MBBS
Votrient tablet 400 mg 30’s imported
Votrient tablet contains Pazopanib | belongs to Protein kinase inhibitor
Alternate brands of Votrient tablet 400 mg 30’s imported
Brand Name | Price | Savings |
---|---|---|
Votrient tablet 200 mg 30’s imported | ₨ 53,000.00 | You can save 12000 |
Votrient 400mg (Pazopanib) Tablet is a protein kinase inhibitor used in the treatment of kidney cancer and soft tissue sarcoma.
Votrient 400mg containis Pazopanib which is now available in Pakistan. The price of Votrient 400mg is Rs. 65000 as of 22nd September 2020. The prices are updated regularly on this page.
How it works
Votrient tablet 400 mg 30’s imported works by inhibiting the activity of certain proteins that are necessary for the growth and spread of cancer cells.
Side effects
Major & minor side effects for Votrient tablet 400 mg 30’s imported
- Blurred vision
- Chest pain
- Chills
- Cough
- Dizziness
- Fever
- Hair loss
- Headache
- Nausea and Vomiting
- Sore throat
- Weight gainSweating
- Sweating
- Drowsiness
Uses of Votrient tablet 400 mg 30’s imported
What is it prescribed for?
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Advanced Renal Cell Carcinoma (RCC)
This medicine is used in the treatment of advanced renal cell carcinoma, which is the most common type of kidney cancer.
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Advanced Soft Tissue Sarcoma
This medicine is used for the treatment of advanced soft tissue sarcoma, a tumor that can occur in and around joints, muscles, tendons, blood vessels, or organs.
Concerns
Frequently asked questions
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Onset of action
The amount of time required for this medicine to show its action is not clinically established.
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Duration of Effect
The amount of time for which this medicine remains active in the body is not clinically established.
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Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
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Is it habit forming?
No habit-forming tendencies were reported.
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Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
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Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.
When not to use?
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Allergy
This medicine is not recommended for use in patients with a known allergy to Votrient tablet 400 mg 30’s imported or any other inactive ingredients present along with it.
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Severe Hepatic impairment
This medicine is not recommended for use in patients with severe liver impairment due to the increased risk of worsening of the patient's condition.
Warnings
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Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
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Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.
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Kidney function impairment
This medicine should be used with caution in patients with kidney diseases, especially in case of severe kidney diseases, due to the increased risk of serious side effects. Close monitoring of kidney function tests is necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
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Driving or Operating Machinery
This medicine may cause blurred vision or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.
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Bleeding disorders
This medicine should be used with extreme caution in patients with bleeding disorders or any gastrointestinal perforations since it may increase the risk of excessive bleeding. Discontinuation of the therapy with this medicine may be required in such patients based on the clinical condition.Surgeries
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Surgeries
Use of this medicine may be stopped for at least 7 days prior to the surgical procedures because it may impair the wound healing process.
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QT Prolongation
This medicine should be used with extreme caution in patients with prolonged QT intervals due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
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Use in Children
This medicine is not recommended for use in children below 18 years of age since the safety and efficacy of use are not clinically established.
Dosage
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Missed Dose
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.
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Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose
Interactions
Interaction with Medicines- Atazanavir severe
- Adalimumab severe
- Citalopram severe
- Clozapine severe
- Amiodarone severe
- Cisapride severe
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severe
This medicine should be used with extreme caution in patients with latent or active bleeding disorders since it may increase the risk of excessive bleeding and worsen the patient's condition. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the patient's condition.
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severe
This medicine should be used with caution in patients suffering from mild to moderate liver diseases or patients at risk of liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition. This medicine is not recommended for use in patients with severe liver diseases.
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moderate
This medicine should be used with extreme caution in patients with pre-existing hypertension due to the increased risk of worsening of the patient's condition. Close monitoring of blood pressure levels, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
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moderate
This medicine should be used with caution in patients having a low level of thyroid hormone due to the increased risk of worsening of the patient's condition. Close monitoring of thyroid hormone levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
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moderate
This medicine should be used with caution in patients suffering from lung diseases due to the increased risk of worsening of the patient's condition. Close monitoring of lung function tests is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
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Consumption of grapefruit juice is not recommended during treatment with this medicine due to the increased risk of adverse effects such as liver damage, irregular heart rhythm, high blood pressure, bleeding, etc. Report any unusual symptoms such as dizziness, muscle pain, fever and chills, headache, swelling of hands and feet, vomiting, skin rash, etc. to the doctor immediately.
General Instructions
Take this medicine at least 1 hour before or 2 hours after a meal. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Other details
- To be taken on an empty stomach
- To be taken as instructed by doctor
- May cause sleepiness
References
- practo.com - Pazopanib [Internet]. Available from: https://www.practo.com/medicine-info/pazopanib-365-api [cited 24 september 2019]. 11 Jan 2019
- pubchem.ncbi.nlm.nih.gov - Pazopanib [Internet]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/Pazopanib [cited 24 september 2019]. 2019-09-21
- drugbank.ca - Pazopanib [Internet]. Available from: https://www.drugbank.ca/drugs/DB06589 [cited 24 september 2019]. September 23, 2019
- medlineplus.gov - Pazopanib [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a610013.html [cited 24 september 2019]. 11 September 2019
what are the adverse effects of Votrient tablet 400 mg 30’s imported?
Blood dyscrasias, hypothyroidism, decreased appetite, dysgeusia, headache, dizziness, lethargy, paraesthesia hypertension, hot flush, epistaxis, dysphonia, GI upset, abnormal hepatic function, hair colour. Change, skin reactions, myalgia, muscle spasms, proteinuria, fatigue, asthaenia, mucosal inflammation, oedema, chest pain, altered LFTs and blood chemistry, weight loss. Cardiac dysfunction, transient ischaemic attack, stroke, myocardial infarction, myocardial ischaemia, bradycardia, haemorrhage, hypertensive crisis, QT-interval prolongation, pulmonary embolism, peripheral neuropathy, menstrual disturbances.
What happens if I miss a dose of Votrient tablet 400 mg 30’s imported?
Adults: 800 mg once daily. Children: Not recommended.
One of the following licensed pharmacy from the nearest location will deliver Votrient tablet 400 mg 30’s imported. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
Questions and Answers
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3 reviews for Votrient tablet 400 mg 30’s imported
Asim Iqbal –
Asim Iqbal submitted 5 stars.
Siddique pervaiz –
i have not got the confirmd votrient 400 order no 355362. neither i have told about the fate of this order so much irresponcibility
Siddique pervaiz –
Siddique pervaiz submitted 5 stars.