Chloramphenicol capsule 250 mg 1000’s

 588.23

Manufactured by:
Active Pharmaceutical Ingredient:
Drug Strength: 250 mg
Drug Form : Capsule
Pack Size : 1000s
Does this requires a prescription ?Yes

Chloramphenicol capsule contains Chloramphenicol Inj/Oral | belongs to Chloramphenicol

SKU: pg_4286_6048 Category:

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    How it works

    This medicine works by preventing the growth and multiplication of the microorganisms. It interferes with certain vital processes in the cell and causes the lysis of the organism.

    Side effects

    Major & minor side effects for Chloramphenicol capsule 250 mg 1000’s

    • Gray syndrome in babies
    • Anemia
    • Dark colored urine
    • Sore throat and fever severe
    • Unusual bleeding or bruising severe
    • Confusion and delirium severe
    • Partial/total loss of vision severe
    • Difficulty in breathing severe
    • Headache
    • Nausea and Vomiting
    • Burning, numbness, tingling in the arms and feet
    • Swelling of face, lips, eyelids, tongue, hands and feet severe
    • Depression

    Uses of Chloramphenicol capsule 250 mg 1000’s

    What is it prescribed for?

    • Serious bacterial infections

      This medicine is used to treat infections caused by gram negative strains of bacteria which are severe and untreatable by other available medicines. Some of these infections are Bacterial meningitis, rickettsia, and others caused by susceptible organisms.

    • Infections of the eyes and ears

      This medicine is also sometimes used to treat severe bacterial infections of the eyes and ears.

    Concerns

    Frequently asked questions

    • Onset of action

      The time taken for this medicine to show it's effect varies depending on the intended use.

    • Duration of Effect

      The time duration for which this medicine remains effective is subject to vary depending on the intended use and dosing regimen.

    • Safe with Alchohol?

      Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Usage in pregnancy?

      This medicine is recommended for use in pregnant women only when absolutely necessary and the benefits outweigh the risk associated with use. Use of this medicine in the late part of the third trimester is not recommended.

    • Usage while breast-feeding?

      This medicine is recommended for use in pregnant women only when absolutely necessary and the benefits outweigh the risk associated with use. Use of this medicine in the late part of the third trimester is not recommended.

    When not to use?

    • Allergy

      This medicine is not recommended for use if you have a known history of allergy to Chloramphenicol capsule 250 mg 1000’s or any other component present with it.

    • Minor infections

      This medicine is not recommended for preventing or treating minor infections, especially the injectable forms.

    • Porphyria

      This medicine is not recommended for use in patients having this genetic disorder of the blood.

    • Bone marrow suppression

      This medicine is not recommended for use in patients with bone marrow suppression due to a disease or consumption of certain medicines.

    Warnings

    Warnings for special population
    • Pregnancy

      This medicine is recommended for use in pregnant women only when absolutely necessary and the benefits outweigh the risk associated with use. Use of this medicine in the late part of the third trimester is not recommended.

    • Breast-feeding

      Use of this medicine by breastfeeding women is not recommended unless absolutely necessary. The infant should be constantly monitored for side effects. Your doctor may ask you to discontinue breastfeeding while starting the treatment with this medicine.

    General Warnings
    • Liver and kidney impairment

      This medicine should be used with caution in patients suffering from an impairment of the liver and/or the kidney. The dosing should be as small as possible and the patient should be frequently monitored.

    • Vaccination

      Report the use of this medicine to the doctor if a vaccination is scheduled. This medicine can make the vaccination (taken to prevent bacterial diseases) ineffective and cause other complications as well.

    • Minor infections

      This medicine should not be used to treat minor infections or infections where the causative organism is not identified.

    • Drug resistance

      It is recommended to complete the full course of treatment even when symptoms improve. Failure to do so will result in the development of drug-resistant organisms and future treatment with the same medicine may become very difficult.

    • Long term use

      Long term and repeated use of this medicine should be avoided as the risk of getting a secondary infection are very high in such cases.

