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Information on this page was last modified on : 2024/06/01 5:20:15 PM

YONDELIS 1 MG IV

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How It Works

YONDELIS contains the active ingredient trabectedin, which is a marine-derived alkaloid with antitumor activity. Trabectedin binds to the minor groove of DNA, causing DNA strand breaks and interfering with DNA transcription and replication processes in cancer cells. This leads to cell cycle arrest and apoptosis (programmed cell death) of cancer cells, ultimately inhibiting tumor growth.

Side Effects

  • Nausea
  • Vomiting
  • Fatigue
  • Anemia
  • Neutropenia (low white blood cell count)
  • Thrombocytopenia (low platelet count)
  • Elevated liver enzymes

Indications

  • YONDELIS is indicated for the treatment of:
    • Advanced soft tissue sarcoma (STS) in patients who have received prior chemotherapy
    • Liposarcoma or leiomyosarcoma that cannot be removed by surgery or has spread to other parts of the body

Contraindications

  • Hypersensitivity to trabectedin or any component of the formulation
  • Severe hepatic impairment

Price Comparison in Different Countries

Country Price (per vial) Website
United States $1,500 GoodRx
United Kingdom £1,200 NHS
Australia AUD 1,800 Chemist Warehouse
Canada CAD 1,600 Canada Drugs Direct
Germany €1,300 Apotheken Umschau

Top 5 Global Brands

  1. PharmaMar
  2. Janssen Pharmaceuticals
  3. Johnson & Johnson
  4. Marine Pharma BV
  5. Chugai Pharmaceutical Co., Ltd.

 

Additional Information:

One of the following licensed pharmacy from the nearest location will deliver YONDELIS 1 MG IV. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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