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Varedet Injection 500 mg 1 Vial

Varedet Injection contains Vancomycin | belongs to Glycopeptide

Alternate brands of Varedet Injection 500 mg 1 Vial

Brand Name Price Savings
Vinvin Injection Lyophilised IV Infusion (Dry) 500 mg 1 Vial  700.00 You can save 111.5
Vinvin Injection Lyophilised IV Infusion (Dry) 1 gm 1 Vial  1,130.00 You will pay -318.5 more
Vinjec Injection 1 gm 1 Vial  1,207.00 You will pay -395.5 more
Vinjec Injection 500 mg 1 Vial  744.00 You can save 67.5
Varedet Injection 1 gm 1 Vial  1,399.76 You will pay -588.26 more
List of alternate brands

How it works

Varedet Injection 500 mg 1 Vial works by inhibiting the growth of the bacteria by interfering with the bacterial cell wall synthesis

Side effects

Major & minor side effects for Varedet Injection 500 mg 1 Vial

  • Swelling of face, lips, eyelids, tongue, hands and feet severe
  • Fever severe
  • Back pain severe
  • Drowsiness severe
  • Changes in urine frequency severe
  • Skin rash severe
  • Abdominal pain
  • Headache
  • Bitter taste
  • Excessive air or gas in stomach

Uses of Varedet Injection 500 mg 1 Vial

What is it prescribed for?

  • Bacterial Septicemia

    Varedet Injection 500 mg 1 Vial is used in the treatment of septicemia which is an infection of the blood caused by Staphylococci and Streptococcus pyogenes.

  • Endocarditis

    Varedet Injection 500 mg 1 Vial is used in the treatment of endocarditis which is an infection of the inner lining of the heart caused by Streptococcus species and Staphylococcus species

  • Osteomyelitis

    Varedet Injection 500 mg 1 Vial is used in the treatment of bone infections like osteomyelitis caused by Staphylococci and Streptococci species.

  • Skin and Soft tissue infections

    Varedet Injection 500 mg 1 Vial is used to treat skin and soft tissue infections caused by Staphylococcus aureus and Streptococcus pyogenes.

  • Surgical prophylaxis

    Varedet Injection 500 mg 1 Vial is used to treat infections during surgery caused by Staphylococci and Streptococci species.

Concerns

Frequently asked questions

  • Onset of action

    The peak effect of this medicine can be observed immediately after intravenous infusion,

  • Duration of Effect

    The effect of this medicine lasts for an average duration of 12 to 24 hours.

  • Safe with Alchohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    No habit forming tendency have been reported.

  • Usage in pregnancy?

    This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

  • Usage while breast-feeding?

    This medicine is not recommended for use during breastfeeding unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

When not to use?

  • Allergy

    Not recommended in the patients allergic to Varedet Injection 500 mg 1 Vial .

Warnings

Warnings for special population
  • Pregnancy

    This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

  • Breast-feeding

    This medicine is not recommended for use during breastfeeding unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

General Warnings
  • Hearing problem

    Excessive intravenous doses of this medicine may alter the hearing ability. Any symptoms of the hearing problem should be reported to the doctor.

  • Impaired kidney function

    This medicine may increase the risk of kidney injury, especially in the elderly population. The dose of this medicine should be adjusted based on the CrCl. Any signs and symptoms of kidney injury like fluid accumulation, weight gain should be reported to the doctor.

  • Drug-resistance

    Usage of Varedet Injection 500 mg 1 Vial without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that is drug resistant.

Dosage

  • Missed Dose

    The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

  • Overdose

    Seek emergency medical treatment or contact the doctor in case of overdose.

Interactions

Interaction with Medicines
  • Metformin moderate
  • Ethinyl Estradiol moderate
  • Cholera Vaccine severe
  • Ketorolac moderate

General Instructions

Take Varedet Injection 500 mg 1 Vial as instructed by your doctor. Do not take in larger or smaller amounts than advised. Drink adequate amount of water to prevent the irritation in the intestine. Do not stop taking this medicine without consulting the doctor.

Other details

  • Can be taken with or without food, as advised by your doctor
  • To be taken as instructed by doctor
  • May cause sleepiness

References

Additional Information:

How to use Varedet Injection 500 mg 1 Vial

IV: Administer vancomycin by IV intermittent infusion over at least 60 min at a final conc not to exceed 5 mg/ mL. Administration of antihistamines just before the infusion may also prevent or minimize Red man syndrome.
Compatibility: Stable in dextran 6% in NS, D5W, D5% NS, RL, D5% RL, NS, D10W.
Y-site administration:
Drug to Drug IV Compatibility: Acyclovir, amikacin, amiodarone, bumetanide, calcium gluconate, cimetidine, cisatracurium, diltiazem, diphenhydramine, dobutamine, dopamine, enalapril, epinephrine, esmolol, famotidine, fentanyl, fluconazole, gentamicin, hydromorphone, imipenem, insulin regular, labetalol, levofloxacin, linezolid, lorazepam, magnesium sulphate, meropenem, methylprednisolone, metoclopramide, midazolam, milrinone, morphine, nitroglycerin, nitroprusside, norepinephrine, ondansetron, phenylephrine, ranitidine, tobramycin, vasopressin, vecuronium.
Drug to Drug IV Incompatibility: Albumin, amphotericin B cholesteryl sulphate complex, cefepime, furosemide, gatifloxacin, heparin, idarubicin, lansoprazole, omeprazole, piperacillin/tazobactam.
In syringe: Incompatible with heparin.
When admixed: Incompatible with amobarbital, chloramphenicol, chlorothiazide, dexamethasone sodium phosphate, penicillin G potassium, pentobarbital, phenobarbital, phenytoin.
Stability: Store vials at 20°C-25°C (68°F-77°F). After initial reconstitution with SWFI, D5W or NS, solutions are stable for 14 days if refrigerated. After further dilution with D5W or NS, the solution may be stored in a refrigerator for 14 days without significant loss of potency. Solutions diluted with D5NS, RL, D5RL may be stored in a refrigerator for 96 hours. Store pharmacy bulk packages at 20°C-25°C (68°F-77°F). Discard pharmacy bulk packages no later than 4 hours after initial closure puncture.

what are the adverse effects of Varedet Injection 500 mg 1 Vial?

Infusion related events (anaphylactoid reactions, flushing), nephrotoxicity, ototoxicity, neutropenia, nausea, chills, fever, rashes, eosinophilia, phlebitis, decreased BP, dyspnoea, stridor, pruritus, mucosal inflammation, eosinophilia, phlebitis, severe pain at inj site, Stevens-Johnson syndrome, toxic epidermal necrolysis, bullous dermatosis (discontinue).

What happens if I miss a dose of Varedet Injection 500 mg 1 Vial?

IV: Adults: 500 mg every 6 hr or 1 gm every 12 hr. Children: 10 mg/kg every 6 hr. Infants & Neonates: 15 mg/kg 1 dose then 10 mg/kg every 12 hr for 1st wk of life, & every 8 hr up to 1 mth of age.

One of the following licensed pharmacy from the nearest location will deliver Varedet Injection 500 mg 1 Vial. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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