk for 12 consecutive doses. 0.2 mg/kg body weight of vinblastine on days 1 and 2 of every 3rd wk four courses.
Metastatic ovarian tumours: Once every 3 wk 50 mg/m² and 500 mg/m² of cyclophosphamide. As a single agent: 100 mg/m² by intravenous route every 4th wk.
One of the following licensed pharmacy from the nearest location will deliver Unistin Injection 50 mg 1 Vial. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
Questions and Answers
There are no questions yet. Be the first to ask a question about this product.
Reviews
There are no reviews yet.