₨ 4,000.00
MBBS
Mitoxantrona Injection 20 mg 1 Vial
- Does this requires a prescription ? Yes
- Generic Name: Mitoxantrone
- Manufactured by : Atco Laboratories Ltd
- Drug Strength : 20 mg
- Drug Form : Injection
- Pack Size : 1 vial
- Product SKU : pg_14943_20816
Mitoxantrona Injection contains Mitoxantrone | belongs to DNA-reactive cytotoxic
How it works
Mitoxantrona Injection 20 mg 1 Vial treats MS by stopping certain cells of the immune system from reaching the brain and spinal cord and causing damage.
Side effects
Major & minor side effects for Mitoxantrona Injection 20 mg 1 Vial
- Dizziness and fainting
- Irregular heartbeat
- Stomach pain
- Bloody and Cloudy urine
- Pale skin
- Yellow eyes or skin
- Shortness of breath
Uses of Mitoxantrona Injection 20 mg 1 Vial
What is it prescribed for?
-
Acute Non Lymphocytic Leukemia
This medicine is used in the treatment of a type of cancer of the blood and bone marrow which affects the red blood cells, platelets, and all white blood cells except lymphocytes.
-
Multiple sclerosis
This medicine is used to reduce the symptoms and slow rapidly evolving disability in patients with multiple sclerosis, a disease that damage the protective covering of nerves in the brain and spinal cord.
-
Prostate cancer
This medicine is used to relieve the pain related to prostate cancer.
Concerns
Frequently asked questions
-
Onset of action
The amount of time required for this medicine to show its action is not clinically established.
-
Duration of Effect
The amount of time for which this medicine remains active in the body is not clinically established.
-
Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
-
Is it habit forming?
No habit-forming tendencies were reported.
-
Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
-
Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.
When not to use?
-
Allergy
This medicine is not recommended for use in patients with a known allergy to Mitoxantrona Injection 20 mg 1 Vial or any other inactive ingredient present along with it.
Warnings
-
Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
-
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.
-
Bonemarrow suppression
This medicine should be used with caution in patients having conditions like thrombocytopenia, agranulocytosis, anemia, or bone marrow suppression due to the increased risk of worsening of the patient's condition. A complete blood count should be performed before initiating treatment with this medicine. Close monitoring of blood counts is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
-
Risk of infections
Use of this medicine may weaken the immune system and may make you more vulnerable to infections. It is advised that you avoid coming in contact with people suffering from an infection while receiving this medicine.
-
Driving or Operating machinery
Use of this medicine may cause dizziness, confusion, tiredness, etc. in some patients. Hence, it is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery if you experience any of these symptoms during treatment with this medicine.
-
Hyperuricemia
This medicine may elevate the blood uric acid levels in some patients. Close monitoring of blood uric acid levels is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
-
Liver impairment
This medicine should be used with extreme caution in patients suffering from liver diseases due to the increased risk of worsening of the patient's condition. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
Dosage
-
Missed Dose
Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low. If you miss any scheduled session, contact your doctor immediately for further instructions.
-
Overdose
Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
Interactions
Interaction with Medicines- Live attenuated vaccines and related products severe
- Etanercept severe
- Ganciclovir moderate
- Adalimumab severe
- Clozapine severe
-
severe
This medicine should be used with caution in patients having conditions like thrombocytopenia, agranulocytosis, anemia, or bone marrow suppression due to the increased risk of worsening of the patient's condition. A complete blood count should be performed before initiating treatment with this medicine. Close monitoring of blood counts is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
-
severe
This medicine should be used with caution in patients having a disease of the heart due to the increased risk of worsening of the patient's condition. Close monitoring of heart function is recommended for such patients. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.
-
severe
This medicine should be used with extreme caution in patients suffering from liver diseases due to the increased risk of worsening of the patient's condition. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
General Instructions
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Other details
- Usage does not depend on food timings
- To be taken as instructed by doctor
- May cause sleepiness
References
- medlineplus.gov - Mitoxantrone [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a608019.html [cited 9/9/2020]. 2020
How to use Mitoxantrona Injection 20 mg 1 Vial
Mitoxantrone HCl is administered by slow IV inf after dilution to at least 50 mL in D5W or NS. It is usually administered over 15 to 30 min through the tubing of a freely running IV solution or by continuous IV inf over 24 hours. It should not be given over less than three min.
Compatibility: Stable in D5NS, D5W, NS. Incompatible with amphotericin B cholesteryl sulphate complex, aztreonam, cefepime, doxorubicin liposome, paclitaxel, piperacillin/tazobactam, propofol.
Y-site administration: Incompatible with heparin when admixed.
Stability: Store intact vials at 15°C-25°C (59°F-77°F). Do not freeze. Opened vials may be stored under refrigeration for up to 7 days or at room temperature for 14 days. Solutions diluted for administration are stable for 7 days at room temperature or under refrigeration.
what are the adverse effects of Mitoxantrona Injection 20 mg 1 Vial?
Bone marrow depression, nausea, vomiting, alopecia, transient ECG alteration, acute arrhythmia, reduced left ventricular output, cardiac insufficiency, blue-green urine colouration.
What happens if I miss a dose of Mitoxantrona Injection 20 mg 1 Vial?
Adults: 12 mg/m² every 3 mth.
One of the following licensed pharmacy from the nearest location will deliver Mitoxantrona Injection 20 mg 1 Vial. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
Questions and Answers
There are no questions yet. Be the first to ask a question about this product.
Related products
Products listed on medicalstore.com.pk are 100% genuine and sourced from licensed pharmacies.
We work hard to bring you unimaginable discounts without compromising on quality.
We uses SSL (standard security technology) to ensure data privacy of all our customers.
Reviews
There are no reviews yet.