Vit-K1 Injection 2 mg/mL 1 Amp

How to use Vit-K1 Injection 2 mg/mL 1 Amp

Whenever possible, give by the SC route. When IV administration is considered unavoidable, inject the drug very slowly, not exceeding 1 mg/min.
Reconstitution: Dilute in NS, D5W or D5NS. All these diluents should be preservative free. Do not use other diluents.
Stability: Store at 15°C-30°C (59°F-86°F). Protect from light. Store ampoules in tray until time of use.

what are the adverse effects of Vit-K1 Injection 2 mg/mL 1 Amp?

Anaphylactoid reactions may occur with inj. Flushes, sweating, cyanosis.

What happens if I miss a dose of Vit-K1 Injection 2 mg/mL 1 Amp?

Adults: Hypoprothrombinaemia due to drugs (other than coumarin derivatives) or factors limiting absorption or synthesis: Oral/SC/IM/IV: Initially, 2.5-25 mg, rarely up to 50 mg.
Children: Neonatal prophylaxis of vitamin-K deficiency bleeding: 1 mg by single IM injection at birth. For preterm neonates: 400 micrograms/kg (max 1 mg), may be given by IV if IM not possible; since IV administration may not provide the prolonged protection of the IM injection, subsequently vitamin K should be given by oral doses. For healthy babies who are not at particular risk of bleeding disorders: Orally two doses of a colloidal (mixed micelle) preparation of phytomenadione 2 mg should be given in the first wk, the first dose being given at birth and the sec at 4-7 days. For exclusively breast-fed babies, a third dose of phytomenadione 2 mg is given at 1 mth of age; the third dose is omitted in formula-fed babies because formula feeds contain adequate vitamin K. Alternatively, one dose of 1 mg by mouth at birth to protect from the risk of vitamin K deficiency bleeding in the first wk. For exclusively breast-fed babies, further doses of phytomenadione 1 mg are given orally at wkly intervals for 12 wk.
Neonatal hypoprothrombinaemia or vitamin-K deficiency bleeding: IV injection. Neonate, 1 mg repeated 8 hourly if necessary.
Neonatal biliary atresia and liver disease: Orally. Neonate, 1 mg daily. Reversal of coumarin anticoagulation when continued anticoagulation required or if no significant bleeding: IV injection. 1 mth-18 yr, 15-30 mcg/kg (max 1 mg) as a single dose, repeated as necessary.
Reversal of coumarin anticoagulation when anticoagulation not required or if significant bleeding; treatment of haemorrhage associated with vitamin-K deficiency: IV injection. 1 mth-18 yr, 250-300 mcg/kg (max 10 mg) as a single dose.

One of the following licensed pharmacy from the nearest location will deliver Vit-K1 Injection 2 mg/mL 1 Amp. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.