₨ 27.00
MBBS
Xyrox tablet 250 mg 10's
- Does this requires a prescription ? Yes
- Generic Name: Erythromycin, Inj/Oral
- Manufactured by : Jawa Pharmaceuticals (PVT) LTD
- Drug Strength : 250 mg
- Drug Form : Tablet
- Pack Size : 10s
- Product SKU : pg_24769_34389
Xyrox tablet contains Erythromycin, Inj/Oral | belongs to Macrolide
Alternate brands of Xyrox tablet 250 mg 10’s
| Brand Name | Price | Savings |
|---|---|---|
| Xyrox tablet 500 mg 10’s | ₨ 52.00 | You will pay -25 more |
| Wilmycin suspension 200 mg 60 mL | ₨ 30.00 | You will pay -3 more |
| Trocin suspension 200 mg 60 mL | ₨ 39.24 | You will pay -12.24 more |
| Trocin tablet 250 mg 10×10’s | ₨ 313.50 | You will pay -286.5 more |
| Trocin tablet 250 mg Jarx100’s | ₨ 283.25 | You will pay -256.25 more |
How it works
Xyrox tablet 250 mg 10’s is used to treat bacterial infections by interfering with the bacterial protein synthesis.
Side effects
Major & minor side effects for Xyrox tablet 250 mg 10’s
- Skin blistering severe
- Chills severe
- Diarrhea severe
- Dizziness severe
- Fast heartbeat severe
- Skin rash severe
- Muscle or joint pain severe
- Chest tightness severe
- Abdominal pain
- Loss of appetite
- Weight loss
Uses of Xyrox tablet 250 mg 10’s
What is it prescribed for?
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Pneumonia
Xyrox tablet 250 mg 10’s is used in the treatment of Pneumonia which is a common type of lung infection caused by Streptococcus pneumoniae and Haemophilus influenzae.
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Ear Infection (Otitis Media)
Xyrox tablet 250 mg 10’s is used in the treatment if Otitis Media which is an ear infection caused by Streptococcus pneumoniae and Haemophilus influenzae.
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Bronchitis
Xyrox tablet 250 mg 10’s is used in the treatment of Bronchitis which is an inflammation in lungs caused by Streptococcus pneumoniae, Haemophilus influenzae, and some Mycoplasma pneumoniae.
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Pertussis
Xyrox tablet 250 mg 10’s is used in the treatment of Pertussis which is commonly referred to as whooping cough. It is caused by Bordetella pertussis.
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Prophylaxis for Rheumatic Fever
Xyrox tablet 250 mg 10’s is used as prophylaxis for rheumatic fever which is an inflammatory disease that can cause strep throat caused by streptococcus bacteria.
Concerns
Frequently asked questions
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Onset of action
The peak effect of this medicine can be observed within 3 hours of oral administration.
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Duration of Effect
The effect of this medicine lasts for an average duration of 4 to 6 hours.
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Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
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Is it habit forming?
No habit forming tendency has been reported.
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Usage in pregnancy?
Clear data is not available regarding the use of this medicine in pregnant women. Use only if the benefits outweigh the risks and if no other safer alternative is available.
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Usage while breast-feeding?
A small amount of this medicine is excreted in human breast milk. Use only if benefits outweigh the risks and if no other safer alternative is available. Monitoring of diarrhea, thrush and diaper rash is necessary.
When not to use?
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Allergy
Avoid taking this medicine if you have a known allergy to it or any other macrolides.
Warnings
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Pregnancy
Clear data is not available regarding the use of this medicine in pregnant women. Use only if the benefits outweigh the risks and if no other safer alternative is available.
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Breast-feeding
A small amount of this medicine is excreted in human breast milk. Use only if benefits outweigh the risks and if no other safer alternative is available. Monitoring of diarrhea, thrush and diaper rash is necessary.
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Allergy
Avoid taking this medicine if you have a known allergy to Xyrox tablet 250 mg 10’s or other macrolides. Seek immediate medical attention if the patient experiences any allergic symptoms like rashes, itching, nausea, vomiting, swelling of lips, hands, and feet.
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Drug-resistance
Usage of Xyrox tablet 250 mg 10’s without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that is drug resistant.
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Clostridium difficile-associated Diarrhea
Avoid if you experience severe diarrhea after receiving Xyrox tablet 250 mg 10’s . As antibiotic therapy will cause an imbalance in the normal microbial flora in the large intestine which promotes the growth of bacteria called Clostridium difficile.
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Impaired liver function
Xyrox tablet 250 mg 10’s may increase the liver enzymes and may cause cholestatic hepatitis, with or without jaundice. This medicine should be used with caution in the patients with the history of liver disease. Dose adjustments are to be made based on the severity of liver injury.
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QT prolongation
Xyrox tablet 250 mg 10’s should be used with caution in the patients receiving QT prolongation medications as it can increase the risk of arrhythmia. Frequent monitoring of heart function is necessary and an alternate medicine should be considered.
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Myasthenia Gravis
Xyrox tablet 250 mg 10’s should be used with caution in the patients with the history of Myasthenia Gravis as it may aggravate the weakness in these patients.
