Zygrel capsule 500 mg 3’s

 125.00

Manufactured by:
Active Pharmaceutical Ingredient:
Drug Strength: 500 mg
Drug Form : Capsule
Pack Size : 3s
Does this requires a prescription ?Yes

Zygrel capsule contains Azithromycin | belongs to Macrolide

SKU: pg_25411_35405 Categories: ,

Alternate brands

  • Zygrel capsule 500 mg 10’s
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  • Zrocin tablet 500 mg 6’s
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    How it works

    Zygrel capsule 500 mg 3’s medicine works by interfering with certain processes that help the bacteria to grow and increase in number.

    Side effects

    Major & minor side effects for Zygrel capsule 500 mg 3’s

    • Diarrhea severe
    • Abdominal pain severe
    • Difficult or painful urination severe
    • Vomiting severe
    • Fever severe
    • Acid or sour stomach
    • Aggression or anger
    • Excessive air or gas in stomach
    • Heartburn
    • Dry or scaly skin severe
    • Dizziness
    • Drowsiness

    Uses of Zygrel capsule 500 mg 3’s

    What is it prescribed for?

    • Community acquired pneumonia

      This medicine is used in the treatment of community-acquired pneumonia which is the most common type of lung infection caused by bacteria.

    • Ear Infection (Otitis Media)

      This medicine is used in the treatment of Otitis Media which is an infection of the middle ear with symptoms such as a headache, ear pain, ringing in the ears, loss of balance, etc.

    • Pharyngitis/Tonsilitis

      This medicine is used to treat a sore throat or Pharyngitis (an inflammation of the throat caused by bacteria or smoking). The most common symptoms of this condition include a cough, runny nose, difficulty in swallowing, fever with chills, etc.

    • Skin and soft tissue infections

      This medicine is used in the treatment of skin and soft tissue infections characterized by fever with chills, redness around hair follicles, yellowish rash, muscle pain, etc.

    • Cat Scratch Disease

      This medicine is used in the treatment of Cat Scratch Disease, which is an infection caused by the bacterium Bartonella henselae through the bite or scratch of a cat. It occurs within 1 to 2 weeks after the bite. This condition may be characterized by swollen lymph nodes near the site of the bite or scratch or most commonly on the neck.

    Concerns

    Frequently asked questions

    • Onset of action

      The effect of this medicine can be observed within 2 to 3 hours of administration of the dose.

    • Duration of Effect

      The effect of this medicine lasts for an average duration of 2 to 4 days.

    • Safe with Alchohol?

      Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

    • Is it habit forming?

      No habit-forming tendencies were reported.

    • Usage in pregnancy?

      This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

    • Usage while breast-feeding?

      This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any undesired side effects.

    When not to use?

    • This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any undesired side effects.

      This medicine is not recommended for use in patients with a known allergy to Zygrel capsule 500 mg 3’s, any other macrolides, or any other inactive ingredients present along with it.

    • Liver damage

      This medicine is not recommended for use in patients with a known history of cholestatic jaundice or hepatic impairment caused by prior use of this medicine.

    Warnings

    Warnings for special population
    • Pregnancy

      This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

    • Breast-feeding

      This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any undesired side effects.

    General Warnings
    • Myasthenia Gravis

      This medicine should be used with caution in patients with a history of myasthenia gravis due to the increased risk of worsening of the patient's condition. Any unusual symptoms should be reported to the doctor on priority. Replacement with a suitable alternative should be considered based on the clinical condition.

    • QT Prolongation

      This medicine should be used with caution in patients with a known history of arrhythmias, heart diseases, and patients who are on medicines that prolong QT intervals such as psychiatric drugs and anti-arrhythmic drugs due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative should be considered based on the clinical condition.

    • Diarrhea

      Antibiotic therapy will cause an imbalance in the normal microbial flora of the large intestine, which may promote the growth of a bacteria called Clostridium difficile and you may experience severe diarrhea as a result. Report any such incidence to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

    • Drug resistance

      Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

    • Driving or Operating machinery

      Use of this medicine may cause drowsiness or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

    Dosage

    • Missed Dose

      The missed dose should be administered as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.

    • Overdose

      All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

    Interactions

    Interaction with Medicines
    • Atorvastatin moderate
    • Amiodarone severe
    • Pimozide severe
    • Aluminium Hydroxide/Magnesium Hydroxide moderate
    • Digoxin moderate
    • Theophylline moderate
    Disease interactions
    • severe

      This medicine should be used with extreme caution in patients with a known history of arrhythmias, heart diseases, and patients who are on medicines that prolong QT intervals such as psychiatric drugs and anti-arrhythmic drugs. This medicine may further prolong QT intervals in such patients and worsen the patient's condition. Replacement with a suitable alternative should be considered based on the clinical condition.

