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Information on this page was last modified on : 2020/06/26 4:18:43 PM

Transmac capsule 250 mg 2x50's

Transmac capsule contains Tranexamic Acid, Inj/Oral | belongs to Antifibrinolytic

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How it works

This medicine works by preventing certain enzymes that break a blood clot formed in the body. Thus the breakdown of clot is either slowed down or completely stopped.

Side effects

Major & minor side effects for Transmac capsule 250 mg 2×50’s

  • Headache
  • Sinusitis like symptoms
  • Back pain
  • Diarrhea
  • Pale skin
  • Allergic Skin Reaction severe
  • Muscle or joint pain
  • Unusual tiredness and weakness
  • Change in color vision severe
  • Difficulty in breathing severe
  • Swelling of face, lips, eyelids, tongue, hands and feet severe
  • Pain in the chest region severe
  • Dizziness and fainting severe
  • Presence of blood in cough severe

Uses of Transmac capsule 250 mg 2×50’s

What is it prescribed for?

  • Menorrhagia

    Tranemic 500 MG Injection is used for the treatment of heavy bleeding that occurs during menstrual cycles.

  • Short-term management of hemorrhage

    Tranemic 500 MG Injection is used for short term management of internal bleeding in patients who have hemophilia.

  • Hereditary angioedema

    Tranemic 500 MG Injection is also sometimes used for the prevention of episodes of edema in patients suffering from this rare genetic disorder.

Concerns

Frequently asked questions

  • Onset of action

    The effect of this medicine can be observed within 10-30 minutes of intravenous administration. Time taken for the effect to show may increase with other dosage forms.

  • Duration of Effect

    The effect of this medicine lasts for an average duration of 2-4 hours.

  • Safe with Alchohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    No habit forming tendencies were reported.

  • Usage in pregnancy?

    Use of this medicine by pregnant women is not recommended unless absolutely necessary. The benefits of medication along with associated risks should be considered before using it. Consult your doctor before taking this medicine.

  • Usage while breast-feeding?

    This medicine can be used by women who are breastfeeding as the risk of adverse effects of nursing infants are less. Consult your doctor before taking this medicine.

When not to use?

  • Allergy

    This medicine is not recommended for use in patients who have a known history of allergy to Transmac capsule 250 mg 2×50’s or any other ingredient present in the dosage form.

  • Acquired defective color vision

    This medicine is not recommended for use in people having a defective color vision as it could make toxicity determination very difficult.

  • Subarachnoid hemorrhage

    This medicine is not recommended for use in people who have hemorrhage in the area between the brain and its outer covering.

  • Obstructive blood clotting disorder

    Obstructive blood clotting disorder

Warnings

Warnings for special population
  • Pregnancy

    Use of this medicine by pregnant women is not recommended unless absolutely necessary. The benefits of medication along with associated risks should be considered before using it. Consult your doctor before taking this medicine.

  • Breast-feeding

    This medicine can be used by women who are breastfeeding as the risk of adverse effects of nursing infants are less. Consult your doctor before taking this medicine.

Warnings

Warnings for special population
  • Use of hormonal contraceptives

    This medicine is not recommended for use in women who are using hormonal contraceptives (pills, patches, vaginal rings, or injections) as the risk of adverse effects are significantly high.

  • Clotting disorders

    This medicine is not recommended for use if you have a history of clotting disorders or have an active disorder. Patients who are exposed to risk factors and are likely to develop this disorders should not be given this medicine.

  • Eye disorders

    This medicine is not recommended for use if you have a history of any disease where the blood vessels of the eye are obstructed due to clot formation.

  • Other medicines

    This medicine is known to interact with a large number of other medicines that you might be using. Report the use of all medications including supplements and herbs to the doctor before receiving Transmac capsule 250 mg 2×50’s .

Dosage

  • Missed Dose

    Take the missed dose as soon as you remember given that the next scheduled dose is at least 6 hours away. If you missed a scheduled injection of this medicine, then contact your doctor for further instructions.

  • Overdose

    Contact a doctor immediately if an overdose with Transmac capsule 250 mg 2×50’s is suspected.

Interactions

Interaction with Medicines
  • Tamoxifen severe
  • Ethinyl Estradiol severe
  • Tretinoin severe
  • Factor IX complex severe
Disease interactions
  • moderate

    This medicine should be used with caution in people with an abnormal or impaired kidney function.

Food interactions
Lab interactions

General Instructions

Take Tranemic 500 MG Injection as prescribed by the doctor. Do not consume more or less than the prescribed quantity of this medicine. It is advised to follow all the usage related instructions mentioned on the label.

Other details

  • Can be taken with or without food, as advised by your doctor
  • To be taken as instructed by doctor
  • May cause sleepiness

References

How to use Transmac capsule 250 mg 2×50’s

IV injection or administer as IV continuous infusion, 25-50 mg/kg over 24 hours. Can be mixed with solutions for infusion such as NS or D5W.
Stability: Store at 15°C-30°C (59°F-86°F).

UNLICENSED USE
Children: Injection/Infusion not recommended for children under 1 yr. Not recommended for reduction of blood loss during cardiac surgery.
Inhibition of fibrinolysis, hereditary angioedema: ORAL: 1 mth-1 yr, 15-25 mg/kg (max 1.5 gm) 2-3 times daily. INJECTION: By IV injection over at least 10 minutes, 1 mth-1 yr, 10 mg/kg (max 1 gm) 2-3 times daily. By continuous IV infusion, 1 mth-1 yr, 45 mg/kg over 24 hr.
Menorrhagia: ORAL: 12-18 yr, 1 gm 3 times daily for up to 4 days, max 4 gm daily (initiate when menstruation has started).

what are the adverse effects of Transmac capsule 250 mg 2×50’s

Gastrointestinal disorders, nausea, vomiting, diarrhoea, hypotension, convulsions, rarely thromboembolic events, colour vision disturbances (discontinue); giddiness on rapid IV injection.

What is the dose of Transmac capsule 250 mg 2×50’s

Adults: ORAL: Local fibrinolysis: 15-25 mg/kg body weight two-three times daily.
Menorrhagia: Initiated when heavy bleeding started, 1-1.5 gm 3-4 times daily for 3-4 days.
Hereditary angioedema: 1-1.5 gm 2-3 times daily.
INJECTION: Local fibrinolysis: 0.5-1 gm by slow IV 3 times daily.
General fibrinolysis: 1 gm (or 15 mg/kg) every 6-8 hr.
Children: Injection/Infusion not recommended for children under 1 yr. Not recommended for reduction of blood loss during cardiac surgery. Inhibition of fibrinolysis, hereditary angioedema: ORAL: 1 mth-18 yr, 15-25 mg/kg (max 1.5 gm) 2-3 times daily. INJECTION: By IV injection over at least 10 minutes, 1-18 yr, 10 mg/kg (max 1 gm) 2-3 times daily. By continuous IV infusion, 1-18 yr, 45 mg/kg over 24 hr.
Prevention of excessive bleeding after dental procedures (e.g. in haemophilia): INJECTION: By IV injection pre-operatively, Child 6-18 yr, 10 mg/kg (max 1.5 gm). ORAL: Oral: Oral pre-operatively, 6-18 yr, 15-25 mg/kg (max 1.5 gm). Oral postoperatively, 6-18 yr, 15-25 mg/kg (max 1.5 gm) 2-3 times daily for up to 8 days.

One of the following licensed pharmacy from the nearest location will deliver Transmac capsule 250 mg 2×50’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts the your request based on valid prescription and availability.

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