₨ 41.18
MBBS
Diazepam Injection 10 mg 25 Ampx2 mL
- Does this requires a prescription ? Yes
- Generic Name: Diazepam
- Manufactured by : S.J&G. Fazul Ellahie
- Drug Strength : 10 mg
- Drug Form : Injection
- Pack Size : 25 Ampx2 mL
- Product SKU : pg_6330_8788
Diazepam Injection contains Diazepam | belongs to Benzodiazepine
Alternate brands of Diazepam Injection 10 mg 25 Ampx2 mL
| Brand Name | Price | Savings |
|---|---|---|
| Xepam tablet 5 mg 1000’s | ₨ 552.00 | You will pay -510.82 more |
| Xepam tablet 5 mg 30’s | ₨ 26.00 | You can save 15.18 |
| Xepam tablet 2 mg 30’s | ₨ 15.00 | You can save 26.18 |
| Xepam Soln 5 mg 30 mL | ₨ 23.00 | You can save 18.18 |
| Xepam Soln 5 mg 120 mL | ₨ 74.00 | You will pay -32.82 more |
How it works
It works by binding to certain chemicals in the brain and helps in relieving the symptoms.
Uses of Diazepam Injection 10 mg 25 Ampx2 mL
What is it prescribed for?
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Anxiety
Diazepam Injection 10 mg 25 Ampx2 mL is used in the treatment of anxiety disorders. Uneasiness, difficulty in sleeping, sweating of hands and feet are some of the symptoms of anxiety disorder.
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Alcohol withdrawal
Diazepam Injection 10 mg 25 Ampx2 mL is used in the treatment of symptoms of alcohol withdrawal like hallucinations, anxiety, and seizures.
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Muscle spasm
Diazepam Injection 10 mg 25 Ampx2 mL is used to relieve skeletal muscle spasm which occurs due to an inflammation of the muscle or joints.
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Adjunct prior to endoscopic procedures
Diazepam Injection 10 mg 25 Ampx2 mL is used in to relieve the symptoms of anxiety or stress in the patients undergoing endoscopic procedures.
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Preoperative sedation
Diazepam Injection 10 mg 25 Ampx2 mL is used to relieve the symptoms of anxiety and tension in the patients undergoing surgical procedures.
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Seizure disorder
Diazepam Injection 10 mg 25 Ampx2 mL is used in the treatment of seizure disorders.
Concerns
Frequently asked questions
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Onset of action
The peak effect of this medicine can be observed in 30 to 90 minutes for an oral dose.
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Duration of Effect
The effect of this medicine lasts for an average duration of 3 to 4 days.
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Safe with Alchohol?
Consumption of alcohol with this medicine is not recommended as it increases the risk of side effects like dizziness, difficulty in concentration. Do not perform activities that require mental alertness like driving or operating machinery.
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Is it habit forming?
Habit forming tendency has been reported
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Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless absolutely necessary. Discuss all the risks and benefits with your doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
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Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Discuss all the risks and benefits with your doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding for some period of time, based on the use of Diazepam Injection 10 mg 25 Ampx2 mL . Alternatively, your doctor may prescribe a safer alternative based on your clinical condition.
When not to use?
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Allergy
This medicine is not recommended for use in patients with a known allergy to Diazepam Injection 10 mg 25 Ampx2 mL .
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Myasthenia gravis
This medicine is not recommended for use in patients with myasthenia gravis due to the increased risk of serious adverse effects.
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Narrow-angle glaucoma
This medicine is not recommended for use in patients with narrow-angle glaucoma since it may worsen the patient's condition.
Warnings
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Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. Discuss all the risks and benefits with your doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
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Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Discuss all the risks and benefits with your doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding for some period of time, based on the use of Diazepam Injection 10 mg 25 Ampx2 mL . Alternatively, your doctor may prescribe a safer alternative based on your clinical condition.
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Suicidal thoughts
Use of benzodiazepines in depression conditions may increase the risk of suicide. Therefore this medicine should be used with caution and prescription size should be limited in patients with depression or suicidal tendencies.
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Withdrawal symptoms
Diazepam Injection 10 mg 25 Ampx2 mL should not be stopped immediately without informing the doctor due to the risk of withdrawal symptoms like convulsions, behavioral disorder, tremor, and anxiety. Gradual dose reduction should be made based on the outcomes in the patient.
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Myasthenis gravis
Diazepam Injection 10 mg 25 Ampx2 mL should be used with caution in patients with myasthenia gravis due to the increase in the risk of muscle weakness.
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Impaired liver function
Diazepam Injection 10 mg 25 Ampx2 mL should be used with caution in the patients with mild to moderate liver injury. Lowest possible doses should be initiated and increase the dose based on the patient's response. This medicine is not recommended in patients with severe liver impairment.
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Drowsiness
This medicine may cause drowsiness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any drowsiness during treatment with this medicine.
Dosage
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Missed Dose
Oral and Rectal forms: If you miss a dose of Diazepam Injection 10 mg 25 Ampx2 mL take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one. Injection: Since this medicine is administered by a qualified healthcare professional, the likelihood of missing a dose is very low.
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Overdose
Oral and Rectal forms: Seek emergency medical treatment or contact the doctor in case of an overdose. Injection: Since this medicine is administered by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated if an overdose is suspected.