    • moderate

      This medicine should be used with caution in patients with a known history of liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

    • moderate

      This medicine should be used with caution in patients with a known history of Myasthenia Gravis due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative should be considered based on the clinical condition.

    General Instructions

    Take/Administer this medicine with or without food. Do not consume/administer in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.

    Other details

    • Can be taken with or without food, as advised by your doctor
    • To be taken as instructed by doctor
    • May cause sleepiness

    References

    Additional Information>

    How to use Zygrel capsule 500 mg 3’s

    Administer over at least 60 min. Other medications should not be infused simultaneously through the same IV line.
    Reconstitution: Prepare initiation solution by adding 4.8 mL of SWFI to the 500 mg vial (resulting conc. 100 mg/mL). Use of a standard syringe is recommended due to the vacuum in the vial (which may draw additional solution through an automated syringe). The initial solution should be further diluted to a concentration of 1 mg/mL (500 mL) to 2 mg/mL (250 mL) in NS, D5W, LR.
    Compatibility: Stable in NS, D5W, LR.
    Y-site administration:
    Drug to Drug IV Compatibility: Diphenhydramine, ondansetron, pantoprazole.
    Drug to Drug IV Incompatibility: Amikacin, aztreonam, ceftriaxone, ciprofloxacin, famotidine, fentanyl, furosemide, gentamicin, imipenem, ketorolac, levofloxacin, morphine, piperacillin/tazobactam, tobramycin.
    Stability: Store intact vials of injection at room temperature. Reconstituted solution is stable for 24 hours when stored below 30°C (86°F). The diluted solution is stable for 24 hours at or below room temperature 30°C (86°F) and for 7 days if stored under refrigeration 5°C (41°F).

    what are the adverse effects of Zygrel capsule 500 mg 3’s?

    Gl upset, anorexia, allergy, rash, photosensitivity, arthralgia, oedema, angioneurotic oedema, anaphylaxis, abnormal liver function, hepatitis, cholestatic jaundice, dizziness, vertigo, convulsions, headache, somnolence, interstitial nephritis, acute renal failure, palpitations, arrhythmias, asthaenia, paraesthesia. Rarely hearing impairment, erythema multiforme. Stevens-Johnson syndrome, toxic epidermal necrolysis, hepatic necrosis, hepatic failure, neutropenia, taste disturbances, decreased blood bicarbonate, deafness, pruritus.

    What happens if I miss a dose of Zygrel capsule 500 mg 3’s?

    ORAL: Adults: 500 mg once daily for 3 days taken at least 1 hr before or 2 hr after food. Children: Under 3 yr (upto 15 kg), 10 mg/kg; 3-7 yr: 125 mg; 8-11 yr: 188 mg; 12-14 yr: 250 mg. All as a single daily dose for 3 days, taken at least 1 hr before or 2 hr after food.
    Upper Respiratory Tract Infections: Pharyngitis/Tonsillitis: Adults: 500 mg once daily for 1 day, then 250 mg once daily on day 2-5. Children: gt;2 yr: 12 mg/kg once daily for 5 day.
    Acute Bacterial Sinusitis: Adults: 500 mg once daily for 3 day or 2 gm single dose. Children: gt;6 mth: 10 mg/kg once daily for 3 day.
    Otitis Media: Children: gt;6 mth: 30 mg/kg as single dose; 10 mg/kg once daily for 3 day; or 10 mg/kg once daily for 1 day, then 5 mg/kg once daily for 2-5 days.
    Lower Respiratory Tract Infections: Adults: gt;16 yr: 500 mg once daily for one day, then 250 mg once daily for 2-5 days.
    COPD: Adults: 500 mg once daily for 3 days or 500 mg once daily for one day, then 250 mg once daily for 2-5 days.
    Mycobacterium Avium Complex: Adults: Prevention: 1200 mg once wk. Treatment: 600 mg once daily with ethambutol 15 mg/kg/day.
    Skin Infections: Adults: gt; 16 yr: 500 mg once daily for one day, then 250 mg once daily for 2-5 days.
    Genital infections: Adults: 1000 mg as a single dose.
    INJECTION: IV: Adults: Community-acquired pneumonia: 500 mg as a single dose for at least 2 days, followed by oral single daily dose of 500 mg for 7-10 days.
    Pelvic inflammatory disease: IV: Adults: Single dose of 500 mg for 1-2 days, followed by oral daily single dose of 250 mg for 7 days.

    One of the following licensed pharmacy from the nearest location will deliver Zygrel capsule 500 mg 3’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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