
MBBS
Zoladex Depot Injection 3.6 mg 1’s
- Does this requires a prescription ? Yes
- Generic Name: Goserelin
- Manufactured by : ICI Pakistan Limited
- Drug Strength : 3.6 mg
- Drug Form : Depot Injection
- Pack Size : 1s
- Product SKU : pg_25263_35167
Zoladex Depot Injection contains Goserelin | belongs to GnRH analogue
How it works
Zoladex Depot Injection 3.6 mg 1’s works by decreasing the amount of certain hormones in the body.
Side effects
Major & minor side effects for Zoladex Depot Injection 3.6 mg 1’s
- Hypersensitivity severe
- Fast/irregular heart beat severe
- Trouble breathing severe
- Breast pain and tenderness severe
- Increase in blood glucose level severe
- Bone and joint pain severe
- Unusual sweating severe
- Unwanted hair growth severe
- Anxiety severe
Uses of Zoladex Depot Injection 3.6 mg 1’s
What is it prescribed for?
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Prostate cancer
This medicine is used in the treatment of advanced prostate cancer. It is also used along with radiation therapy for the treatment of localized prostate cancer.
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Endometriosis
This medicine is used in the treatment of endometriosis, a condition characterized by abnormal growth of uterine tissue, severe pain, and irregular menstrual cycles.
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Palliative treatment of breast cancer
This medicine is used in the palliative treatment of advanced breast cancer, to relieve symptoms of pain.
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Abnormal uterine bleeding
This medicine is used as an endometrial thinning agent prior to endometrial ablation for dysfunctional uterine bleeding.
Concerns
Frequently asked questions
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Onset of action
The amount of time required for this medicine to show its action is not clinically established.
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Duration of Effect
The amount of time for which this medicine remains active in the body is not clinically established.
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Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
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Is it habit forming?
No habit forming tendencies were reported.
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Usage in pregnancy?
This medicine is not recommended for use in pregnant women.
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Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women. Your doctor may prescribe a safer alternative based on your clinical condition.
When not to use?
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Allergy
This medicine is not recommended for use in patients with a known allergy to Zoladex Depot Injection 3.6 mg 1’s or any other components present along with it.
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Diabetes
This medicine may cause an increase in the blood glucose levels or may increase the chances of development of diabetes. It may also worsen the glycemic control of diabetic patients. Close monitoring of blood glucose levels is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
Dosage
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Missed Dose
If an appointment for a dose of Zoladex Depot Injection 3.6 mg 1’s is missed, contact your doctor immediately and schedule the dose as soon as possible.
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Overdose
Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
Interactions
Interaction with Medicines- Clozapine severe
- Amiodarone severe
- Dolasetron severe
- Ivabradine severe
- Efavirenz severe
General Instructions
This medicine injection is usually administered by a qualified healthcare professional. Follow all the instructions given by your doctor. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Other details
- Usage does not depend on food timings
- To be taken as instructed by doctor
- Does not cause sleepiness
References
- medlineplus.gov - Goserelin [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a601002.html [cited 7/9/2020]. 2020
How to use Zoladex Depot Injection 3.6 mg 1’s
Subcutaneous Implant: Insert the hypodermic needle into the subcutaneous fat. Do not try to aspirate with the goserelin syringe. If the needle is in a large vessel, blood will immediately appear in the syringe chamber. Change the direction of the needle so it parallels the abdominal wall. Push the needle in until the barrel hub touches the patient’s skin. Fully depress the plunger to discharge. Withdraw needle and bandage the site. Confirm discharge by ensuring tip of the plunger is visible within the tip of the needle.
Stability: The unit is sterile and comes in a sealed, light and moisture-proof, aluminum foil laminate pouch containing a dessicant capsule. Store at room temperature (do not exceed 25°C; 77°F).
UNLICENSED USE
Children: Gonadotrophin-dependent precocious puberty: Implant, by SC injection into anterior abdominal Wall. 3.6 mg every 28 days.
what are the adverse effects of Zoladex Depot Injection 3.6 mg 1’s?
Hot flushes, headaches, emotional lability, vaginal dryness, change in breast size tenderness, libido, rashes, hypercalcaemia, mood changes, depression, paraesthesia, abnormal BP, hyperhidrosis, inj site reactions, decreased bone density, wt gain, acne, alopecia, arthralgia, vulvovaginal dryness.
What happens if I miss a dose of Zoladex Depot Injection 3.6 mg 1’s?
Depot Inj 3.6 mg: Endometriosis: Adults: One 3.6 mg depot SC into anterior abdominal wall every 28 days for max 6 mth.
Prostatic cancer, advanced breast cancer in pre- and peri-menopausal women: Adults: One 3.6 mg depot SC into anterior abdominal wall every 28 days.
Pre-thinning of endometrium prior to endometrial ablation or resection: Adults: One 3.6 mg depot SC into anterior abdominal wall every 28 days for 4 or 8 wk.
Children: Not recommended.
LA Depot Inj 10.8 mg: Males: One 10.8 mg depot SC into the anterior abdominal wall, every 12 wk. Females & Children: Not recommended.
One of the following licensed pharmacy from the nearest location will deliver Zoladex Depot Injection 3.6 mg 1’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
Questions and Answers
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