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Information on this page was last modified on : 2020/06/26 4:19:45 PM

Koncept capsule 20 mg 14's

Koncept capsule contains Esomeprazole | belongs to Proton pump inhibitor

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How it works

This medicine works by interfering with the final step of acid release in the stomach. Thus, acidity in the stomach is decreased.

Side effects

Major & minor side effects for Koncept capsule 20 mg 14’s

  • Headache
  • Nausea
  • Flatulence
  • Stomach pain
  • Skin rash severe
  • Difficulty in breathing severe
  • Swelling of face, lips, eyelids, tongue, hands and feet severe
  • Irregular heartbeat severe
  • Severe diarrhea severe
  • Unusual tiredness and weakness
  • Fever
  • Decreased appetite

Uses of Koncept capsule 20 mg 14’s

What is it prescribed for?

  • Erosive Esophagitis

    Koncept capsule 20 mg 14’s is used in the treatment of severe ulcers caused by chronic acidity.

  • Gastroesophagal Reflux Disease

    Koncept capsule 20 mg 14’s is used in the treatment of a reflux disease where acid from the stomach and bile irritates the food pipe.

  • Helicobacter pylori Infection

    Koncept capsule 20 mg 14’s is used in combination with other medicines to treat Helicobacter Pylori infection.

  • Zollinger-Ellison Syndrome

    Koncept capsule 20 mg 14’s is used to treat a condition where excessive amount of acid is produced in the stomach due to tumors in the small intestine.

  • Other forms of Ulcers

    Koncept capsule 20 mg 14’s is also used to treat ulcers in the stomach (Gastric) and small intestines (Duodenal). It is also used to prevent ulcers caused due to stress and pain medications.

Concerns

Frequently asked questions

  • Onset of action

    The effect of this medicine can be observed within an hour of administration.

  • Duration of Effect

    The effect of this medicine lasts for an average duration of 16-18 hours.

  • Safe with Alchohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    No habit forming tendencies were reported.

  • Usage in pregnancy?

    This medicine can be used by pregnant women only when necessary and the potential benefits outweigh the risks involved. Consult your doctor before taking this medicine.

  • Usage while breast-feeding?

    This medicine is not recommended for use by breastfeeding women as it may cause some harm to the infant. However, if it is absolutely necessary to use this medicine, then breastfeeding should be discontinued. Consult your doctor before taking this medicine.

When not to use?

  • Allergy

    This medicine is not recommended for patients who are allergic to Koncept capsule 20 mg 14’s or any other drug of the same group i.e Benzimidazoles.

Warnings

Warnings for special population
  • Pregnancy

    This medicine can be used by pregnant women only when necessary and the potential benefits outweigh the risks involved. Consult your doctor before taking this medicine.

  • Breast-feeding

    This medicine is not recommended for use by breastfeeding women as it may cause some harm to the infant. However, if it is absolutely necessary to use this medicine, then breastfeeding should be discontinued. Consult your doctor before taking this medicine.

Warnings

Warnings for special population
  • Diarrhea

    This medicine has been associated with an increased incidence of Clostridium difficile associated diarrhea in some patients. Consult your doctor if you experience diarrhea that does not improve over time.

  • Liver disease

    Report any incidence of liver disease to the doctor. This medicine is not recommended for use if the impairment is severe. For mild to moderate impairment, this medicine can be given with suitable dose adjustment and safety monitoring.

  • Immune system disorder

    Use of this medicine for durations longer than medically recommended can cause skin disorders by affecting the immune system. Report any incidence of skin lesion formation to the doctor while using this medicine.

  • Risk of infections

    Use of this medicine increases the susceptibility to infections from bacteria.

  • Bone fracture

    Use of high dose of Koncept capsule 20 mg 14’s for prolonged duration may increase the risk of bone fractures especially in older patients and women. Supplements like Calcium citrate and Vitamin D should be taken after consulting the doctor.

  • Vitamin B12 deficiency

    Long-term treatment with Koncept capsule 20 mg 14’s may decrease the absorption of Vitamin B-12 in the body. Supplements can be taken after consulting the doctor.

Dosage

  • Missed Dose

    Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose then the missed dose should be skipped.

  • Overdose

    Contact your doctor immediately if an overdose is suspected. Symptoms may include confusion, drowsiness, blurred vision, dry mouth, and headache.

