₨ 330.00
MBBS
RAZIN ER 1gm Tablet 14s
- Does this requires a prescription ? Yes
- Generic Name: Ranolazine:1g
- Manufactured by : Getz Pharma (PVT) LTD.
- Drug Strength : 1g
- Drug Form : Tablet
- Pack Size : 14s
- Product SKU : dis_22267
Ranolazine:1g | Antianginal drugs
Manufactured / Marketed By : Getz Product Form : TabletPack Size : 14sIngredients : Ranolazine:1gGeneric Category : Antianginal drugs
How it works
RAZIN ER 1gm Tablet 14s blocks late inward sodium currents in cardiomyocytes. In the ischemic myocardium, late inward sodium currents contribute to an elevation in intracellular sodium, which leads to an increase in intracellular calcium through the sodium-calcium exchanger.
Side effects
Major & minor side effects for RAZIN ER 1gm Tablet 14s
- Dizziness severe
- Ringing or buzzing in the ears severe
- Chest tightness severe
- Headache severe
- Blurred vision severe
- Constipation
- Dry mouth
- Stomach pain
- Loss of strength rare
Uses of RAZIN ER 1gm Tablet 14s
What is it prescribed for?
-
Angina Pectoris
This medicine is used to relieve chest pain in patients with conditions like Angina pectoris.
Concerns
Frequently asked questions
-
Onset of action
The amount of time needed for this medicine to show its effect is not clinically established. However, it takes 2 to 6 hours to reach maximum concentration in the blood.
-
Duration of Effect
This medicine remains active in the body for an average duration of 21 hours after an oral dose.
-
Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
-
Is it habit forming?
No habit forming tendency has been reported.
-
Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
-
Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
When not to use?
-
Liver disease
This medicine is contraindicated in patients suffering from kidney diseases due to the increased risk of severe adverse effects.
-
Drug interaction
This medicine is not recommended for use in patients receiving strong CYP3A inhibitors like ketoconazole, clarithromycin, nelfinavir and CYP3A inducers like carbamazepine, phenobarbital, phenytoin, rifampin, etc. due to alteration in RAZIN ER 1gm Tablet 14s blood levels.
Warnings
-
Pregnancy
This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
-
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
-
Elderly population
This medicine should be used with caution in patients more than 60 years of age due to an increase in the risk of undesired effects. Close monitoring of kidney function is necessary. The dose should be adjusted based on the kidney function.
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Low body weight
This medicine should be used with caution in patients less than 60 kg of body weight due to an increase in the risk of undesired effects. The dose should be adjusted based on the body weight.
Dosage
-
Missed Dose
The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already the time for your next scheduled dose.
-
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
Interactions
Interaction with Medicines- Metformin moderate
- Phenytoin severe
- Digoxin moderate
- Atorvastatin severe
-
severe
This medicine is not recommended for use in patients with a history of liver disease or active liver disease due to an increase in the risk of serious adverse effects. An alternate treatment option should be considered based on the clinical condition.
-
moderate
This medicine should be used with caution in patients with a history of kidney disease or active kidney disease due to an increase in the risk of serious adverse effects. An alternate treatment option should be considered based on the clinical condition.
-
moderate
This medicine should be used with caution in patients with a history of prolonged QT interval and patients using medicines that prolong QT interval. Appropriate dose adjustments should be made under your doctor's supervision.
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Consumption of grapefruit juice while taking RAZIN ER 1gm Tablet 14s is not recommended due to an increase in the risk of dizziness, fast heartbeat, and fainting. Any such symptoms should be reported to the doctor on priority.
General Instructions
Take This medicine as advised by the doctor. Do not consume larger quantities than prescribed. It is advised that you inform the doctor if you have a history of liver or kidney disease. Proper lifestyle modifications should be adopted along with the medicine to prevent further complications. Report to the doctor if you experience any undesired effects while receiving the medicine.
Other details
- Can be taken with or without food, as advised by your doctor
- To be taken as instructed by doctor
- Does not cause sleepiness
References
- cvpharmacology - Ranolazine [Internet]. Available from: https://www.cvpharmacology.com/Angina/late%20sodium%20blocker#:~:text=Ranolazine%20represents%20a%20new%20class,through%20the%20sodium%2Dcalcium%20exchanger. [cited 2/9/2020].
- medlineplus - Ranolazine [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a606015.html [cited 2/9/2020]. 2020
One of the following licensed pharmacy from the nearest location will deliver RAZIN ER 1gm Tablet 14s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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