MBBS
Yentreve capsule 20 mg 14’s
- Does this requires a prescription ? Yes
- Generic Name: Duloxetine
- Manufactured by : Shrooq Pharmaceutical Ltd
- Drug Strength : 20 mg
- Drug Form : Capsule
- Pack Size : 14s
- Product SKU : pg_24787_34411
Yentreve capsule contains Duloxetine | belongs to Serotonin and noradrenaline reuptake inhibitor
Alternate brands of Yentreve capsule 20 mg 14’s
Brand Name | Price | Savings |
---|---|---|
Zuloxet capsule 60 mg 10’s | ₨ 380.00 | You will pay -132 more |
Zuloxet capsule 30 mg 10’s | ₨ 240.00 | You can save 8 |
Zuloxet capsule 20 mg 14’s | ₨ 235.00 | You can save 13 |
Zenbar capsule 60 mg 10’s | ₨ 410.00 | You will pay -162 more |
Zenbar capsule 30 mg 10’s | ₨ 300.00 | You will pay -52 more |
How it works
It works by increasing the levels of certain chemical substances in the brain and thus helps in relieving the depressive symptoms.
Side effects
Major & minor side effects for Yentreve capsule 20 mg 14’s
- Nausea
- Sleepiness
- Dry mouth
- Body pain
- Joint pain
- Abnormal ejaculation
- Loose stools
- Shaking of hands or feet
- Heartburn
Uses of Yentreve capsule 20 mg 14’s
What is it prescribed for?
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Major depressive disorder
Yentreve capsule 20 mg 14’s is used to treat the symptoms of depression like feeling sad, irritable and loss of interest in activities.
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Generalized anxiety disorder
Yentreve capsule 20 mg 14’s is used to treat the symptoms of generalized anxiety disorder like feeling restlessness, difficulty in concentrating and irregular heartbeat.
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Diabetic Peripheral Neuropathy
Yentreve capsule 20 mg 14’s is used to relieve the symptoms like pain in the diabetic peripheral neuropathy which is a complication of diabetes characterized by nerve damage.
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Chronic Musculoskeletal Pain
Yentreve capsule 20 mg 14’s is used to relieve chronic low back pain and pain due to osteoarthritis due to wear and tear of muscle tissue during daily activities.
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Fibromyalgia
Yentreve capsule 20 mg 14’s is used to relieve the symptoms like pain in the tender points like neck, shoulders, back, hips, arms, and legs.
Concerns
Frequently asked questions
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Onset of action
The peak effect of this medicine can be observed in 6 to 10 hours.
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Duration of Effect
The effect of this medicine lasts for an average duration of 24 hours.
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Safe with Alchohol?
Yentreve capsule 20 mg 14’s may increase the risk of liver injury if taken with alcohol. Avoid consumption of alcohol. Monitoring of liver enzymes is necessary. Any symptoms of abdominal pain, yellow discolouration of skin and eyes should be reported to the doctor.
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Is it habit forming?
No habit forming tendencies were reported.
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Usage in pregnancy?
This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.
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Usage while breast-feeding?
This medicine is known to excreted through the breast milk. It is not recommended for breastfeeding women unless absolutely necessary. However, monitoring of side effects like drowsiness, weight gain is necessary.
When not to use?
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Allergy
This medicine is not recommended for use if you have a known history of allergy to Yentreve capsule 20 mg 14’s
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Monoamine oxidase inhibitors
Yentreve capsule 20 mg 14’s is not recommended in the patients for at least 14 days after discontinuation of monoamine oxidase inhibitors.
Warnings
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Pregnancy
This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.
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Breast-feeding
This medicine is known to excreted through the breast milk. It is not recommended for breastfeeding women unless absolutely necessary. However, monitoring of side effects like drowsiness, weight gain is necessary.
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Suicidal thoughts
This medicine may increase the risk of suicidal thoughts in the children, adolescents and young adults with the major depressive disorder or other psychiatric disorder. Patient's caretakers should be educated about the symptoms of depression. Any symptoms of change in the behavior should be reported to the doctor.
