Canaxit tablet contains Candesartan | belongs to Angiotensin II antagonist
Canaxit tablet 8 mg 2×7’s selectively blocks the binding of angiotensin II to AT1 in many tissues including vascular smooth muscle and the adrenal glands. This inhibits the AT1-mediated vasoconstrictive and aldosterone-secreting effects of angiotensin II and results in an overall decrease in blood pressure. This drug is greater than 10,000 times more selective for AT1 than AT2. Inhibition of aldosterone secretion may increase sodium and water excretion while decreasing potassium excretion.
Dizziness, headache, back pain, hyperkalaemia, hypotension, renal impairment.
Adults: Hypertension: Initial and usual maintenance dose; 8 mg once daily. Increase to 16 mg once daily if necessary. If BP control is inadequate after 4 wk treatment with 16 mg once daily, increase to max 32 mg once daily.
Treatment of patients with heart failure and impaired left ventricle systolic function: Initially 4 mg once daily. Double dose at minimum 2 wk intervals to max 32 mg once daily.
Children: Under 6 yr, not recommended. Hypertension: 6-18 yr, body-weight less than 50 kg, initially 4 mg once daily (lower dose in intravascular volume depletion), adjusted according to response, max 8 mg once daily; Body-weight 50 kg and over, initially 4 mg once daily (lower dose in intravascular volume depletion), adjusted according to response, max 16 mg once daily.
One of the following licensed pharmacy from the nearest location will deliver Canaxit tablet 8 mg 2×7’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts the your request based on valid prescription and availability.