₨ 200.00
MBBS
Zeblexin capsule 250 mg 10’s
- Does this requires a prescription ? Yes
- Generic Name: Levofloxacin, Inf/Oral
- Manufactured by : Zeb Laboratories
- Drug Strength : 250 mg
- Drug Form : Capsule
- Pack Size : 10s
- Product SKU : pg_24930_34616
Zeblexin capsule contains Levofloxacin, Inf/Oral | belongs to Quinolone
Alternate brands of Zeblexin capsule 250 mg 10’s
| Brand Name | Price | Savings |
|---|---|---|
| Zevilox tablet 500 mg 10’s | ₨ 280.00 | You will pay -80 more |
| Zevilox tablet 250 mg 10’s | ₨ 160.00 | You can save 40 |
| Zeblexin capsule 500 mg 10’s | ₨ 330.00 | You will pay -130 more |
| Xeflox Infusion IV 500 mg 1 Vialx100 mL | ₨ 195.00 | You can save 5 |
| Xalvo tablet 500 mg 10’s | ₨ 416.00 | You will pay -216 more |
How it works
Zeblexin capsule 250 mg 10’s works by inhibiting an enzyme required for the bacterial DNA to replicate, thus inhibiting bacterial cell division.
Side effects
Major & minor side effects for Zeblexin capsule 250 mg 10’s
- Diarrhea severe
- Abdominal pain severe
- Confusion severe
- Fever severe
- Redness of skin severe
- Change in taste
- Constipation
- Dizziness
- Headache
- Nausea or vomiting
Uses of Zeblexin capsule 250 mg 10’s
What is it prescribed for?
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Cystitis
Zeblexin capsule 250 mg 10’s is used in the treatment of Cystitis which is a bladder infection caused by E.coli, Pseudomonas aeruginosa, Enterococci, and Klebsiella pneumoniae.
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Pyelonephriits
Zeblexin capsule 250 mg 10’s is used in the treatment of Pyelonephritis which is a type of kidney infection caused by E.coli, Pseudomonas aeruginosa, Enterococci, and Klebsiella pneumoniae.
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Nongonococcal Urethritis
Zeblexin capsule 250 mg 10’s is used in the treatment of Nongonococcal Urethritis which is an inflammation of urethra caused by E.coli, Pseudomonas aeruginosa, and Klebsiella.
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Skin and structure Infection
Zeblexin capsule 250 mg 10’s is used in the treatment of Skin and Structure infection like cellulitis, wound infection, and cutaneous abscess caused by Streptococcus pyogenes and Staphylococcus aureus.
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Pneumonia
Zeblexin capsule 250 mg 10’s is used in the treatment of community-acquired pneumonia which is a most common type of lung infection caused by Streptococcus pneumoniae and Haemophilus influenzae.
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Bronchitis
Zeblexin capsule 250 mg 10’s is used in the treatment of bronchitis which is an inflammation of the lungs caused by Streptococcus pneumoniae, Haemophilus influenzae, and some Mycoplasma pneumoniae.
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Inhalation Anthrax
Zeblexin capsule 250 mg 10’s is used in the treatment of anthrax which is a rare but serious bacterial illness caused by Bacillus anthracis.
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Plague
Zeblexin capsule 250 mg 10’s is used in the treatment of anthrax which is a rare but serious bacterial illness caused by Bacillus anthracis.
When not to use?
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Allergy
This medicine is not recommended for use if you have a known allergy to Zeblexin capsule 250 mg 10’s or any other fluoroquinolones.
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Tendinitis or tendon rupture
This medicine is not recommended for use if you have a past history of tendinitis or tendon rupture after using Zeblexin capsule 250 mg 10’s or any other fluoroquinolones.
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Myasthenia gravis
This medicine is not recommended for use if you have a past history of myasthenia gravis or family history of myasthenia gravis (weakness and rapid tiring of muscles which are under voluntary control).
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Tendinitis and Tendon ruputure
Use of Zeblexin capsule 250 mg 10’s will increase the risk to develop tendinitis or tendon rupture during the treatment or several months after treatment. This may affect your shoulders, hands, ankles, or other parts of your body. You are at a higher risk if you are more than 60 years of age or if you have undergone a transplant of kidney, heart, or lung. You are also at a higher risk if you are on corticosteroids like dexamethasone, methylprednisolone, or prednisone.
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Drug-resistance
Usage of Zeblexin capsule 250 mg 10’s without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.
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Alternative treatment
Zeblexin capsule 250 mg 10’s can be used to treat acute bacterial exacerbation of chronic bronchitis or uncomplicated cystitis, but only as a last resort. This drug should be used only if you have no alternative treatment options for the above-mentioned conditions.
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Photosensitivity
This medicine may make you more sensitive to sunlight or tanning lights. You are advised to use sunscreen and wear protective clothing to avoid adverse reactions to sunlight during treatment with this medicine.
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Driving or Operating machinery
Use of this medicine may cause symptoms such as blurred vision, confusion, dizziness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.
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Diarrhea
Antibiotic therapy will cause an imbalance in the normal microbial flora of the large intestine, which may promote the growth of a bacteria called Clostridium difficile and you may experience severe diarrhea as a result. Report any such incidence to the doctor on priority and avoid usage of this medicine in such cases.
