Oxaliplatin Infusion 150 mg 1 Vialx30 mL

 28,500.00

Manufactured by:
Active Pharmaceutical Ingredient:
Drug Strength: 150 mg
Drug Form : Infusion
Pack Size : 1 Vialx30 mL
Does this requires a prescription ?Yes

Oxaliplatin Infusion contains Oxaliplatin | belongs to Alkylating agent

SKU: pg_17504_24208 Categories: ,

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    How it works

    Oxaliplatin Infusion 150 mg 1 Vialx30 mL works by stopping the growth of cancer cells by inhibiting the DNA synthesis.

    Side effects

    Major & minor side effects for Oxaliplatin Infusion 150 mg 1 Vialx30 mL

    • Burning or tingling sensation of hands and feet severe
    • Cough severe
    • Fever and chills severe
    • Low WBC and Platelet count severe
    • Mouth ulcers severe
    • Loss of appetite severe
    • Skin rash severe
    • Nausea and Vomiting severe
    • Swelling of eyelids, face, lips severe
    • Acid or sour stomach
    • Sneezing
    • Stomach discomfort and pain
    • Running Nose
    • Change in taste
    • Hair loss

    Uses of Oxaliplatin Infusion 150 mg 1 Vialx30 mL

    What is it prescribed for?

    • Colorectal Cancer

      Oxaliplatin Infusion 150 mg 1 Vialx30 mL is used in the treatment of cancer that affects the large intestine of the digestive system.

    Concerns

    Frequently asked questions

    • Onset of action

      The peak effect of this medicine can be observed in 2 hours after intravenous injection.

    • Duration of Effect

      The peak effect of this medicine can be observed in 2 hours after intravenous injection.

    • Safe with Alchohol?

      Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Usage in pregnancy?

      This medicine is not recommended for pregnant women.

    • Usage while breast-feeding?

      This medicine is not recommended in breastfeeding women.

    When not to use?

    • Allergy

      Not recommended in patients with known allergy to Oxaliplatin Infusion 150 mg 1 Vialx30 mL or other platinum-containing compounds.

    • Severe myelosuppression

      Not recommended in patients with low white blood cell and platelet count.

    Warnings

    Warnings for special population
    • Pregnancy

      This medicine is not recommended for pregnant women.

    • Breast-feeding

      This medicine is not recommended in breastfeeding women.

    General Warnings
    • Impaired kidney function

      This medicine may cause severe kidney injury. The risk may increase if taken with aminoglycoside antibiotics. Close monitoring of serum creatinine, urea, and sodium levels is necessary.

    • Hearing impairment

      This medicine may cause the hearing problem which is more common in children. Audiometric testing should be performed before initiating the treatment and also before every dose. Any symptoms of the hearing problem should be reported to the doctor.

    • Allergy

      This medicine may cause serious skin reactions. Discontinue the treatment if any symptoms of allergy appear and do not restart.

    • Blood cell count

      This medicine may lower the white blood cells and platelets. Close monitoring of blood cell count is necessary. Do not start the treatment if the cell count is low.

    • Infections

      The chances of occurring infections are more in patients receiving this medicine. Hold the chemotherapy and start with the broad-spectrum antibiotics if there are any signs and symptoms of fever. Close monitoring of the body temperature and the blood cell count is necessary.

    • Lung toxicity

      This medicine may cause rare but fatal lung injury. Inform the doctor if you have any lung disease. Any symptoms of difficulty in breathing, non-productive cough should be reported to the doctor. Discontinue the treatment until the exact cause is identified.

    • Impaired liver function

      This medicine may cause liver injury. The baseline of liver enzymes should be obtained before initiating the therapy. Any signs of elevation in the liver enzymes should be informed to the doctor. Discontinue the treatment until the levels reach to normal.

    • Neuropathy

      This medicine may cause severe nerve damage which may develop within hours of adminstration and resolves within 14 days or may persist for more than 14 days. Any symptoms of tingling or burning sensation of hands and feet should be reported to the doctor.

    Dosage

    • Missed Dose

      It is advised not to miss any dose. If you missed any dose, you should contact your doctor immediately.

    • Overdose

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    Interactions

    Interaction with Medicines
    • Clozapine severe
    • Vancomycin moderate
    • Atorvastatin moderate
    • Live vaccines severe
    Disease interactions
    • severe

      This medicine should be used with caution in patients with heart diseases due to the increase in the risk of irregular heart rhythm. Monitor the potassium levels, which may exacerbate the condition. Any symptoms of heart palpitation should be reported to the doctor.

    • severe

      This medicine may cause rare but fatal lung injury. Inform the doctor if you have any lung disease. Any symptoms of difficulty in breathing, non-productive cough should be reported to the doctor. Discontinue the treatment until the exact cause is identified.

    General Instructions

    This medicine is given in multiple cycles. It is important to receive the every scheduled dose and make a note of next scheduled dose. Close monitoring of blood cells counts and kidney function.

    Other details

    • Usage does not depend on food timings
    • To be taken as instructed by doctor
    • May cause sleepiness

    References

    Additional Information>

    How to use Oxaliplatin Infusion 150 mg 1 Vialx30 mL

    For administration by IV inf, the liquid concentrated injection must be diluted in 250 to 500 mL of D5W. Chloride containing solutions must not be used for dilution.
    Compatibility: Incompatible with alkaline solutions (e.g. fluorouracil) and chloride-containing solutions. Flush infusion line with D5W prior to and following, administration of concomitant medications via same IV line.
    Stability: Store intact vials at room temperature of 25°C (77°F) and under normal lighting; excursions permitted to 15°C-30°C (59°F-86°F). Reconstituted solutions may be stored up to 24 hours at room under refrigeration at 2°C-8°C (36°F-46°F). Diluted solution is stable up to 6 hours at room temperature of 20°C-25°C (68°F-77°F) or up to 24 hours under refrigeration at 2°C-8°C (36°F-46°F).

    what are the adverse effects of Oxaliplatin Infusion 150 mg 1 Vialx30 mL?

    Peripheral sensory neuropathy, pharyngolaryngeal dysaesthesia, anaemia, neutropenia, thrombocytopenia, nausea, diarrhoea, mucositis/stomatitis, alopecia. Raised liver enzymes, allergic reactions, ototoxicity, renal function disturbance, transient loss of visual acuity.

    What happens if I miss a dose of Oxaliplatin Infusion 150 mg 1 Vialx30 mL?

    Adults: Metastatic colorectal cancer: 85 mg/m² every 2 wk by IV infusion over 2-6 hr prior to administration of 5-FU.
    Stage III colon cancer: 85 mg/m² every 2 wk for 12 cycles by IV infusion over 2-6 hr prior to administration of 5-FU.
    Children: Not recommended.

    One of the following licensed pharmacy from the nearest location will deliver Oxaliplatin Infusion 150 mg 1 Vialx30 mL. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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