160.00

Content Details
Information on this page was last modified on : 2020/06/29 12:49:08 PM

Zymacef Injection 1 gm 1 Vial

Belongs to Category,

Zymacef Injection contains Cefotaxime | belongs to Cephalosporin

[display_substitute]

How it works

Zymacef Injection 1 gm 1 Vial medicine works by interfering with the bacterial cell wall synthesis and thus inhibits the growth of bacteria.

Side effects

Major & minor side effects for Zymacef Injection 1 gm 1 Vial

  • Abdominal pain severe
  • Black or tarry stools severe
  • Diarrhea severe
  • Dizziness severe
  • Increased heartbeat severe
  • Skin rash severe
  • Difficult or painful urination
  • Blurred vision severe
  • Fever with chills severe
  • Loss of appetite
  • Seizures severe
  • Pain at the injection site

Uses of Zymacef Injection 1 gm 1 Vial

What is it prescribed for?

  • Bacterial Septicemia

    This medicine is used in the treatment of Septicemia which is an infection of the blood caused by Staphylococci and Streptococcus pyogenes.

  • Gonococcal Infection

    This medicine is used in the treatment of Gonococcal infection which is a sexually transmitted bacterial infection caused by Neisseria gonorrhoeae.

  • Urinary Tract Infection

    This medicine is used in the treatment of infections in the urinary tract caused by E.coli, Pseudomonas aeruginosa, Enterococci and Klebsiella pneumoniae.

  • Pneumonia

    This medicine is used in the treatment of pneumonia, a common type of lung infection caused by Streptococcus pneumoniae or Haemophilus influenzae.

  • Osteomyelitis

    This medicine is used in the treatment of bone and joint infections like Osteomyelitis caused by Staphylococci and Streptococci species.

  • Surgical prophylaxis

    This medicine may be used preoperatively, during a procedure, or postoperatively to prevent infections associated with a surgical procedure.

  • Bacterial Meningitis

    This medicine is used to treat the inflammation of protective membranes of the brain and spinal cord (meningitis) caused by susceptible bacteria.

  • Intra-abdominal Infections

    This medicine is used in the treatment of intra-abdominal infections caused by susceptible bacteria.

  • Bone and Joint infections

    This medicine is used in the treatment of bone and joint infections caused by susceptible bacteria.

  • Skin and Soft tissue infections

    This medicine is used in the treatment of uncomplicated infections of the skin and skin structures caused by bacteria. These infections may include infected wounds, folliculitis, abscesses, cellulitis, ulcers, etc.

  • Gynecologic infections

    This medicine is used in the treatment of gynecologic Infections, including pelvic inflammatory disease, endometritis, pelvic cellulitis, and other infections of the female genital tract caused by susceptible bacteria.

Concerns

Frequently asked questions

  • Onset of action

    The effect of this medicine occurs rapidly after an intravenous or intramuscular administration. The amount of time required for the oral forms of this medicine to show their effect is not clinically established.

  • Duration of Effect

    The amount of time for which this medicine remains active in the body is not clinically established.

  • Safe with Alchohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    No habit forming tendency has been reported.

  • Usage in pregnancy?

    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking/receiving this medicine.

  • Usage while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

When not to use?

  • Allergy

    This medicine is not recommended for use in patients with a known allergy to Zymacef Injection 1 gm 1 Vial, any other Beta-lactam antibiotics, or any other inactive ingredients present along with it.

Warnings

Warnings for special population
  • Pregnancy

    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking/receiving this medicine.

  • Breast-feeding

    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Warnings

Warnings for special population
  • Drug-resistance

    Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

  • Sodium

    Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

  • Clostridium difficile-associated Diarrhea

    Avoid the use of this medicine if the patient experiences severe diarrhea after receiving therapy with this medicine. Antibiotic therapy will cause an imbalance in the normal microbial flora in the large intestine, which promotes the growth of a bacteria called Clostridium difficile. This will result in severe diarrhea. Appropriate corrective measures and replacement with a suitable alternative should be considered based on the clinical condition of the patient.

Dosage

  • Missed Dose

    Oral forms: If a dose of this medicine is missed, take the dose as soon as you remember it. If it is almost time for the next dose, skip the missed dose and take the next dose. Do not double the dose to make up for the missed one. Injection/ Infusion: Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of missing a dose is very low.