Interactions
Interaction with Medicines- Cetirizine moderate
- Metoclopramide moderate
- Opoids severe
- Azole antifungal agents moderate
- Antihypertensives moderate
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Consumption of grapefruit juice is not recommended during treatment with this medicine due to the increased risk of adverse effects such as difficulty in breathing, sleepiness, fatigue, weakness, muscle pain, drowsiness, etc.
General Instructions
Take Diazepam Injection 10 mg 25 Ampx2 mL with or without food. Do not take in larger amounts than advised. Consult the doctor if you experience any undesirable side effects. Do not stop the use of this medicine without consulting your doctor.
References
- practo.com - Diazepam [Internet]. Available from: https://www.practo.com/medicine-info/diazepam-84-api [cited 18 september 2019]. 20 august 2018
- medlineplus.gov - Diazepam [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a682047.html [cited 18 september 2019]. 11 September 2019
- dailymed.nlm.nih.gov - Diazepam [Internet]. Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fa352464-14c8-49e9-b8b7-5a968b1cfa93 [cited 18 september 2019]. 22 march 2017
How to use Diazepam Injection 10 mg 25 Ampx2 mL
IV: Continuous infusion is not recommended because of precipitation in IV fluids and absorption of drug into infusion bags and tubing. In children, do not exceed 1-2 mg/min IVP; in adults 5 mg/min. By IV injection, 10 mg at a rate of 1 mL (5 mg) per min, repeated once after 10 min if necessary. Children under 12 years, 300-400 mcg/kg (maximum 10 mg). IM: Administration by this route is painful and absorption is slow and erratic. This route should be avoided where possible. If the IM route is used, inject undiluted.
Reconstitution: Most stable at pH 4-8, hydrolysis occurs at pH lt;3.
Compatibility: Do not mix IV product with other medications.
Y-site administration:
Drug to Drug IV Incompatibility: Amphotericin B cholesteryl sulphate complex, atracurium, cefepime. Diltiazem, fluconazole, gatifloxacin, heparin, heparin with hydrocortisone sodium succinate, hydromorphone, potassium chloride. Propofol, vecuronium, Vit B complex with C, meropenem, pancuronium, linezolid.
Stability: Stable at room temperature. Potency is retained up to 3 months. Protect from light.
what are the adverse effects of Diazepam Injection 10 mg 25 Ampx2 mL?
Drowsiness and light headedness, which may continue into the following day. Muscle weakness, ataxia, confusion, vertigo, GI upset, hypotension, visual disturbance, rash, impaired alertness and dexterity, headache, urinary retention, changes in libido, Rarely blood disorder, jaundice, respiratory depression, abnormal psychological reactions. Paradoxical reactions, anterograde amnesia. Dependence. Injection: rarely, thrombophlebitis.
What happens if I miss a dose of Diazepam Injection 10 mg 25 Ampx2 mL?
Adults: ORAL: Anxiety, insomnia, night terrors and somnambulism: 1-5 mg daily; others, 6-30 mg daily.
Muscle spasm, cerebral spasticity: Adults, Elderly, 1-30 mg daily; others, 2-60 mg daily. Both in divided doses.
Sedative cover in medical and surgical procedures: Usually 0.2 mg/kg.
Adults: INJECTION: Status epilepticus. Febrile convulsions: 10-20 mg by IV or IM inj repeated after 30-60 min if necessary. If indicated up to 3 mg/kg by IV infusion over 24 hr.
Adults: SUPPOSITORIES: Anxiety: 10-30 mg (higher dose divided); dose form not appropriate for less than 10 mg. Anxiety, insomnia, night terrors and somnambulism: Elderly, 5 mg; others, 10 mg. Both by IM or IV inj four hourly.
Muscle spasm, cerebral spasticity: Elderly, 5 mg; others, 10 mg. Both four hourly IM or IV.
Children: Status epilepticus, febrile convulsions, convulsions caused by poisoning: INJECTION: The following dose given by IV injection over 3-5 minutes, to be repeated once after 10 minutes if necessary. Neonate, 300-400 mcg/kg; 1 mth-12 yr, 300-400 mcg/kg (max 10 mg); 12-18 yr, 10 mg. By rectum (as rectal solution): The following dose to be repeated once after 10 minutes if necessary: 1 yr -2 yr, 5 mg; 2-12 yr, 5-10 mg; 12-18 yr, 10-20 mg.
Life-threatening acute drug-induced dystonic reactions: INJECTION: By IV injection over 3-5 minutes: 1 mth-12 yr, 100 mcg/kg repeat doses as necessary; 12-18 yr, 5-10mg repeat doses as necessary.
Muscle spasm in cerebral spasticity or in postoperative skeletal muscle spasm: ORAL: 1-12 mth, initially 250 mcg/kg twice daily; 1-5 yr, initially 2.5 mg twice daily; 5-12 yr, initially 5 mg twice daily; 12-18 yr, initially 10 mg twice daily, max total daily dose 40 mg.
Tetanus: INJECTION: IV: 1 mth-18 yr, 100-300 mcg/kg repeated every 1-4 hr. IV infusion (or by nasoduodenal tube): 1 mth-18 yr, 3-10 mg/kg over 24 hr, adjusted according to response.
One of the following licensed pharmacy from the nearest location will deliver Diazepam Injection 10 mg 25 Ampx2 mL. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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