ENDOCIN 25mg Capsule 500s

Frequently asked questions

• Onset of action

  The effect of this medicine can be observed in 30 minutes.

• Duration of Effect

  The effect of this medicine lasts for an average duration of 4 to 6 hours.

• Safe with Alchohol?

  This medicine should not be consumed with alcohol. Symptoms of stomach bleeding (such as the presence of dried and coffee colored blood in cough or stools) should be reported to the doctor immediately.

• Is it habit forming?

  No habit forming tendency have been reported.

• Usage in pregnancy?

  This medicine is not recommended for pregnant women.

• Usage while breast-feeding?

  This medicine is not recommended in breastfeeding women.

• Allergy

  Not recommended in patients with known allergy to ENDOCIN 25mg Capsule 500s or non-steroidal anti-inflammatory (NSAID) drugs

• Asthma

  Not recommended in patients with the history of NSAID-induced asthma, rhinitis, and urticaria.

• Coronary Artery Bypass Surgery (CABG)

  Not recommended in patients with recent heart surgery.

• Gastro-intestinal bleeding

  Not recommended in patients with peptic ulcer disease or any gastrointestinal bleeding disorders.

• Pregnancy

  This medicine is not recommended for pregnant women.

• Breast-feeding

  This medicine is not recommended in breastfeeding women.

• Gastro-intestinal bleeding

  This medicine may cause severe bleeding when taken for a long time. Elderly population with the history of the gastrointestinal disease are at higher risk. Any symptoms of blood in stools and vomiting should be informed to the doctor.

• Impaired kidney function

  This medicine is known to cause kidney injury. Close monitoring of kidney function is necessary. The dose should be adjusted based on the CrCl.

• Impaired liver function

  This medicine is known to cause liver injury. The baseline of liver enzymes should be obtained before starting the treatment. Inform the doctor if any signs of the increase in the liver enzymes appear.

• Effect on heart

  ENDOCIN 25mg Capsule 500s can have adverse effects on heart especially after a prolonged duration of use. It could increase the risk of diseases like stroke and heart attack which may be fatal.

ENDOCIN 25mg Capsule 500s should be taken following all labeled instructions. The duration and amount of medicine consumed should be as prescribed by the doctor. It can be taken with food or after food. Drink adequate amount of water to minimize the irritation caused in the stomach.

• drugs.com - Indomethacin [Internet]. Available from: https://www.drugs.com/mtm/indomethacin.html [cited 6/7/2020]. 2020
• wikipedia.org - Indomethacin [Internet]. Available from: https://en.wikipedia.org/wiki/Indometacin#:~:text=Mechanism%20of%20action,-Main%20article%3A%20Non&text=Indometacin%2C%20a%20non%2Dsteroidal%20anti,prostaglandin%20synthesis%20from%20arachidonic%20acid. [cited 6/7/2020].