Content Details

Dr. Waqar Younus
MBBS
Information on this page was last modified on : 2024/06/01 5:20:15 PM
YONDELIS 1 MG IV
Belongs to CategoryMedicine & Health
How It Works
YONDELIS contains the active ingredient trabectedin, which is a marine-derived alkaloid with antitumor activity. Trabectedin binds to the minor groove of DNA, causing DNA strand breaks and interfering with DNA transcription and replication processes in cancer cells. This leads to cell cycle arrest and apoptosis (programmed cell death) of cancer cells, ultimately inhibiting tumor growth.
Side Effects
- Nausea
- Vomiting
- Fatigue
- Anemia
- Neutropenia (low white blood cell count)
- Thrombocytopenia (low platelet count)
- Elevated liver enzymes
Indications
- YONDELIS is indicated for the treatment of:
- Advanced soft tissue sarcoma (STS) in patients who have received prior chemotherapy
- Liposarcoma or leiomyosarcoma that cannot be removed by surgery or has spread to other parts of the body
Contraindications
- Hypersensitivity to trabectedin or any component of the formulation
- Severe hepatic impairment
Price Comparison in Different Countries
Country | Price (per vial) | Website |
---|---|---|
United States | $1,500 | GoodRx |
United Kingdom | £1,200 | NHS |
Australia | AUD 1,800 | Chemist Warehouse |
Canada | CAD 1,600 | Canada Drugs Direct |
Germany | €1,300 | Apotheken Umschau |
Top 5 Global Brands
- PharmaMar
- Janssen Pharmaceuticals
- Johnson & Johnson
- Marine Pharma BV
- Chugai Pharmaceutical Co., Ltd.
Additional Information:
One of the following licensed pharmacy from the nearest location will deliver YONDELIS 1 MG IV. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
Want to share this information?
Facebook
Twitter
LinkedIn
Something doesn't feel right ?
Questions and Answers
There are no questions yet. Be the first to ask a question about this product.
Only registered users are eligible to enter questions
Reviews
There are no reviews yet.