Dosage
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Missed Dose
The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already the time for your next scheduled dose.
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Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
Interactions
Interaction with Medicines- Escitalopram severe
- Ethinyl Estradiol moderate
- Corticosteroids severe
- Quinidine severe
- Aspirin moderate
- Antidiabetic drugs moderate
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severe
This medicine should be used with extreme caution in patients with a history of seizure disorder and other central nervous system abnormalities. Report any incidence of tremors, restlessness, anxiety, confusion, hallucinations, etc., to the doctor on priority. It is advisable to avoid using caffeine-containing products while on therapy with fluoroquinolones.
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severe
This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis. Inform your doctor if you have any history of gastrointestinal diseases. Report any incidence of severe diarrhoea, abdominal pain, and blood in stools to the doctor immediately.
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severe
This medicine should be used with extreme caution in patients with a history of heart diseases and electrolyte disturbances, especially elderly patients. Report any incidence of discomfort in the chest, heart palpitations, etc., to the doctor on priority. Regular cardiac function tests are to be performed if you have any heart disease (arrhythmia) or family history of heart disease.
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moderate
This medicine should be used with caution in patients with renal diseases due to the increased risk of severe adverse effects. Report any unusual symptoms to the doctor immediately. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
General Instructions
Take Zeblexin capsule 250 mg 10’s with or without food. Do not take in larger amounts than advised. Consult the doctor if you experience any undesirable effects. Do not stop taking Zeblexin capsule 250 mg 10’s before completion of the course.
Other details
- Can be taken with or without food, as advised by your doctor
- To be taken as instructed by doctor
- Does not cause sleepiness
References
- practo.com - Levofloxacin [Internet]. Available from: https://www.practo.com/medicine-info/levofloxacin-161-api [cited 28 August 2019]. 18 April 2018
- medlineplus.gov - Levofloxacin [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a697040.html [cited 28 August 2019]. 22 July 2019
- drugs.com - Levofloxacin [Internet]. Available from: https://www.drugs.com/mtm/levofloxacin.html [cited 28 August 2019]. 1 August 2019
- medscape.com - levofloxacin [Internet]. Available from: https://reference.medscape.com/drug/levaquin-levofloxacin-systemic-levofloxacin-342532#0 [cited 28 August 2019]. N/A
How to use Zeblexin capsule 250 mg 10’s
IV: Infuse IV solution over 60 min. Too rapid infusion can lead to hypotension. Avoid administration through an intravenous line with a solution containing multivalent cations (i.e., magnesium, calcium).
Compatibility: Stable in D5LR, D5NS, D5W, NS; incompatible with mannitol 20%, sodium bicarbonate 5%.
Y-site administration:
Drug to Drug IV Compatibility: Amikacin, aztreonam, bumetanide, calcium gluconate, cefepime, ceftriaxone, cimetidine, dexamethasone, diltiazem, diphenhydramine, dobutamine, dopamine, enalapril, epinephrine, esmolol, famotidine, fentanyl, fluconazole, gentamicin, hydrocortisone, hydromorphone, imipenem, labetalol, linezolid, magnesium sulphate, methylprednisolone, metoclopramide, metronidazole, midazolam, morphine, ondansetron, phenylephrine, tobramycin, vancomycin.
Drug to Drug IV Incompatibility: Acyclovir, alprostadil, amiodarone, azithromycin, cephazolin, furosemide, heparin, indomethacin, insulin regular, lansoprazole, nitroglycerin, sodium nitroprusside, pantoprazole, piperacillin/tazobactam, propofol, ranitidine.
Stability: Stable for 72 hours when diluted to 5 mg/mL in a compatible IV fluid. Store at room temperature. Stable for 14 days when stored under refrigeration. Stable for 6 months when frozen. Do not refreeze.
what are the adverse effects of Zeblexin capsule 250 mg 10’s?
GI upset, raised liver enzymes, tendon disorders (discontinue), insomnia, headache, dizziness, anorexia, dysgeusia, dyspnoea, arthralgia, myalgia, tinnitus, asthenia, pyrexia, reports of visual disturbances, hepatic injury, severe skin disorders, peripheral neuropathy (discontinue).
What happens if I miss a dose of Zeblexin capsule 250 mg 10’s?
Lower Respiratory Infection: Adults: 500 mg orally or IV once daily for 7-14 days or 750 mg orally or IV once daily for 5 days.
Nosocomial Pneumonia: Adults: 750 mg orally or IV once daily for 7-14 days.
Upper Respiratory Infection: Sinusitis: Adults: 500 mg orally or IV once daily for 10-14 days or 750 mg orally or IV once daily for 5 days.
Skin Infection: Adults: Uncomplicated: 500 mg orally or IV once daily for 7-10 days. Complicated: 750 mg orally or IV once daily for 7-14 days.
Urinary Tract Infection: Adults: Complicated UTI/Acute Pyelonephritis: 250 mg orally or IV once daily for 10 days. Uncomplicated UTI: 250 mg orally or IV once daily for 3 days. Chronic Bacterial Prostatitis: 500 mg orally or IV once daily for 28 days.
Children: Not recommended.
One of the following licensed pharmacy from the nearest location will deliver Zeblexin capsule 250 mg 10’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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