₨ 75.00
MBBS
Zipenta Injection 500 mg 1 Vial
- Does this requires a prescription ? Yes
- Generic Name: Ceftazidime
- Manufactured by : ZAFA PHARMACEUTICAL LABORATORIES (PVT) LTD.
- Drug Strength : 500 mg
- Drug Form : Injection
- Pack Size : 1 vial
- Product SKU : pg_25189_35050
Zipenta Injection contains Ceftazidime | belongs to Cephalosporin
Alternate brands of Zipenta Injection 500 mg 1 Vial
| Brand Name | Price | Savings |
|---|---|---|
| Zitum Injection 500 mg 1 Vial | ₨ 180.00 | You will pay -105 more |
| Zitum Injection 250 mg 1 Vial | ₨ 115.00 | You will pay -40 more |
| Zitum Injection 1 gm 1 Vial | ₨ 295.00 | You will pay -220 more |
| Zipenta Injection 1 gm 1 Vial | ₨ 120.00 | You will pay -45 more |
| Zipenta Injection 250 mg 1 Vial | ₨ 42.00 | You can save 33 |
How it works
Zipenta Injection 500 mg 1 Vial is a broad spectrum antibiotic. It works by interfering with the bacterial cell wall synthesis.
Side effects
Major & minor side effects for Zipenta Injection 500 mg 1 Vial
- Abdominal pain severe
- Bloating severe
- Diarrhea severe
- Fever severe
- Swelling and redness at the injection site severe
- White patches in the mouth or on the tongue severe
- Dizziness rare
- Fast heartbeat rare
- Headache rare
- Skin rash rare
- Yellow colored eyes or skin rare
Uses of Zipenta Injection 500 mg 1 Vial
What is it prescribed for?
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Bacterial Meningitis
Zipenta Injection 500 mg 1 Vial is used in the treatment of meningitis, which is an inflammation of the protective membranes that surround the brain and spinal cord, caused by Streptococcus pneumoniae and Neisseria meningitidis.
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Bacterial Septicemia
Zipenta Injection 500 mg 1 Vial is used in the treatment of septicemia which is an infection of the blood caused by Staphylococci and Streptococcus pyogenes.
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Intra-abdominal Infection
Zipenta Injection 500 mg 1 Vial is used in the treatment of intra-abdominal infections caused by Helicobacter pylori, Staphylococci, and Streptococci.
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Pneumonia
Zipenta Injection 500 mg 1 Vial is used in the treatment of pneumonia which is a common type of lung infection caused by Streptococcus pneumoniae, and Haemophilus influenzae.
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Bone and joint infections
Zipenta Injection 500 mg 1 Vial is used in the treatment of bone and joint infections like septic arthritis and osteomyelitis caused by Staphylococci and Streptococci species.
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Pyelonephriits
Zipenta Injection 500 mg 1 Vial is used in the treatment of Pyelonephritis which is a type of kidney infection caused by E.coli, Pseudomonas aeruginosa, Enterococci and Klebsiella pneumoniae.
When not to use?
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Allergy
Avoid if the patient has a known allergy toZipenta Injection 500 mg 1 Vial or any other Beta-lactam antibiotics like penicillins and cephalosporins.
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Allergy
Avoid if you have a known allergy to Zipenta Injection 500 mg 1 Vial or Beta-lactam Antibiotics like penicillins and cephalosporins. Seek immediate medical attention if the patient experiences any allergic symptoms like rash, itching, nausea, vomiting and swelling of lips, hands or feet.
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Drug-resistance
Usage of Zipenta Injection 500 mg 1 Vial without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that is drug resistant.
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Clostridium difficile-associated Diarrhea
Avoid if you experience severe diarrhea after receiving Zipenta Injection 500 mg 1 Vial . As antibiotic therapy will cause an imbalance in the normal microbial flora in the large intestine which promotes the growth of bacteria called clostridium difficile.
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Impaired kidney function
Use with caution if you have a preexisting kidney disease. Appropriate dose adjustments are to be made based of CrCl or eGFR.
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Neurotoxicity
Zipenta Injection 500 mg 1 Vial may increase the risk of serious adverse effects like encephalopathy, seizures, and nonconvulsive status epilepticus. These reactions may occur in the patient with impaired kidney function with no proper dose adjustment.
