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Information on this page was last modified on : 2024/06/01 6:21:23 PM

VENCLYXTO 100 MG 112 TABLET

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How it Works

VENCLYXTO contains the active ingredient venetoclax, which is a selective inhibitor of the B-cell lymphoma-2 (BCL-2) protein. BCL-2 prevents apoptosis (programmed cell death) in cancer cells, allowing them to survive and proliferate. Venetoclax works by binding to BCL-2, blocking its function and promoting apoptosis in cancer cells, particularly in chronic lymphocytic leukemia (CLL) cells that overexpress BCL-2.

Side Effects

  • Neutropenia (low levels of neutrophils)
  • Anemia
  • Thrombocytopenia (low platelet count)
  • Nausea
  • Diarrhea
  • Upper respiratory tract infection
  • Fatigue
  • Fever
  • Musculoskeletal pain
  • Swelling of limbs (edema)

Indications

  • Treatment of adult patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).
  • Treatment of adult patients with acute myeloid leukemia (AML) in combination with azacitidine, decitabine, or low-dose cytarabine in patients who are newly diagnosed and are 75 years or older, or who have comorbidities precluding the use of intensive induction chemotherapy.

Contraindications

  • Hypersensitivity to venetoclax or any of its excipients
  • Use with strong CYP3A inhibitors at initiation and during dose ramp-up
  • Patients with severe hepatic impairment
  • History of tumor lysis syndrome (TLS)
  • Concomitant use with drugs known to increase the risk of tumor lysis syndrome

Price Comparison in Different Countries:

Country Price (USD) Website
United States $9,000 Drugs.com
Canada $10,500 Drugs.com
United Kingdom £7,500 NHS UK
Australia $12,000 AUD Chemist Warehouse Australia
Germany €8,500 Apotheke

Top 5 Global Brands:

AbbVie
Genentech
Janssen Pharmaceuticals
AstraZeneca
Roche
VENCLYXTO, developed by AbbVie and marketed by various pharmaceutical companies globally, stands as a significant advancement in the treatment of CLL and SLL, providing improved outcomes and hope for patients with these hematologic malignancies.

Additional Information:

One of the following licensed pharmacy from the nearest location will deliver VENCLYXTO 100 MG 112 TABLET. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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