Zyncillin Injection 500 mg 10 Vial

 230.00

Manufactured by:
Active Pharmaceutical Ingredient:
Drug Strength: 500 mg
Drug Form : Injection
Pack Size : 10 Vial
Does this requires a prescription ?Yes

Zyncillin Injection contains Ampicillin | belongs to Broad-spectrum penicillin

SKU: pg_25426_35425 Categories: ,

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    How it works

    Zyncillin Injection 500 mg 10 Vial works by preventing the creation of a component necessary for bacterial cell wall formation. Thus stops the growth and multiplication of the microorganism.

    Side effects

    Major & minor side effects for Zyncillin Injection 500 mg 10 Vial

    • Diarrhea severe
    • Skin rash severe
    • Fever with chills
    • Seizures
    • Fall in blood platelet levels
    • Fast/irregular heart beat
    • Abdominal pain rare
    • Abnormal liver function
    • Difficulty in breathing
    • Haemolytic anaemia rare
    • Mouth ulcers rare

    Uses of Zyncillin Injection 500 mg 10 Vial

    What is it prescribed for?

    • Respiratory Tract Infection

      Zyncillin Injection 500 mg 10 Vial is used in the treatment of respiratory tract infections like pneumonia and brochitis, caused by Streptococcus pneumoniae and Staphylococcus aureus.

    • Urinary Tract Infection

      Zyncillin Injection 500 mg 10 Vial is used in the treatment of infections of the urinary tract caused by E.coli, Pseudomonas aeruginosa, Enterococci and Klebsiella pneumoniae.

    • Intra abdominal infection

      This medicine is used in the treatment of Intraabdominal infections like gastroenteritis.

    • Shigellosis

      This medicine is used to treat shigellosis, a bacterial infectious disease caused by a group of bacteria called Shigella and which is characterized by fever, abdominal cramps, and diarrhea.

    • Typhoid fever

      This medicine is active against Salmonella typhi and used to treat typhoid fever.

    • Pneumonia

      This medicine is used for the treatment of community-acquired pneumonia which is the most common type of lung infection caused by bacteria such as Streptococcus pneumoniae, Haemophilus Influenzae, Moraxella catarrhalis, etc.

    • Ear Infection (Otitis Media)

      This medicine is used in the treatment of otitis media (middle ear infection) caused by bacteria such as Streptococcus pneumoniae, Haemophilus influenzae, staphylococci, Streptococcus pyogenes, etc.

    Concerns

    Frequently asked questions

    • Onset of action

      The peak effect of this medicine can be observed in 1 to 2 hours after an oral dose.

    • Duration of Effect

      The effect of this medicine lasts for an average duration of 3 to 6 hours.

    • Safe with Alchohol?

      Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

    • Is it habit forming?

      No habit forming tendencies have been reported.

    • Usage in pregnancy?

      This medicine is not known to cause any harm to the fetus. But the evidence is inadequate and it should be used only when necessary after consulting a doctor.

    • Usage while breast-feeding?

      This medicine is safe to use during breastfeeding. Any incidence of rashes on skin or diarrhea in the infant should be reported. It is advised to consult a doctor before taking this medicine.

    When not to use?

    • Allergy

      Zyncillin Injection 500 mg 10 Vial is not recommended if a patient is highly allergic to Zyncillin Injection 500 mg 10 Vial or other antibiotics of Penicillins and Cephalosporins groups.

    Warnings

    Warnings for special population
    • Pregnancy

      This medicine is not known to cause any harm to the fetus. But the evidence is inadequate and it should be used only when necessary after consulting a doctor.

    • Breast-feeding

      This medicine is safe to use during breastfeeding. Any incidence of rashes on skin or diarrhea in the infant should be reported. It is advised to consult a doctor before taking this medicine.

    General Warnings
    • Allergic Reaction

      Avoid if you have a known allergy to Zyncillin Injection 500 mg 10 Vial or Beta-lactam Antibiotics like penicillins and cephalosporins. Seek immediate medical attention if the patient experiences any allergic symptoms like rash, itching, nausea or vomiting, swelling of lips, hands, and feet.

    • Drug-resistance

      Usage of Zyncillin Injection 500 mg 10 Vial without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that is drug resistant.

    • Clostridium difficile-associated Diarrhea

      Do not take if you experience severe diarrhea after receiving Zyncillin Injection 500 mg 10 Vial. This is because the antibiotic therapy will cause an imbalance in the normal microbial flora in the large intestine, which promotes the growth of bacteria called clostridium difficile.

    • Mononucleosis

      Zyncillin Injection 500 mg 10 Vial is likely to cause rashes and bumps on the skin if the patient is suffering from Mononucleosis. Usage of Zyncillin Injection 500 mg 10 Vial is not recommended in such cases.

