₨ 3,000.00
MBBS
Vorif tablet 200 mg 10’s
- Does this requires a prescription ? Yes
- Generic Name: Voriconazole
- Manufactured by : Ferozson Laboratories Ltd.
- Drug Strength : 200 mg
- Drug Form : Tablet
- Pack Size : 10s
- Product SKU : pg_24341_33688
Vorif tablet contains Voriconazole | belongs to Triazole antifungal
Alternate brands of Vorif tablet 200 mg 10’s
| Brand Name | Price | Savings |
|---|---|---|
| Vorix Injection 200mg (voriconazole) | ₨ 4,000.00 | You will pay -1000 more |
| Vorif tablet 50 mg 10’s | ₨ 400.00 | You can save 2600 |
| Voricon tablet 200 mg 10’s | ₨ 1,100.00 | You can save 1900 |
How it works
Vorif tablet 200 mg 10’s works by slowing the growth of the fungi that cause infection.
Uses of Vorif tablet 200 mg 10’s
What is it prescribed for?
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Invasive Aspergillosis
This medicine is used in the treatment of infections in the lungs or immune system caused by Aspergillus strain of fungus.
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Esophageal Candidiasis
This medicine is used in the treatment of infections in the throat caused by Candida strain of fungus.
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Candidemia
This medicine is used in the treatment of infections of the blood caused by Candida strain of fungus.
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Fungal Pneumonia
This medicine is used in the treatment of infections that affects the lungs caused by Histoplasma capsulatum and Candida strains of fungi.
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Fusariosis
This medicine is used in the treatment of infections that affect immunocompromised patients caused by fusarium strain of fungus.
Concerns
Frequently asked questions
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Onset of action
The peak effect of this medicine can be observed in 1 to 2 hours.
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Duration of Effect
The effect of this medicine lasts for an average duration of 6 hours.
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Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
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Is it habit forming?
No habit forming tendencies were reported.
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Usage in pregnancy?
This medicine is not recommended for pregnant women unless clearly needed. Consult your doctor regarding potential benefits and risks before taking this medicine.
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Usage while breast-feeding?
Sufficient information is not available on whether this medicine is excreted through breast milk. Stop breastfeeding if it's necessary to take this medicine. Consult your doctor regarding potential benefits and risks before taking this medicine.
When not to use?
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Allergy
This medicine is not recommended for use if you have a known allergy to this medicine.
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QT Interval prolonging drugs
This medicine is not recommended for co-administration with drugs that are known to cause specific changes in heart rhythm.
Warnings
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Pregnancy
This medicine is not recommended for pregnant women unless clearly needed. Consult your doctor regarding potential benefits and risks before taking this medicine.
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Breast-feeding
Sufficient information is not available on whether this medicine is excreted through breast milk. Stop breastfeeding if it's necessary to take this medicine. Consult your doctor regarding potential benefits and risks before taking this medicine.
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Liver injury
This medicine may increase the liver enzyme levels and can cause hepatitis and jaundice. Close monitoring of liver function (through tests) is necessary at the time of initiation of the treatment. Discontinue the medicine if symptoms worsen.
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Visual Disturbances
This medicine may cause visual disturbances like optic neuritis and papilledema. Close monitoring of visual function is necessary if treatment continues beyond 28 days.
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Arrhythmia and QT Prolongation
This medicine may cause Arrhythmia and QT Prolongation especially in the patients with existing heart disease. Close monitoring of heart function is necessary. Do not use medicines that can increase the risk of arrhythmia.
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Impaired kidney function
Use of intravenous Vorif tablet 200 mg 10’s is not recommended in the patients with moderate to severe kidney injury (creatinine clearance level < 50 mL/min) due to the risk of accumulation. Oral dosage forms may be considered after assessing benefits and risks.
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Monitoring pancreas function
This medicine may increase the risk of pancreatitis in the patients who have undergone recent chemotherapy or hematopoietic stem cell transplantation. Close monitoring of the functioning of the pancreas is necessary.
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Skin reactions
This medicine may cause serious skin reactions like Stevens-Johnson syndrome or photosensitivity skin reaction. Close monitoring of skin reactions is necessary. Avoid exposure to sunlight by wearing protective clothing and using sunscreen with high sun protection factor (SPF).
