₨ 400.00
MBBS
Vinblas Injection 10 mg 1 Vial
- Does this requires a prescription ? Yes
- Generic Name: Vinblastine
- Manufactured by : Pharmedic Laboratories
- Drug Strength : 10 mg
- Drug Form : Injection
- Pack Size : 1 vial
- Product SKU : pg_24031_33303
Vinblas Injection contains Vinblastine | belongs to Vinca alkaloid
Alternate brands of Vinblas Injection 10 mg 1 Vial
| Brand Name | Price | Savings |
|---|---|---|
| Velbastine Injection 10 mg 1 Vial | ₨ 595.00 | You will pay -195 more |
| Cytoblastin Injection 10 mg 1 Vial | ₨ 650.00 | You will pay -250 more |
How it works
Vinblas Injection 10 mg 1 Vial works by slowing or stopping the growth of cancer cells.
Side effects
Major & minor side effects for Vinblas Injection 10 mg 1 Vial
- Blood in urine and stools
- Injection site pain and warmth
- Fever and chills
- Unusual bleeding or bruising
- Joint pain
- Swelling of feet or lower legs
- Dizziness rare
Uses of Vinblas Injection 10 mg 1 Vial
What is it prescribed for?
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Breast cancer
This medicine is used in the treatment of cancer that develops in the breast cells.
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Kaposi's Sarcoma
The medicine is used in the treatment of Kaposi's Sarcoma, a type of cancer that affects the cells that line the blood and lymph vessels.
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Testicular Cancer
The medicine is used for the treatment of testicular cancer, which affects the male sex organ (testicles).
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Mycosis Fungoides
This medicine is used in the treatment of Mycosis fungoides, the most common type of blood cancer (cutaneous t-cell lymphoma) which is characterized by rash, skin lesions, itchy skin, etc.
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Choriocarcinoma
This medicine is used in the treatment of choriocarcinoma, a type of cancer that affects the uterus.
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Lymphoma
This medicine is used in the treatment of lymphoma, a type of cancer that affects the lymphocytes (infection-fighting cells of the immune system).
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Histiocytosis X.
This medicine is used in the treatment of histiocytosis X, characterized by an abnormal increase in the number of specialized white blood cells called histiocytes (L-group).
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Hodgkin's Disease
The medicine is used for the treatment of Hodgkin's Disease, which is one of a group of cancers that develop in the lymphatic system (lymphoma).
Concerns
Frequently asked questions
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Onset of action
The amount of time required for this medicine to show its action is not clinically established.
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Duration of Effect
The amount of time for which this medicine remains active in the body is not clinically established.
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Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
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Is it habit forming?
No habit-forming tendencies were reported.
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Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
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Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
When not to use?
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Allergy
This medicine is not recommended for use in patients with a known allergy to Vinblas Injection 10 mg 1 Vial or any other inactive ingredients present in the formulation.
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Active untreated infection
This medicine is not recommended for use in patients with an active bacterial infection due to the increased risk of worsening of the patient's condition.
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Myelosuppression
This medicine is not recommended for use in patients who are suffering from myelosuppression due to the increased risk of worsening of the patient's condition.
Warnings
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Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
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Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
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Intravenous adminstration
This medicine should only be administered into a vein but in some cases, the medicine may leak into surrounding tissue leading to severe irritation or damage. The physician or nurse will monitor the site of administration for this reaction. Report to the doctor immediately if you experience any of the following symptoms: pain, itching, redness, swelling, blisters, or sores in the place where the medication was injected.
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Liver Disease
This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of adverse effects. Close monitoring of the liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
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Driving or Operating machinery
Use of this medicine may rarely cause drowsiness or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during the treatment with this medicine.
Dosage
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Missed Dose
Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low. If you miss any scheduled session you should contact your doctor immediately and fix an appointment as recommended by your doctor.
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Overdose
Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
Interactions
Interaction with Medicines- Dexamethasone moderate
- Atazanavir severe
- Erythromycin moderate
- Itraconazole severe
- Clozapine severe
- Linezolid moderate
- Clarithromycin severe
- Atorvastatin moderate
- Phenobarbital moderate
General Instructions
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Other details
- Usage does not depend on food timings
- To be taken as instructed by doctor
- May cause sleepiness
References
- webmd.com - Vinblastine [Internet]. Available from: https://www.webmd.com/drugs/2/drug-52/vinblastine-intravenous/details [cited 30/7/2020].
- drugs.com - Vinblastine [Internet]. Available from: https://www.drugs.com/mtm/vinblastine.html [cited 30/7/2020]. 2019
How to use Vinblas Injection 10 mg 1 Vial
IV: Vesicant. Drug is for IV administration only. Administer vinblastine IV, usually as a slow (2-3 min) push, or a bolus (5-15 min) infusion. It is occasionally given as a 24-hour continuous infusion.
Reconstitution: Reconstitute to a conc of 1 mg/mL with bacteriostatic water, bacteriostatic NS, SWFI, NS, or D5W; for infusion, may be diluted with 50-1000 mL NS or D5W.
Compatibility: Stable in D5W, LR, NS, bacteriostatic water.
what are the adverse effects of Vinblas Injection 10 mg 1 Vial?
Alopecia, SIADH, diarrhoea, anorexia, severe bone marrow suppression.
What happens if I miss a dose of Vinblas Injection 10 mg 1 Vial?
Hodgkin’s disease/lymphocytic lymphoma/ histiocytic lymphoma/advanced mycosis fungoides/advanced testicular cancer/Kaposi’s sarcoma Letterer-Siwe disease/resistant choriocarcinoma/unresponsive breast cancer: Dose IV at weekly intervals. Adults: 1st dose=3.7 mg/m², 2nd dose=5.5 mg/m², 3rd dose=7.4 mg/m², 4th dose=9.25 mg/m², 5th dose= 11.1 mg/m², increase to a max 18.5 mg/m². Children: 1st dose=2.5 mg/m², 2nd dose=3.75 mg/m², 3rd dose=5 mg/m², 4th dose=6.25 mg/m², 5th dose= 7.5 mg/m², increase to a max 12.5 mg/m². Maintenance: Dose is 1 increment smaller than when leucopenia produced.
One of the following licensed pharmacy from the nearest location will deliver Vinblas Injection 10 mg 1 Vial. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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