₨ 842.02
MBBS
Zinacef tablet 250 mg 14’s
- Does this requires a prescription ? Yes
- Generic Name: Cefuroxime
- Manufactured by : Glaxosmithkline
- Drug Strength : 250 mg
- Drug Form : Tablet
- Pack Size : 14s
- Product SKU : pu_pg_25138_34977
Zinacef tablet contains Cefuroxime | belongs to Cephalosporin
Alternate brands of Zinacef tablet 250 mg 14’s
| Brand Name | Price | Savings |
|---|---|---|
| Zinorox Injection 750 mg 1 Vial | ₨ 105.00 | You can save 737.02 |
| Zinorox Injection 250 mg 5 Vial | ₨ 145.00 | You can save 697.02 |
| Zinacef tablet 125 mg 14’s | ₨ 295.72 | You can save 546.3 |
| Zerox suspension 125 mg 50 mL | ₨ 190.00 | You can save 652.02 |
| Zeolot Injection 1.5 gm 1 Vial | ₨ 180.00 | You can save 662.02 |
How it works
Zinacef tablet 250 mg 14’s stops the growth and multiplication of bacteria.
Side effects
Major & minor side effects for Zinacef tablet 250 mg 14’s
- Diarrhea severe
- Chills severe
- Headache severe
- Change in taste
- Chest pain severe
- Difficult or painful urination severe
- Shortness of breath severe
- Stomach pain rare
Uses of Zinacef tablet 250 mg 14’s
What is it prescribed for?
-
Pharyngitis/Tonsilitis
This medicine is used for the treatment of infections of the throat and airways leading to the lungs, namely tonsillitis and pharyngitis, caused by bacteria such as Streptococcus pyogenes.
-
Ear Infection (Otitis Media)
This medicine is used in the treatment of otitis media (middle ear infection) caused by bacteria such as Streptococcus pneumoniae, Haemophilus influenzae, staphylococci, Streptococcus pyogenes, etc.
-
Sinusitis
This medicine is used for the treatment of sinusitis, which is an inflammation of the sinuses, caused by bacteria such as Streptococcus pneumoniae, Haemophilus influenzae, etc.
-
Bronchitis
This medicine is used for the treatment of bronchitis, which is an inflammation of the lining of the bronchial tubes, caused by bacteria such as Streptococcus pneumoniae, Haemophilus influenzae, etc.
-
Skin and Soft tissue infections
This medicine is used in the treatment of skin or soft tissue infections caused by bacteria such as Staphylococcus aureus, Streptococcus pyogenes, etc.
-
Urinary Tract Infection
This medicine is used in the treatment of uncomplicated urinary tract infections caused by bacteria such as Pseudomonas aeruginosa, Proteus mirabilis, Escherichia coli, etc.
-
Lyme disease
This medicine is used in the treatment of Lyme disease, which is a bacterial infection caused by Borrelia burgdorferi. This disease may be associated with symptoms such as a fever, skin rashes with a bulls-eye pattern, growing area of skin redness, etc.
-
Gonococcal Infection
This medicine is used in the treatment of a gonococcal infection caused by Neisseria gonorrhoeae.
Concerns
Frequently asked questions
-
Onset of action
The amount of time required for this medicine to show its action is not clinically established.
-
Duration of Effect
The amount of time for which this medicine remains active in the body is not clinically established.
-
Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
-
Is it habit forming?
No habit-forming tendencies were reported.
-
Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking/receiving this medicine.
-
Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving/taking this medicine. If the medicine is used, close monitoring of the infant for any undesired side effects is necessary.
When not to use?
-
Allergy
This medicine is not recommended for use if the patient has a known allergy to Zinacef tablet 250 mg 14’s or any other Beta-lactam antibiotics like penicillins and cephalosporins.
Warnings
-
Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking/receiving this medicine.
-
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving/taking this medicine. If the medicine is used, close monitoring of the infant for any undesired side effects is necessary.
-
Clostridium difficile-associated DiarrheaImpaired kidney function
Antibiotic therapy will cause an imbalance in the normal microbial flora of the large intestine, which may promote the growth of a bacteria called Clostridium difficile and you may experience severe diarrhea as a result. Report any such incidence to the doctor on priority and avoid usage of this medicine in these cases.
-
Impaired kidney function
This medicine should be used with caution in patients with a known history of renal impairment due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.
-
Drug-resistance
Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.
-
Use in pediatrics
Use of Zinacef tablet 250 mg 14’s is not recommended for infants less than 3 months of age.
-
Jarisch-Herxheimer reaction
This medicine may cause Jarisch-Herxheimer reaction in some patients when it is used for treating Lyme disease. This reaction is characterized by symptoms such as fever, chills, headache, dizziness, increased heart rate, etc. This reaction usually subsides on its own. Appropriate corrective measures or dose adjustments may be necessary based on the clinical condition of the patient.
Dosage
-
Missed Dose
Oral forms: The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not double your dose to make up for the missed one. Injection: Since this medicine is administered by a qualified healthcare professional in the clinical or hospital setting, the likelihood of a missed dose is very low.
-
Overdose
Oral forms: Seek emergency medical attention or contact your doctor in case of an overdose. Injection: Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
Interactions
Interaction with Medicines- Amikacin moderate
- Chloramphenicol moderate
- Ethinyl Estradiol moderate
- Cholera Vaccine severe
- Furosemide moderate
- Probenecid moderate
- Dicumarol moderate
- Warfarin moderate
- Aluminum hydroxide moderate
-
moderate
This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis, since it may worsen the patient's condition. Report any incidence of severe diarrhea, abdominal pain, blood in stools, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.