Interactions

Interaction with Medicines
  • Clopidogrel severe
  • Ketoconazole moderate
  • Methotrexate severe
  • Warfarin moderate
  • Nelfinavir severe
Disease interactions
  • moderate

    Report any incidence of liver disease to the doctor. Suitable adjustment in dosage might be needed based on the extent of the liver impairment

  • moderate

    Suitable adjustment in dosage and duration should be made for patients who are at risk for Osteoporosis related fracture. Established treatment guidelines should be strictly followed in such cases.

  • moderate

    Report any incidence of magnesium level imbalance in the body to the doctor. The imbalance could occur due to a disease or due to other medication used by the patient. Regular monitoring is recommended for patients taking Koncept capsule 20 mg 14’s in such cases.

Lab interactions

General Instructions

Take Koncept capsule 20 mg 14’s as instructed by the doctor. This medicine should be taken an hour before food. An adequate amount of water should be consumed with this medicine. Do not take this medicine for longer than the recommended duration.

Other details

  • Report the use of Koncept capsule 20 mg 14’s to the doctor before undergoing for the neuroendocrine/carcinoid tumor test. This medicine may give a false positive result for this diagnostic test.
  • To be taken as instructed by doctor
  • May cause sleepiness

References

How to use Koncept capsule 20 mg 14’s

Continuous or intermittent IV infusion in NaCl 0.9%:
Reconstitution: Reconstitute 40-80 mg with up to 100 mL infusion fluid; For intermittent infusion, give requisite dose over 10-30 min. For IV injection: Adults: Reconstitute powder with 5 mL NS. For IV infusion: Children: Initially reconstitute powder with 5 mL of NS, then further dilute to a final volume of 50 mL. Adults: Initially reconstitute powder with 5 mL of NS, LR, D5W, then further dilute to a final volume of 50 mL. Reconstituted solution in NS or LR should be used in 12 hours.
Stability: Store vials at 25°C; excursions permitted to 15°C-30°C. Protect from light. Reconstituted solution for infusion prepared in D5W should be used in 6 hours. Refrigeration is not required following reconstitution.

UNLICENSED USE
Children: ORAL: GERD in the presence of erosive reflux oesophagitis: 1-12 yr, body weight 10-20 kg, 10 mg once daily for 8 wk; body weight over 20 kg, 10-20 mg once daily for 8 wk; 12-18 yr, 40 mg once daily for 4 wk, continued for further 4 wk if not fully healed or symptoms persist; maintenance 20 mg daily.
GERD in the absence of erosive reflux oesophagitis: 1-12 yr, body weight over 10 kg, 10 mg once daily for 8 wk; 12-18 yr, 20 mg once daily for 4 wk.

what are the adverse effects of Koncept capsule 20 mg 14’s

Headache, GI upset, skin reaction, dry mouth. Rarely angioedema, anaphylaxis, fundic gland polyps.

What is the dose of Koncept capsule 20 mg 14’s

ORAL: Adults: Erosive oesophagitis: 40 mg once daily for 4-8 wk. Prevention of relapse, 20 mg once daily.
GERD without oesophagitis: 20 mg once daily for 4 wk. Maintenance, 20 mg once daily as required.
Triple therapy vs H. pylori: 20 mg twice daily with amoxicillin 1 gm twice daily and clarithromycin 500 mg twice daily for 7 days.
NSAID ulceration: 20 mg once daily for 4-8 wk, Prevention, 20 mg once daily.
Children: Not recommended.
INJECTION: Adults: Reflux oesophagitis: 40 mg once daily given as IV inj over a period of at least 3 min or as IV inf over a period of 10-30 min.
Symptomatic treatment of reflux oesophagitis: 20 mg once daily, half of the reconstituted solution be given as IV inj over a period of at least 3 min or as IV inf over a period of 10-30 min.
Healing of gastric ulcer associated with NSAID therapy & duodenal ulcers associated with NSAID therapy: 20 mg once daily. Treatment duration is usually short & transfer to oral as soon as possible.
Severe peptic ulcer bleeding (following endoscopic treatment: Initial IV infusion of 80 mg over 30 min, then by continuous IV infusion 8 mg/hr for 72 hr, then by mouth 40 mg once daily for 4 wk.
Children: By IV injection or by IV infusion. GERD in the presence of erosive reflux oesophagitis: 1-12 yr, body weight under 20 kg, 10 mg once daily; body weight over 20 kg, 10-20 mg once daily; 12-18 yr, 40 mg once daily.
GERD in the absence of erosive reflux oesophagitis: 1-12 yr, 10 mg once daily; 12-18 yr, 20 mg once daily.

One of the following licensed pharmacy from the nearest location will deliver Koncept capsule 20 mg 14’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts the your request based on valid prescription and availability.

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