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Orthostatic Hypotension and fall
This medicine is known to cause orthostatic hypotension especially during the 1st week of the treatment. This effect can increase the risk of fall in the elderly population. Any symptoms of dizziness, unsteady walking should be reported to the doctor.
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Abnormal bleeding
This medicine may increase the risk of bleeding especially in the patients receiving nonsteroidal anti-inflammatory drugs, aspirin, and warfarin. Monitoring of blood cells count should be performed. Any symptoms of abnormal bleeding should be reported to the doctor.
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Low sodium levels
This medicine is known to lower the sodium levels in the body. This risk is more in the elderly population and in the patients receiving diuretics. Monitoring of sodium levels should be performed. Any symptoms of unsteadiness, headache, difficulty in concentration should be reported to the doctor.
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Withdrawal symptoms
This medicine should not be discontinued abruptly. It may cause withdrawal symptoms like dizziness, sleep disturbances and anxiety. Do not stop the use of this medicine without consulting your doctor.
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Skin reactions
This medicine is known to cause rare but serious skin reactions like erythema multiforme and Stevens-Johnson Syndrome. Discontinue the treatment and inform the doctor if symptoms like itching, peeling skin, rashes appear.
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Impaired liver function
This medicine is known to cause an increase in the liver enzymes and severe liver injuries. Discontinue the treatment if any signs and symptoms like increased liver enzymes, abdominal pain appear.
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Impaired kidney function
This medicine should be used with caution in the patients with mild to moderate kidney injury. It is not recommended in the patients with the severe kidney injury (CrCl less than 30 ml/min).
Dosage
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Missed Dose
Take the missed dose as soon as you remember. However, if it is almost time for the next scheduled dose then the missed dose should be skipped.
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Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
Interactions
Interaction with Medicines- Ciprofloxacin severe
- Aspirin moderate
- Diuretics moderate
- Dextromethorphan severe
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moderate
Yentreve capsule 20 mg 14’s should be used with caution in the patients with diabetes mellitus due to the alteration in the blood glucose levels. Monitoring of blood glucose levels is necessary. Any signs and symptoms like increased blood glucose levels, increased urination should be reported to the doctor.
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moderate
Yentreve capsule 20 mg 14’s should be used with caution in the patients with glaucoma due to the increase in the fluid pressure in the eye. Inform the doctor if you have any history of eye disorder. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition.
General Instructions
Take Yentreve capsule 20 mg 14’s as prescribed by the doctor. Do not take this medicine in larger or smaller quantities than recommended. The treatment should be started at lower doses and increase the dose gradually based on the response. Do not stop taking this medicine without informing your doctor.
Other details
- Can be taken with or without food, as advised by your doctor
- To be taken as instructed by doctor
- May cause sleepiness
References
- practo.com - Duloxetine [Internet]. Available from: https://www.practo.com/medicine-info/duloxetine-97-api [cited 16 september 2019]. 16 Nov 2017
- medlineplus.gov - Duloxetine [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a604030.html#overdose [cited 16 september 2019]. 11 September 2019
- dailymed.nlm.nih.gov - Duloxetine [Internet]. Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0a541d20-5466-433b-a104-40a7b2296076#Section_14.4 [cited 16 september 2019]. January 9, 2018
what are the adverse effects of Yentreve capsule 20 mg 14’s?
GI disorders, excessive sweating, CNS disorders e.g. dizziness, fatigue, insomnia, somnolence, blurred vision, dysuria.
What happens if I miss a dose of Yentreve capsule 20 mg 14’s?
Adults: Major depressive disorder Initial & maintenance dose: 60 mg once daily.
Generalized anxiety disorders: 30 mg daily, increased if necessary to 60 mg once daily; max 120 mg daily.
Diabetic peripheral neuropathic pain: 60 mg once daily; max 120 mg in divided doses.
Children: Not recommended.
One of the following licensed pharmacy from the nearest location will deliver Yentreve capsule 20 mg 14’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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