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Pediatric population
The safety and effectiveness of Vorif tablet 200 mg 10’s is not established in patients who are less than 2 years of age.
Dosage
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Missed Dose
The missed dose can be taken as soon as you remember. If it is time for the next dosage then the missed dose can be skipped.
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Overdose
Inform your doctor immediately if you are experiencing symptoms of overdose.
Interactions
Interaction with Medicines- Alprazolam severe
- Cisapride severe
- Clopidogrel severe
- Warfarin moderate
- Atorvastatin severe
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Take This medicine at least 1 hour before or after food for better absorption.
General Instructions
This medicine should be taken following all the instructions that are given by your doctor. To ensure complete recovery and no relapse, the full course of treatment should be followed. It is more effective if taken at the same time on all days. Any instance of side effects should be reported to the doctor immediately.
References
- medlineplus.gov - Voriconazole [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a605022.html [cited 30/7/2020]. 2020
How to use Vorif tablet 200 mg 10’s
Reconstitute with 19 mL of SWFI and shake well to yield 20 mL of voriconazole 10 mg/mL solution. Administered by IV infusion in a compatible infusion solution at a concentration between 0.5 and 5 mg/mL over 1 to 2 hours at a max rate of 3 mg/kg/hour.
Compatibility: Dextrose 5%, NaCl 0.9%.
Stability: Reconstituted stable for 24 hours under refrigeration, use immediately after reconstitution because no antimicrobial preservative is present. Single use only and any remaining drug should be discarded.
what are the adverse effects of Vorif tablet 200 mg 10’s?
Headache, paresthesia, somnolence, GI upset, rash, visual disturbances, pyrexia, gastroenteritis, sinusitis, depression, hallucination, anxiety, tremors, agitation, chills, asthaenia, back and chest pain, inj or inf site reactions, acute respiratory distress syndrome, flu-like symptoms, hypotension, thrombophlebitis, phlebitis, raised LFTs and creatinine, jaundice, cheilitis, pruritus, alopecia, dermatitis, blood dyscrasia, purpura, erythema, hypokalaemia, hypoglycaemia, dizziness, confusion, acute renal failure, hematuria, peripheral pulmonary and facial oedema.
What happens if I miss a dose of Vorif tablet 200 mg 10’s?
INFUSION: Adults: Loading dose: For first 24 hr, 6 mg/kg by IV infusion every 12 hr. Maintenance dose: 4 mg/kg by IV infusion twice daily. If not tolerated it may be reduced to 3 mg/kg twice daily. Max infusion rate: 3 mg/kg/hr over 1-3 hr. Max treatment duration, 6 mth. Children: Under 2 yr: Not recommended; 2-12 yr: or 12-14 yr and less than 50 kg, Loading dose: For first hrs, 9 mg/kg by IV inf every 12 hrs. Maint; 8 mg/kg by IV inf twice daily. 12-14 yr and =50 kg, as adults. If response inadequate, maintenance dose may be increased in 1 mg/kg steps. If not tolerated, it may be reduced in 1 mg/kg steps. Max inf. Rate 3 mg/kg/hr over 1-3 hr. ORAL: Adults: For first 24 hr: 400 mg every 12 hr (gt;40 kg) or 200 mg every 12 hr (lt;40 kg), Maint: 200 mg twice daily (gt; than 40 kg) or 100 mg twice daily (lt;40 kg). If response inadequate it may be increased to 300 mg twice daily (gt; 40 kg) or 150 mg twice daily (lt;40 kg). A tablet should be taken 1 hr before or 1 hr after food. Children: Under 2 yr: Not recommended; 2-12 yr or 12-14 yr and body wt lt; 50 kg: Use infusion until significant improvement then 9 mg/kg twice daily. (preferred as susp lt;12 yr). Titrate if necessary in 1 mg/kg increments (50 mg increments if initial dose was 350 mg); max 350 mg twice daily; 12-14 yr and body wt lt; 50 kg, same as adults. Tab should be taken 1 hr before or 1 hr after food; susp should be taken 1 hr before or 2 hr after food.
One of the following licensed pharmacy from the nearest location will deliver Vorif tablet 200 mg 10’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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2 reviews for Vorif tablet 200 mg 10’s
Ajeet kumar –
Ajeet kumar submitted 5 stars.
Sajjad Anwar Bajwa –
excellent