    • Gray syndrome

      This medicine can cause symptoms like abdominal swelling, pale or blue skin, shock, breathing difficulties, low temperature etc when given to a newborn or an infant. Use of this medicine should stop at the earliest to avoid fatalities.

    • Blood cell count

      Use of this medicine can lower the count of blood cells and cause anemia, bleeding, infections etc. Any sign and symptom that is indicative of a decreased blood cell count should be reported to the doctor immediately.

    • Diabetes

      This medicine should be administered with caution in diabetic patients with frequent monitoring of blood sugar levels.

    • Contraception failure

      This medicine can reduce the effect of hormonal contraceptives and hence the risk of unintended pregnancies are high. Alternate means of contraception should also be used while taking this medicine.

    • Pediatric use

      This medicine should be used with extreme caution in children, especially in infants. Constant monitoring is advised while administering this medicine.

    Dosage

    • Missed Dose

      Contact your doctor immediately if you miss a scheduled dose of this medicine.

    • Overdose

      Contact your doctor immediately if an overdose with this medicine is suspected.

    Interactions

    Interaction with Medicines
    • Warfarin moderate
    • Ethinyl Estradiol moderate
    • Cefixime moderate
    • Hydrocodone severe
    • Iron and vitamin B12 moderate
    • Iron and vitamin B12 severe
    Disease interactions
    • severe

      Use of this medicine in patients having a suppressed bone marrow can lead to fatal adverse effects. It could lead to several diseases of the blood in such patients. This medicine should be administered with extreme caution in patients with bone marrow suppression.

    • severe

      This medicine should be used with extreme caution in patients having an impairment of liver or/and kidney function. Use should be avoided unless absolutely necessary.

    General Instructions

    Take Chloramphenicol capsule 250 mg 1000’s as instructed by the doctor. Taking this medicine for the entire prescribed course is a must. The usage instructions mentioned on the label or the package insert should be strictly followed.

    Other details

    • Can be taken with or without food, as advised by your doctor
    • To be taken as instructed by doctor
    • May cause sleepiness

    References

    Additional Information>

    How to use Chloramphenicol capsule 250 mg 1000’s

    IV: Infuse via direct IV over 3-5 min; intermittent infusion over 30-60 min. IM: Do not administer IM.
    Compatibility: Stable in dextran 6% in dextrose, dextran 6% in NS, D5LR, D5¼NS, D5½NS, D5NS, D5W, D10W, fat emulsion 10%, LR, ½NS, NS. At Y-site administration incompatible with fluconazole. In syringe, incompatible with glycopyrrolate, metoclopramide. When admixed, incompatible with chlorpromazine, hydroxyzine, phenytoin, polymyxin B sulphate, prochlorperazine edisylate, prochlorperazine mesylate, promethazine, vancomycin.
    Stability: Store at room temperature prior to reconstitution, reconstituted solutions remain stable for 30 days, use only clear solutions, frozen solutions remain stable for 6 months.

    what are the adverse effects of Chloramphenicol capsule 250 mg 1000’s?

    Blood disorders including reversible and irreversible aplastic anaemia (with reports of resulting leukaemia), peripheral neuritis, optic neuritis, erythema multiforme, nausea, vomiting, glossitis, stomatitis, diarrhoea, nocturnal haemoglobinuria reported; grey syndrome (abdominal distension, pallid cyanosis, circulatory collapse) may follow excessive doses in neonates with immature hepatic metabolism.

    What happens if I miss a dose of Chloramphenicol capsule 250 mg 1000’s?

    ORAL: Adults: 50 mg/kg daily in divided doses six hourly. Children: Under 2 wk, half adult dose; over 2 wk, same as adult.
    INJECTION: Septicaemia: IV: Adults & Children: 50-100 mg/kg/day given every 6 hr. Infants: 25 mg/kg/day given every 6 hr.

    One of the following licensed pharmacy from the nearest location will deliver Chloramphenicol capsule 250 mg 1000’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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