  • Overdose

    Oral forms: Seek emergency medical treatment or contact the doctor in case of an overdose. Injection/ Infusion: Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

Interactions

Interaction with Medicines
  • Amikacin moderate
  • Ethinyl Estradiol moderate
  • Cholera Vaccine severe
  • Furosemide moderate
Disease interactions
  • moderate

    This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis, since it may worsen the patient's condition. Report any incidence of severe diarrhea, abdominal pain, blood in stools, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

  • moderate

    This medicine should be used with extreme caution in patients with a history of seizure disorder or a family history of seizures due to the increased risk of recurrent seizures. Therapy should be discontinued if the patient experiences a seizure episode due to this medicine. Appropriate corrective measures and/or replacement with a suitable alternative may be necessary in some cases based on the clinical condition of the patient.

  • severe

    This medicine should be used with extreme caution in patients with a known history of renal diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

  • moderate

    This medicine should be used with caution in patients with liver diseases due to the increased risk of worsening of the patient's condition. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

General Instructions

Oral forms: Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor. Injection/ Infusion: This medicine should be administered only by a qualified healthcare professional in the clinical or hospital setting. Carefully follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report to the doctor all your current medicines as well as your medical conditions before receiving/taking this medicine. Report any undesired side effects to the doctor promptly.

Other details

  • Usage does not depend on food timings
  • To be taken as instructed by doctor
  • Does not cause sleepiness

References

How to use Zymacef Injection 1 gm 1 Vial

IM: Inject deep IM into large muscle mass. IV: Inject direct IV over 3-5 min. Infuse intermittent infusion over 30 min.
Reconstitution: IV: Reconstitute each 0.5, 1, or 2 gm vial with 10 mL of SWFI. Shake to dissolve. For intermittent IV infusion, further dilute in 50-100 mL of D5W or NS. IM: Reconstitute each 500 mg vial with 2 mL SWFI or bacteriostatic water for injection, each 1 gm vial with 3 mL diluent and each 2 gm vial with 5 mL diluent. Shake to dissolve.
Compatibility: D5 1/4 NS, D5 ½ NS, D5NS, D5W, D10W, LR, NS.
Stability: Reconstituted solution is stable for 12-34 hours at room temperature and 7-10 days when refrigerated and for 13 weeks when frozen. For IV infusion NS or D5W solution is stable for 24 hours at room temperature, 5 days when refrigerated.

what are the adverse effects of Zymacef Injection 1 gm 1 Vial

Pain at inj site, phlebitis, hypersensitivity reactions. GI upset, candidiasis, eosinophilia, neutropenia, leucopenia, granulocytopenia, agranulocytosis, thrombocytopenia, haemolytic anaemia, raised liver enzymes. Rarely, pseudomembranous colitis. Risk of encephalopathy and changes in renal function with high doses. Positive Coomb’s test.

What is the dose of Zymacef Injection 1 gm 1 Vial

Adults: 1 gm IV or IM every 12 hr; serious infections, 3-6 gm daily in three or four divided doses; max 12 gm daily. Use 2 gm by IV route. Children: Neonates, 50 mg/kg daily; others, 100-150 mg/kg daily. Both in two to four divided doses; max 200 mg/kg daily.
Bone Infection: IM/IV: Adults & Children: gt;50 kg: 1-2 gm every 8 hr. Max: 12 gm/day. Children: 1 mth-12 yr: lt;50 kg: 50-180 mg/kg/day divided into 4-6 doses. 1-4 wk: 50 mg/kg IV every 8 hr. 0-1 wk: 50 mg/kg IV every 12 hr.
Meningitis: IV: Adults & Children: gt;50 kg: 2 gm every 6-8 hr. Max: 12 gm/day. Children: 1 mth-12 yr: lt;50 kg: 50-180 mg/kg/day divided into 4-6 doses. 1-4 wk: 50 mg/kg IV every 8 hr. 0-1 wk: 50 mg/kg IV every 12 hr.
Septicaemia: IV: Adults & Children: gt;50 kg: 2 gm every 4 hr. Max: 12 gm/day. Children: 1 mth-12 yr: lt;50 kg: 50-180 mg/kg/day divided into 4-6 doses. 1-4 wk: 50 mg/kg IV every 8 hr. 0-1 wk: 50 mg/kg IV every 12 hr.

One of the following licensed pharmacy from the nearest location will deliver Zymacef Injection 1 gm 1 Vial. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts the your request based on valid prescription and availability.

Want to share this information?
Facebook
Twitter
LinkedIn
Something doesn't feel right ?

Reviews

There are no reviews yet.

Be the first to review “Zymacef Injection 1 gm 1 Vial”

Questions and answers of the customers

There are no questions yet. Be the first to ask a question about this product.

Only registered users are eligible to enter questions
Recent reviews
میڈیکل اسٹور مالکان کے لئے ھول سیل ریٹس پرفری ڈیلوری