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Zepro tablet 250 mg 10's

Belongs to Category,

Zepro tablet contains Ciprofloxacin, Inf/Oral | belongs to Quinolone

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How it works

[post-title] works by inhibiting an enzyme required for the bacteria to make its own copies and cause serious infections.

Side effects

Major & minor side effects for Zepro tablet 250 mg 10’s

  • Diarrhea sevre
  • Abdominal pain sevre
  • White patches in the mouth or on the tongue sevre
  • Joint pain sevre
  • Black or tarry stools sevre
  • Fever with chills sevre
  • Chest tightness sevre
  • Ringing or buzzing in the ears sevre
  • Muscle pain sevre
  • Numbness of the hands sevre
  • Swelling of face, lips, eyelids, tongue, hands and feet sevre
  • Running nose
  • Sneezing

Uses of Zepro tablet 250 mg 10’s

What is it prescribed for?

  • Pneumonia

    Zepro tablet 250 mg 10’s is used in the treatment of Community-Acquired Pneumonia which is a most common type of lung infection caused by Streptococcus pneumoniae or Haemophilus influenzae.

  • Bronchitis

    Zepro tablet 250 mg 10’s is used in the treatment of bronchitis which is an inflammation of the lining of the bronchial tubes caused by Streptococcus pneumoniae, Haemophilus influenzae, and some Mycoplasma Pneumonia.

  • Pyelonephritis

    Zepro tablet 250 mg 10’s is used in the treatment of Pyelonephritis which is a type of kidney infection caused by E.coli, Pseudomonas aeruginosa, Enterococci and Klebsiella pneumoniae.

  • Cystitis

    Zepro tablet 250 mg 10’s is used in the treatment of cystitis which is a bladder infection caused by E.coli, Pseudomonas aeruginosa, Enterococci and Klebsiella pneumoniae.

  • Prostatitis

    Zepro tablet 250 mg 10’s is used in the treatment of Prostatitis (inflammation of the prostate gland that produces semen) caused by Escherichia coli, Pseudomonas and Enterococcus species.

  • Gonococcal infection

    Zepro tablet 250 mg 10’s is used in the treatment of Gonococcal infection which is a sexually transmitted bacterial infection caused by Neisseria gonorrhoeae.

  • Joint infection

    Zepro tablet 250 mg 10’s is used in the treatment of bone and joint infections caused by Enterobacter cloacae, Pseudomonas aeruginosa.

  • Pneumonia with cystic fibrosis

    Zepro tablet 250 mg 10’s is used in the treatment of Pneumonia with Cystic Fibrosis (an inherited disease that causes thick mucus to build up in the lungs and promotes the growth of bacteria like Staphylococcus aureus and Hemophilus influenzae).

Concerns

Frequently asked questions

  • Onset of action

    The peak effect of this medicine can be observed within 1 to 2 hours of administration of the dose.

  • Duration of Effect

    The effect of this medicine lasts for an average duration of 12 to 20 hours.

  • Safe with Alchohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    No habit forming tendency has been reported.

  • Usage in pregnancy?

    Use of this medicine is not recommended in pregnant women. Use only if clearly needed under the supervision of the doctor.

  • Usage while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

When not to use?

  • Allergy

    This medicine is not recommended for use if you have a known allergy to Zepro tablet 250 mg 10’sor any other medicines belonging to the class fluoroquinolones.

  • Tendinitis or tendon rupture

    This medicine is not recommended for use if you have a past history of tendinitis or tendon rupture after using Zepro tablet 250 mg 10’s.

  • Myasthenia gravis

    This medicine is not recommended for use if you have a past history or family history of Myasthenia Gravis (weakness and rapid fatigue of muscles under voluntary control).

Warnings

Warnings for special population
  • Pregnancy

    Use of this medicine is not recommended in pregnant women. Use only if clearly needed under the supervision of the doctor.

  • Breast-feeding

    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Warnings

Warnings for special population
  • Tendinitis and tendon rupture

    Use of Zepro tablet 250 mg 10’s will increase the risk to develop tendinitis or tendon rupture during the treatment or several months after treatment. It will affect the shoulder, hand, the back of your ankle, or other parts of your body. The risk is more if you are above 60 years of age and have a history of kidney, heart, or lung transplant and joint disease. You are also at high risk if you are on corticosteroids like dexamethasone, methylprednisolone or prednisone.

  • Drug-resistance

    Usage of Zepro tablet 250 mg 10’s without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that is drug resistant.

  • Alternative treatment

    Zepro tablet 250 mg 10’s will increase the risk of developing serious side effects. It should reserved for use only if you have no alternative treatment options for acute bacterial exacerbation of chronic bronchitis or uncomplicated cystitis.

Dosage

  • Missed Dose

    Oral forms: The missed dose of Zepro tablet 250 mg 10’s should be taken as soon as possible. It is advisable to skip the missed dose if it is already the time for your next scheduled dose. Do not double the dose to make up for the missed dose. Since Zepro tablet 250 mg 10’s injection is mostly administered by a healthcare professional in a clinical setting, the likelihood of missing a dose is very low.

  • Overdose

    Oral forms: Seek emergency medical attention or contact your doctor in case of an overdose with Zepro tablet 250 mg 10’s. Injection: Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

Interactions

Interaction with Medicines
  • Escitalopram severe
  • Ethinyl Estradiol moderate
  • Corticosteroids severe
  • Quinidine severe
  • Aspirin moderate
  • Antidiabetic medicines moderate
Disease interactions
  • severe

    Use of vin patients with CNS disorders may experience tremors, restlessness, anxiety, confusion and hallucinations. It is advised not to take caffeine-containing products like coffee, chocolates and energy drinks while on treatment with this medicine.