Dosage
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Missed Dose
The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for your next dose.
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Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
Interactions
Interaction with Medicines- Clonazepam moderate
- Amiodarone severe
- Pimozide severe
- Ethinyl Estradiol moderatee
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severe
Xyrox tablet 250 mg 10’s should be used with caution in the patients with a history of liver disease. Frequent monitoring of liver function tests is necessary. Dose adjustments are to be made based on the severity of liver injury.
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severe
Inform your doctor if you have arrhythmia, any heart disease or drugs that prolong QT interval such as psychiatric drugs and anti-arrhythmic drugs.
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moderate
Xyrox tablet 250 mg 10’s should be used with caution in the patients with the history of Myasthenia Gravis as it may aggravate the weakness in these patients. Dose adjustments or an alternate medicine should be prescribed based on the medical condition.
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Take Xyrox tablet 250 mg 10’s at least 30 minutes before or 2 hours after meals. Consumption of grapefruit juice is not recommended as it may increase the concentration of Xyrox tablet 250 mg 10’s and can cause undesired effects.
General Instructions
Take Xyrox tablet 250 mg 10’s as advised by your doctor. You may take this drug with or without food and do not take in larger amounts than advised.
Other details
- Can be taken with or without food, as advised by your doctor
- To be taken as instructed by doctor
- Does not cause sleepiness
References
- practo.com - Erythromycin [Internet]. Available from: https://www.practo.com/medicine-info/erythromycin-103-api [cited 17 september 2019]. 16 Nov 2017
- medlineplus.gov - Erythromycin [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a682381.html [cited 17 september 2019]. 11 September 2019
How to use Xyrox tablet 250 mg 10’s
IV Infusion may be very irritating to the vein. If phlebitis/pain occurs with used dilution, consider diluting further (e.g. 1:5) if fluid states of the patient will tolerate, or consider administering in larger available vein.
Reconstitution: Erythromycin lactobionate should be reconstituted with SWFI without preservatives to avoid gel formation. The reconstituted solution is stable for a weeks when refrigerated or for 24 hours at room temperature. IV form has the longest stability in 0.9% sodium chloride (NS) and should be prepared in this base solution whenever possible. Do not use D5W as a diluent unless sodium bicarbonate is added to solution. If IV must be prepared in D5W, 0.5 mL of the 8.4% sodium bicarbonate solution should be added per each 100 mL of D5W. Standard diluent: 500 mg/250 mL D5W/NS; 750 mg/250 mL D5W/NS; 1 gm/250 mL D5W/NS.
Compatibility: Stable in NS. Incompatible with D5LR, D10W.
Y-site administration: Incompatible with fluconazole.
Stability: The reconstituted solution is stable for 2 weeks when refrigerated or for 24 hours at room temperature. Stability of parenteral admixture at room temperature (25°C) and at refrigeration temperature (4°C) is 24 hours.
what are the adverse effects of Xyrox tablet 250 mg 10’s?
GI upset, cholestatic jaundice, allergic reactions, reversible hearing loss, pancreatitis, cardiac effects, myasthaenia-like syndrome, Stevens-Johnson syndrome, toxic epidermal necrolysis, hepatotoxicity, hypotension, interstitial nephritis, hallucinations, chest pain, fever, malaise, QT prolongation, infantile hypertrophic pyloric stenosis, C.difficile associated diarrhoea.
What happens if I miss a dose of Xyrox tablet 250 mg 10’s?
ORAL: Adults: 250-500 mg every 6 hr or 500 mg-1 gm every 12 hr taken before or with meals; up to 4 gm daily in divided doses in severe infections. Children: Neonate: 12.5 mg/kg every 6 hr; 1 mth-2 yr, 125 mg every 6 hr; 2-8 yr, 250 mg every 6 hr. The dosage doubled for severe infection.
Lower Respiratory Infection: Adults: Usual: 250 mg every 6 hr or 500 mg every 12 hr. Children: Usual: 30-50 mg/kg/day in divided doses. Max: 4 gm/day.
Upper Respiratory Infection: Adults: Usual: 250 mg every 6 hr or 500 mg every 12 hr. Children: Usual: 30-50 mg/kg/day in divided doses. Max: 4 gm/day.
Skin Infections: Adults: Usual: 250 mg every 6 hr or 500 mg every 12 hr. Children: Usual: 30-50 mg/kg/day in divided doses. Max: 4 gm/day.
Acne: Initially 250 mg twice daily; maintenance 250 mg once daily after one mth.
Early syphilis: Adults: Usual: 500 mg every 6 hr for 14 days.
Uncomplicated genital chlamydia, non-gonococcal urethritis: 500 mg every 12 hr for 14 days.
Lyme disease: 500 mg every 6 hr for 14-21 days.
INJECTION: By IV infusion. Adults & Children: 12.5 mg/kg every 6 hr in severe infection; 6.25 mg/kg every 6 hr in mild infection when oral treatment not possible, max 4 gm/day in severe infections. Neonate: 20 mg/kg/day to 30 mg/kg/day in 2-3 divided doses (see literature).
One of the following licensed pharmacy from the nearest location will deliver Xyrox tablet 250 mg 10’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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