₨ 5,033.60
MBBS
ZAVEDOS 5mg Injection Vial
- Does this requires a prescription ? Yes
- Generic Name: Idarubicin (HCl):5mg
- Manufactured by : Pfizer
- Drug Strength : 5mg
- Drug Form : Injection
- Pack Size : Vial
- Product SKU : dis_20618
Idarubicin (HCl):5mg | Cytotoxic (anti-neoplastic) drugs
Manufactured / Marketed By : Pfizer Product Form : InjectionPack Size : VialIngredients : Idarubicin (HCl):5mgGeneric Category : Cytotoxic (anti-neoplastic) drugs
How it works
ZAVEDOS 5mg Injection Vial works by slowing or stopping the growth of cancer cells in your body.
Side effects
Major & minor side effects for ZAVEDOS 5mg Injection Vial
- Headache
- Chills and fever
- Hair loss or thinning of the hair
- Loss of appetite
- Nausea and vomiting
- Red colored urine
- Skin rash and itching
- Darkening of skin
- Tiredness and weakness
Uses of ZAVEDOS 5mg Injection Vial
What is it prescribed for?
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Acute Lymphocytic Leukemia (ALL)
The medicine is used as a second line treatment of relapsed acute lymphocytic leukemia, a type of cancer of the blood and bone marrow which affects the white blood cells (lymphocytes).
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Acute Myeloid Leukemia
This medicine is used in the treatment of a type of cancer of the blood and bone marrow which affects the red blood cells, platelets, and all white blood cells except lymphocytes.
Concerns
Frequently asked questions
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Onset of action
The amount of time required for this medicine to show its action is not clinically established.
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Duration of Effect
The amount of time for which this medicine remains active in the body is not clinically established.
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Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
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Is it habit forming?
No habit-forming tendencies were reported.
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Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking/receiving this medicine.
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Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking/receiving this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.
When not to use?
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Allergy
This medicine is not recommended for use if you have a known allergy to ZAVEDOS 5mg Injection Vial or any other ingredients present along with it.
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Severe liver impairment
This medicine is not recommended for use in patients with severe liver impairment due to the increased risk of worsening of the patient's condition.
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Severe and uncontrolled infections
This medicine is not recommended for use in patients who have severe and uncontrolled infections due to the increased risk of worsening of the patient's condition.
Warnings
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Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking/receiving this medicine.
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Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking/receiving this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.
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Bonemarrow suppression
This medicine should be used with caution in patients having conditions like thrombocytopenia, agranulocytosis, anemia, or bone marrow suppression due to the increased risk of worsening of the patient's condition. A complete blood count should be performed before initiating treatment with this medicine. Close monitoring of blood counts is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
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Risk of infections
Use of this medicine may weaken the immune system and may make you more vulnerable to infections. It is advised that you avoid coming in contact with people suffering from an infection while receiving this medicine.
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Driving or Operating machinery
Use of this medicine may cause dizziness, tiredness, etc. in some patients. Hence, it is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery if you experience any of these symptoms during treatment with this medicine.
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Hyperuricemia
This medicine may elevate the blood uric acid levels in some patients. Close monitoring of blood uric acid levels is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
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Effect on heart
This medicine may increase the risk of toxic effects on the heart and could lead to severe adverse effects. Patients with a history of heart diseases need close monitoring while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
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Liver impairment
This medicine should be used with extreme caution in patients suffering from liver diseases due to the increased risk of worsening of the patient's condition. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient. This medicine is not recommended for use in patients with serum bilirubin greater than 5 mg/dL.
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Kidney impairment
This medicine should be used with extreme caution in patients suffering from kidney diseases due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient. This medicine is not recommended for use in patients with severe kidney impairment.
Dosage
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Missed Dose
Injection: Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low. If you miss any scheduled session, contact your doctor immediately for further instructions. Capsule: Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
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Overdose
Injection: Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected. Capsule: Seek emergency medical treatment or contact the doctor in case of an overdose.
Interactions
Interaction with Medicines- Calcium channel blockers moderate
- Live attenuated vaccines and related products severe
- Azathioprine moderate
- Clozapine severe
- Cyclosporine moderate
- Atorvastatin moderate
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severe
This medicine should be used with caution in patients having conditions like thrombocytopenia, agranulocytosis, anemia, or bone marrow suppression due to the increased risk of worsening of the patient's condition. A complete blood count should be performed before initiating treatment with this medicine. Close monitoring of blood counts is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
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severe
This medicine should be used with caution in patients having a disease of the heart due to the increased risk of worsening of the patient's condition. Close monitoring of heart function is recommended for such patients. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.
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severe
This medicine should be used with extreme caution in patients suffering from liver diseases due to the increased risk of worsening of the patient's condition. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient. This medicine is not recommended for use in patients with serum bilirubin greater than 5 mg/dL.
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severe
This medicine should be used with extreme caution in patients suffering from kidney diseases due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient. This medicine is not recommended for use in patients with severe kidney impairment.
General Instructions
Injection: This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine. Capsule: Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Do not stop the use of this medicine without consulting your doctor.
Other details
- Can be taken with or without food, as advised by your doctor
- To be taken as instructed by doctor
- May cause sleepiness
References
- medlineplus.gov - Idarubicin [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a691004.html [cited 1/9/2020]. 2020
One of the following licensed pharmacy from the nearest location will deliver ZAVEDOS 5mg Injection Vial. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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