  • severe

    It is not recommended to take Zepro tablet 250 mg 10’sif you experience severe diarrhea, abdominal pain, and blood in stools after taking the medicine. Inform the doctor if you have any gastrointestinal diseases. Drink adequate amount of water to prevent dehydration.

  • severe

    Use of Zepro tablet 250 mg 10’s is not recommended if you experience any chest discomfort. Regular cardiac function tests are to be performed if you have any heart disease (arrhythmia) or family history of heart disease.

General Instructions

Oral forms: Take Zepro tablet 250 mg 10’s as advised by your doctor. You may take this medicine with or without food. Do not take in larger amounts than advised. Injection: [post-title] should be administered by a trained healthcare professional as per the doctor's instructions for only the prescribed duration only after a test dose. Inform the incidence of any adverse effects to the doctor immediately.

Other details

  • To be taken on an empty stomach
  • To be taken as instructed by doctor
  • May cause sleepiness

References

How to use Zepro tablet 250 mg 10’s

IV: Administer by slow IV infusion over 60 min into a large vein to reduce the risk of venous irritation (burning, pain, erythema and swelling); final concentration for administration should not exceed 2 mg/mL.
Reconstitution: Injection, vial: May be diluted with NS, D5W, SWFI, D10W, D5¼NS, D5½ NS, LR.
Compatibility: Stable in D5¼NS, D5½NS, D5W, D10W, LR, NS.
Y-site administration:
Drug to Drug IV Compatibility: Amikacin, amiodarone, aztreonam, calcium gluconate, cisatracurium, digoxin, diltiazem, diphenhydramine, dobutamine, dopamine, fluconazole, gentamicin, hydromorphone, linezolid, lorazepam, metoclopramide, metronidazole, midazolam, milrinone, norepinephrine, ondansetron, ranitidine, tobramycin, vasopressin.
Drug to Drug IV Incompatibility: Acyclovir, aminophylline, ampicillin/sulbactam, azithromycin, cefepime, dexamethasone sodium phosphate, furosemide, heparin, hydrocortisone sodium succinate, lansoprazole, magnesium sulphate, methylprednisolone sodium succinate, pantoprazole, phenytoin, piperacillin/tazobactam, propofol, warfarin.
When admixed: Incompatible with aminophylline, clindamycin, floxacillin, heparin.
Stability: Vial; Store between 5°C-30°C. Premixed infusion; Store between 5°C-30°C. Protect from light. Avoid freezing.

what are the adverse effects of Zepro tablet 250 mg 10’s

Nausea, diarrhoea, rash. Hypersensitivity/skin reactions; discontinue if occur. Very rarely, tendon inflammation and rupture, pseudomembranous colitis; discontinue if tendinitis or persistent diarrhoea develops. Injection: Local reaction.

What is the dose of Zepro tablet 250 mg 10’s

ORAL: Adults: 250-750 mg bid usually for 1-2 wk depending on severity and response.
Lower RTI: Mild-Moderate: 500 mg bid x 1-2 wk. Severe: 750 mg bid or 500 mg t.i.d x 1-2 wk.
Bone Infection: Mild-Moderate: 500 mg bid x 4-6 wk. Severe: 750 mg bid x 4-6 wk.
Skin Infection: Mild-Moderate: 500 mg bid x 1-2 wk. Severe: 750 mg bid x 1-2 wk.
UTI: Acute Uncomplicated: 100 mg or 250 mg bid x 3 days. Mild/Moderate: 250 mg bid x 1-2 wk. Severe/Complicated: 500 mg bid x 1-2 wk.
Acute uncomplicated cystitis: 250-500 mg bid x 3 days.
Gonorrhoea, Inhalation anthrax: 500 mg bid x 60 days after confirmed or suspected exposure.
Children: Used only for established following indication and when no other safe alternative available.
Acute exacerbation of cystic fibrosis: Under 5 yr, not recommended; 5-17 yr, 20 mg/kg bid x 10-14 days; max 750 mg/dose.
Other severe infections 20 mg/kg bid; max 750 mg/dose.
Complicated UTI/Pyelonephritis: 1-17 yr: 10-20 mg/kg bid x 10-21 days. Max: 750 mg.
Inhalation anthrax: 10-15 mg/kg bid x 60 days after confirmed or suspected exposure, max 500 mg/dose.
INJECTION: Adults: 400 mg bid or tid times daily by IV infusion over 60 min x 5-14 days depending upon the severity of infection.
Lower RTI: 400 mg IV bid x 1-2 wk. Severe: 400 mg IV tid x 1-2 wk.
Bone Infection: Mild to moderate: 400 mg IV bid x 4-6 wk. Severe: 400 mg IV tid x 4-6 wk.
Skin Infection: Mild-Moderate: 400 mg IV bid x 1-2 wk. Severe: 400 mg IV tid x 1-2 wk.
UTI: Mild/Moderate: 200 mg IV bid x 1-2 wk. Severe/Complicated: 400 mg IV bid x 1-2 wk.
Mild/Moderate Chronic Bacterial Prostatitis: 400 mg IV bid x 4 wk.
Children: Complicated UTI/Pyelonephritis: 1-17 yr: 6-10 mg/kg IV bid x 10-21 days. Max: 400 mg IV/dose.

One of the following licensed pharmacy from the nearest location will deliver Zepro tablet 250 mg 10’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts the your request based on valid prescription and availability.

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