Dosage
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Missed Dose
The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.
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Overdose
Seek emergency medical treatment or contact the doctor in case of overdose.
Interactions
Interaction with Medicines- Amikacin moderate
- Ethinyl Estradiol moderate
- Cholera Vaccine severe
- Furosemide moderate
- Cyclosporine moderate
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severe
The blood concentration of intravenous Zipenta Injection 500 mg 1 Vial may increase in the patients suffering from any kidney disease. Suitable dose adjustments are to be made based on the severity of the condition. Frequent monitoring of kidney function tests is necessary.
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moderate
Avoid if you experience severe diarrhea, abdominal pain, and blood in stools after taking Zipenta Injection 500 mg 1 Vial . Inform the doctor if you have any gastrointestinal diseases. Drink adequate amount of water to prevent dehydration.
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moderate
Use with caution if you have any seizure disorder or a family history of seizures. Appropriate dose adjustments are to be made if you have a kidney disease. Discontinue if seizure is due to Zipenta Injection 500 mg 1 Vial . Start with appropriate anticonvulsant medicine if it is clinically indicated.
General Instructions
Make sure that the medicine is dissolved properly. Do not take if any particulate matter is visible. Consult the doctor if you experience any undesirable effects. Do not stop taking before completion of course.
Other details
- Can be taken with or without food, as advised by your doctor
- To be taken as instructed by doctor
- May cause sleepiness
References
- practo.com - Ceftazidime [Internet]. Available from: https://www.practo.com/medicine-info/ceftazidime-50-api [cited 25 september 2019]. 16 Nov 2017
- medlineplus.gov - Ceftazidime [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a686007.html [cited 25 september 2019]. 11 September 2019
- dailymed.nlm.nih.gov - Ceftazidime [Internet]. Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=112c5457-8d71-49f5-b531-9761d7d38c93#s37 [cited 25 september 2019]. June 6, 2018
How to use Zipenta Injection 500 mg 1 Vial
IM: Inject deep IM into large mass muscle. IV: Ceftazidime can be administered IVP over 3-5 min or IV intermittent infusion over 15-30 min; final concentration for IV administration should not exceed 100 mg/ mL. Rotate IV sites every 72 hours. Assess for phlebitis and extravasation.
Reconstitution: IV: For IV bolus, reconstitute 1-2 gm with 10 mL SWFI, D5W, or NaCl. Shake to dissolve. For intermittent infusion, further dilute in 50-100 mL D5W or NS. IM: Reconstitute each gm with 3 mL SWFI or bacteriostatic water for injection.
Compatibility: D5NS, D5W, NS, SWFI.
Stability: For reconstituted solution and IV infusion in NS or D5W solution is stable for 24 hours at room temperature, 10 days when refrigerated, or 12 weeks when frozen.
what are the adverse effects of Zipenta Injection 500 mg 1 Vial?
Pain at inj site, hypersensitivity reactions. Gl disturbances, candidiasis, eosinophilia, neutropenia, leucopenia, thrombocytopenia, rise in liver enzymes and blood urea. Positive Coomb’s test, phlebitis or thrombophlebitis, thrombocytosis, pseudomembranous colitis, haemolytic anaemia.
What happens if I miss a dose of Zipenta Injection 500 mg 1 Vial?
Adults: 1-6 gm/day in 2 or 3 divided doses by IV or IM inj. Children: Above 2 mth, 30-100 mg/kg/day in 2 or 3 divided doses; under 2 mth, 25-60 mg/kg/day in 2 divided doses.
Bone Infection: IV: Adults: 2 gm every 12 hr. Children: 1 mth-12 yr: 30-50 mg/kg every 8 hr, up to 6 gm/day. 0-4 wk: 30 mg/kg every 12 hr.
Meningitis: IV: Adults: 2 gm every 8 hr. Children: 1 mth-12 yr: 30-50 mg/kg every 8 hr, up to 6 gm/day. 0-4 wk: 30 mg/kg every 12 hr.
Septicaemia: IV: Adults: 2 gm every 8 hr. Children: 1 mth-12 yr: 30-50 mg/kg every 8 hr, up to 6 gm/day. 0-4 wk: 30 mg/kg every 12 hr.
One of the following licensed pharmacy from the nearest location will deliver Zipenta Injection 500 mg 1 Vial. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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