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Information on this page was last modified on : 2021/05/08 3:41:05 PM

RANZOL 500mg Tablet SR 14s

Ranolazine:500mg | Antianginal drugs

Manufactured / Marketed By : Maple Product Form : Tablet SRPack Size : 14sIngredients : Ranolazine:500mgGeneric Category : Antianginal drugs

How it works

RANZOL 500mg Tablet SR 14s blocks late inward sodium currents in cardiomyocytes. In the ischemic myocardium, late inward sodium currents contribute to an elevation in intracellular sodium, which leads to an increase in intracellular calcium through the sodium-calcium exchanger.

Side effects

Major & minor side effects for RANZOL 500mg Tablet SR 14s

  • Dizziness severe
  • Ringing or buzzing in the ears severe
  • Chest tightness severe
  • Headache severe
  • Blurred vision severe
  • Constipation
  • Dry mouth
  • Stomach pain
  • Loss of strength rare

Uses of RANZOL 500mg Tablet SR 14s

What is it prescribed for?

  • Angina Pectoris

    This medicine is used for the treatment of chronic angina pectoris (severe chest pain) caused due to reduced flow of blood and oxygen to the heart. It is not recommended as first-line therapy for treating acute angina attacks.

Concerns

Frequently asked questions

  • Onset of action

    The amount of time required for this medicine to show its action is not clinically established.

  • Duration of Effect

    The amount of time for which this medicine remains active in the body is not clinically established.

  • Safe with Alchohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    No habit forming tendency has been reported.

  • Usage in pregnancy?

    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

  • Usage while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

When not to use?

  • Severe liver disease

    This medicine is contraindicated in patients suffering from kidney diseases due to the increased risk of severe adverse effects.

  • Drug interaction

    This medicine is not recommended for use in patients receiving strong CYP3A inhibitors like ketoconazole, clarithromycin, nelfinavir, and CYP3A inducers like carbamazepine, phenobarbital, phenytoin, rifampin, etc. due to the increased risk of worsening severe adverse effects.

  • Allergy

    This medicine is not recommended for use if you have a known history of allergy to RANZOL 500mg Tablet SR 14s or any other inactive ingredients present in the formulation.

Warnings

Warnings for special population
  • Pregnancy

    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

  • Breast-feeding

    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

General Warnings
  • Elderly population

    This medicine should be used with caution in patients more than 60 years of age due to an increase in the risk of undesired effects. Close monitoring of kidney function is necessary. The dose should be adjusted based on the kidney function.

  • Low body weight

    This medicine should be used with caution in patients less than 60 kg of body weight due to an increase in the risk of undesired effects. The dose should be adjusted based on body weight.

  • Use in children

    This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.

  • Driving or operating machinery

    This medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Dosage

  • Missed Dose

    The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already the time for your next scheduled dose.

  • Overdose

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

Interaction with Medicines
  • Metformin moderate
  • Phenytoin severe
  • Digoxin moderate
  • Atorvastatin severe
Disease interactions
  • severe

    This medicine should be used with extreme caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of the liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

  • moderate

    This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

  • moderate

    This medicine should be used with caution in patients with a history of prolonged QT interval and patients using medicines that prolong QT interval. Appropriate dose adjustments should be made under your doctor's supervision.

Food interactions
  • Consumption of grapefruit juice while taking this medicine is not recommended due to an increase in the risk of dizziness, fast heartbeat, and fainting. Any such symptoms should be reported to the doctor on priority.

General Instructions

Take this medicine as advised by the doctor. Do not consume larger quantities than prescribed. It is advised that you inform the doctor if you have a history of liver or kidney disease. Proper lifestyle modifications should be adopted along with the medicine to prevent further complications. Report to the doctor if you experience any undesired effects while receiving the medicine.

Other details

  • Can be taken with or without food, as advised by your doctor
  • To be taken as instructed by doctor
  • May cause sleepiness

References

Additional Information:

One of the following licensed pharmacy from the nearest location will deliver RANZOL 500mg Tablet SR 14s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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