    Dosage

    • Missed Dose

      The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

    • Overdose

      Seek emergency medical treatment or contact the doctor in case of overdose.

    Interactions

    Interaction with Medicines
    • Atenolol moderate
    • Chloramphenicol moderate
    • Doxycycline moderate
    • Methotrexate severe
    • Warfarin moderate
    • Live cholera vaccine severe
    Disease interactions
    • severe

      This medicine should be used with caution in patients with a history of kidney diseases or active kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

    • moderate

      This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis, since it may worsen the patient's condition. Report any incidence of severe diarrhea, abdominal pain, blood in stools, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

    Food interactions
    • The absorption of Zyncillin Injection 500 mg 10 Vial may decrease in the presence of food. For proper absorption of the medicine, it should be taken at least 1 hour before or 2 hours after meals.

    General Instructions

    Take Zyncillin Injection 500 mg 10 Vial 1 hour before or 2 hours after meals. Do not take in larger amounts than advised. Consult the doctor if you experience any undesirable effects. Do not stop taking Zyncillin Injection 500 mg 10 Vial before completion of course.

    Other details

    • To be taken on an empty stomach
    • To be taken as instructed by doctor
    • May cause sleepiness

    References

    Additional Information>

    How to use Zyncillin Injection 500 mg 10 Vial

    May be administered by direct IV push over 3-5 min at a rate not to exceed 100 mg/min or IV intermittent infusion over 15-30 min at concentration not to exceed 30 mg/mL.
    Reconstitution: IM: Add (depending on manufacturer) 1.2 mL of SWFI or bacteriostatic water for injection to each 125 mg vial, 1 mL of diluent to each 250 mg vial, 1.8 mL of diluent to each 500 mg vial, 3.5 mL of diluent to each 1 gm vial, or 6.8 mL of diluents to each 2 gm vial. Intermittent infusion: Add 5 mL of SWFI or bacteriostatic water for injection to each 125, 250, or 500 mg vial or 7.4 to 10 mL of diluent to each 1 or 2 gm vial.
    Compatibility: Stable in D5W, NS. At Y-site administration, incompatible with amphotericin B cholesteryl sulphate complex, epinephrine, fluconazole, hydralazine, midazolam, ondansetron, sargramostim, verapamil, vinorelbine. In syringe, incompatible with erythromycin lactobionate, gentamicin, hydromorphone, kanamycin, lincomycin, metoclopramide. When admixed, incompatible with amikacin, chlorpromazine, dopamine, gentamicin, hydralazine, prochlorperazine.
    Stability: Solutions for IM or direct IV should be used within 1 hour. Solutions for IV infusion will be inactivated by dextrose at room temperature. If dextrose containing solutions are to be used, the resultant solution will only be stable for 2 hours versus 8 hours in NS. Stability of parenteral admixture in NS at room temperature (25°C) is 8 hours and at refrigeration (4°C) is 2 days.

    what are the adverse effects of Zyncillin Injection 500 mg 10 Vial?

    Hypersensitivity, GI upset, rash, transient rise in liver enzymes. Rarely pseudomembranous colitis.

    What happens if I miss a dose of Zyncillin Injection 500 mg 10 Vial?

    ORAL: Adults: 250 mg-1 gm every 6 hr. Children: 1 mth- 1 yr: 62.5 mg every 6 hr, the dose doubled in severe cases; 1-5 yr: 125 mg every 6 hr, the dose doubled in severe cases; 5-12 yr: 250 mg every 6 hr, the dose doubled in severe cases.
    Urinary Tract Infection: Adults & Children over 10 yr, 500 mg every 8 hr, Children: Under 10 yr, half the adult dose.
    Lower Respiratory Tract Infections: Adults & Children: gt; 20 kg: 250 mg every 6 hr. lt; 20 kg: 50 mg/kg/day divided as 6 hourly or 8 hourly dose.
    Upper Respiratory Tract Infections: Adults & Children: gt; 20 kg: 250 mg every 6 hr. lt; 20 kg: 50 mg/kg/day divided as 6 hourly or 8 hourly dose.
    INJECTION: Adults: 250-500 mg four to six times daily by IM or IV inj. Children: Half adult dose.
    Meningitis: IV: Adults & Children: 150-200 mg/kg/day given every 3-4 hr.
    Upper Respiratory Tract Infections: IM/IV: Adults & Children: gt; 40 kg: 250-500 mg every 8 hr. lt; 40 kg: 25-50 mg/kg every 6-8 hr.
    Endocarditis (in combination with other antibiotic if necessary): By IV infusion: Adults: 2 gm every 6 hr, increased to 2 gm every 4 hr e.g. in enterococcal endocarditis or if ampicillin used alone.

    One of the following licensed pharmacy from the nearest location will deliver Zyncillin Injection 500 mg 10 Vial. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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