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Information on this page was last modified on : 2020/06/26 4:18:35 PM

Venomether Injection 80 mg 6 Ampx1 mL

Belongs to Category

Venomether Injection contains Artemether | belongs to Artemisinin derivative

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How it works

This medicine works by interfering with certain vital functions in the cell of the malarial parasite present in the blood.

Side effects

Major & minor side effects for Venomether Injection 80 mg 6 Ampx1 mL

  • Nausea and Vomiting
  • Stomach discomfort and pain
  • Dizziness
  • Stomach irritation
  • Ringing or buzzing in the ears
  • Reduction in blood cell count severe
  • Increased heartbeat severe
  • Elevated liver enzymes severe

Uses of Venomether Injection 80 mg 6 Ampx1 mL

What is it prescribed for?

  • Acute uncomplicated malaria

    This medicine is used to treat malaria caused by Plasmodium falciparum strain of the parasite. It may also be used for the treatment of malaria that are resistant to other medicines.

Concerns

Frequently asked questions

  • Onset of action

    The effect of this medicine can be observed within 6-8 hours of administration.

  • Duration of Effect

    The effect of this medicine lasts for an average duration of 2-3 days.

  • Safe with Alchohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    No habit forming tendencies were reported.

  • Usage in pregnancy?

    Use of this medicine in pregnant women is not recommended unless absolutely necessary. The effect of this medicine on pregnancy is not clearly established and hence should be used only in life-threatening situations.

  • Usage while breast-feeding?

    Use of this medicine while breastfeeding is not recommended unless necessary. Your doctor will determine whether or not to use this medicine.

When not to use?

  • Allergy

    This medicine is not recommended for use if you have a known history of allergy to Venomether Injection 80 mg 6 Ampx1 mL or any other Artemisinin derivatives.

Warnings

Warnings for special population
  • Pregnancy

    Use of this medicine in pregnant women is not recommended unless absolutely necessary. The effect of this medicine on pregnancy is not clearly established and hence should be used only in life-threatening situations.

  • Breast-feeding

    Use of this medicine while breastfeeding is not recommended unless necessary. Your doctor will determine whether or not to use this medicine.

Warnings

Warnings for special population
  • Severe malaria

    This medicine should be used to treat malaria only when it is severe and other medicines like quinine are proving to be ineffective.

  • Liver/kidney impairment

    This medicine should be used with caution in patients having an impaired liver/kidney function. If the impairment is very severe, then the use of this medicine should be avoided.

  • Heart disease

    This medicine should be used with caution in patients suffering from a pre-existing condition of the heart. Appropriate dose adjustments and frequent clinical monitoring are recommended in such cases.

  • Drug resistance

    It is strongly recommended to take this medicine for the entire prescribed duration even when symptoms resolve or improve. Failure to do so might result in parasitic resistance to the drug and treatment of further infection with this medicine would become difficult.

Dosage

  • Missed Dose

    Contact your doctor immediately if you miss a scheduled dose of this medicine.

  • Overdose

    Contact your doctor immediately if an overdose with this medicine is suspected.

Interactions

Interaction with Medicines
  • Erythromycin severe
  • Quinidine moderate
  • Chlorpromazine moderate
  • Quetiapine severe
  • Terfenadine moderate
Disease interactions
  • moderate

    This medicine should be administered with caution in patients having an impaired liver function. Appropriate diagnostic tests must be performed before determining the dose regimen. Suitable dose adjustment and frequent monitoring may be needed to ensure safe and effective use.

  • moderate

    This medicine should be administered with caution in patients having an impaired kidney function. Appropriate diagnostic tests must be performed before determining the dose regimen. Suitable dose adjustment and frequent monitoring may be needed to ensure safe and effective use.

Lab interactions

General Instructions

Take Venomether Injection 80 mg 6 Ampx1 mL as prescribed by the doctor. Do not take more or less than the recommended quantity and duration. It is advised to take this medicine under the supervision of a doctor or a healthcare professional.

Other details

  • To be taken with food
  • To be taken as instructed by doctor
  • Effect on sleep is not established

References

How to use Venomether Injection 80 mg 6 Ampx1 mL

Deep IM injection or slow IV infusion. IM injection: Dissolve 60 mg of Artesunate with 1 mL of 5% sodium bicarbonate solution for injection before use. IV infusion: Dissolve 60 mg of Artesunate with 1 mL of 5% sodium bicarbonate solution for injection and add 5 mL of 0.9% sodium chloride solution for injection before use to make 1 mL containing 10 mg of Artesunate. Injection must follow immediately soon after dissolution, if the solution appears cloudy or sediment occurs, it should be rejected.

what are the adverse effects of Venomether Injection 80 mg 6 Ampx1 mL

Transient and reversible reticulocytopenia, drug fever, drug rash, bradycardia, transient first degree heart block and transient & reversible elevation of serum transaminases. Nausea, abdominal pain, diarrhoea, headache.

What is the dose of Venomether Injection 80 mg 6 Ampx1 mL

Adults: IM or IV infusion: First dose 120 mg; followed by 60 mg after 4-6 hr; then 60 mg after every 24 hr once daily. The total duration of treatment is 5 consecutive days. Total doses are 360-480 mg for adults. Children: IM or IV infusion: Age 7 yr or more, same as adult dose. Below 7 yr age: 1.5 mg/kg. Both the age group children should be given the sec dose after 4-6 hr; then one dose after every 24 hr once daily. The total duration of treatment is 5 consecutive days.

One of the following licensed pharmacy from the nearest location will deliver Venomether Injection 80 mg 6 Ampx1 mL. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts the your request based on valid prescription and availability.

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