-
moderate
This medicine should be used with caution in patients with a history of liver diseases or a family history of liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is recommended during treatment with this medicine. Report any undesired side effects to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
-
moderate
This medicine should be used with caution in patients with a history of seizure disorder or a family history of seizures due to the increased risk of recurrent seizures. Therapy should be discontinued if the patient experiences a seizure episode due to this medicine. Appropriate corrective measures and/or replacement with a suitable alternative may be necessary in some cases based on the clinical condition of the patient.
-
severe
This medicine should be used with extreme caution in patients with a known history of renal diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
General Instructions
Oral forms: Take this medicine as advised by your doctor. You may take this medicine with or without food. Do not take in larger amounts than advised. Injection: This medicine should be administered by a qualified healthcare professional in the clinical or hospital setting. Inform the doctor if you have a known history of allergy to this medicine. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine. Report any undesired side effects to the doctor promptly.
Other details
- Can be taken with or without food, as advised by your doctor
- To be taken as instructed by doctor
- Does not cause sleepiness
References
- practo.com - Cefuroxime [Internet]. Available from: https://www.practo.com/medicine-info/cefuroxime-52-api [cited 13 september 2019]. 4 Jun 2018
- dailymed.nlm.nih.gov - CEFUROXIME AXETIL [Internet]. Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=faef39e9-d793-4191-a728-310f6fab759d [cited 13 september 2019]. September 9, 2019
- medlineplus.gov - Cefuroxime [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a601206.html [cited 13 september 2019]. 11 september 2019
- medicines.org.uk - Cefuroxime [Internet]. Available from: https://www.medicines.org.uk/emc/medicine/22534#PRODUCTINFO [cited 13 september 2019]. 02 Aug 2016
How to use Zinacef tablet 250 mg 14’s
IM: Inject deep IM into large muscle mass. IV: Inject direct IV over 3-5 min. Infuse intermittent infusion over 15-30 min.
Reconstitution: IM: Add 3 or 3.6 mL SWFI to each 750 mg vial to yield 220 mg/mL.
Compatibility: Stable in D5¼NS, D5½NS, D5NS, D5W, D10W, LR, NS.
Stability: Reconstituted solution is stable for 24 hours at room temperature and 48 hours when refrigerated. For IV infusion in NS or D5W, solution is stable for 24 hours at room temperature, 1 week when refrigerated, or 26 weeks when frozen.
what are the adverse effects of Zinacef tablet 250 mg 14’s?
Hypersensitivity reactions, Gl disturbances. Rarely pain at inj site, candidiasis, eosinophilia, neutropenia, leucopenia, transient rise in liver enzymes, blood urea. Positive Coomb’s test, headache, dizziness, candida overgrowth, decreased haemoglobin, pseudomembranous colitis, haemolytic anaemia.
What happens if I miss a dose of Zinacef tablet 250 mg 14’s?
ORAL: Adults: Most infections and bronchitis, usually 250 mg twice daily.
Severe infections and pneumonia: 500 mg twice daily.
Gonorrhoea: 1 gm as a single dose. Children: 3-6 mth (4-6 kg body wt): 40-60 mg; 6 mth-2 yr, 60-120 mg; 2-12 yr: 125 mg. All twice daily.
Lower Respiratory Infection: Adults & Children: gt;13 yr: 250-500 mg twice daily for 5-10 days.
Upper Respiratory Infection: Pharyngitis/Tonsillitis/ Sinusitis: Adults: 250 mg every 12 hr for 10 days. Children: gt;13 yr: 250 mg every 12 hr for 10 days.
Pharyngitis/Tonsillitis: Children: 3 mth-12 yr, 125 mg every 12 hr for 10 days or 10 mg/kg every 12 hr for 10 days. Max: 500 mg/day.
Sinusitis: Children: 3 mth-12 yr, 250 mg every 12 hr for 10 days or 15 mg/kg every 12 hr for 10 days. Max: 1 gm/day.
Otitis Media: Children: 3 mth-12 yr: 15 mg/kg every 12 hr for 10 days. Max: 1 gm/day.
Urinary Tract Infection: Adults & Children: gt; 13 yr: 125-250 mg every 12 hr for 7-10 days.
INJECTION: Adults: Usually 750 mg three times daily by IM or IV inj, can be increased in severe infections to 1.5 gm three times daily by IV inj. Infants & Children: 30-100 mg/kg/day in 3-4 divided doses. Neonates: 30-100 mg/kg/day in 2-3 divided doses.
Bone Infection: IM/IV: Adults: 1.5 gm every 8 hr. Children: gt; 3 mth: 50 mg/kg every 8 hr. Max: 4.5 gm/day.
Meningitis: IV: Adults: 1.5 gm every 6 hr. Max: 3 gm every 8 hr. Children: gt; 3 mth: 200-240 mg/kg/day divided every 6-8 hr.
Septicaemia: IV: Adults: 1.5 gm every 6-8 hr. Children: gt; 3 mth: 100 mg/kg/day given every 6-8 hr. Max: 4.5 gm/day.
One of the following licensed pharmacy from the nearest location will deliver Zinacef tablet 250 mg 14’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
Questions and Answers
There are no questions yet. Be the first to ask a question about this product.
Related products
- MedicalStore.ae
- MedicalStore.com.pk
Products listed on medicalstore.com.pk are 100% genuine and sourced from licensed pharmacies.
We work hard to bring you unimaginable discounts without compromising on quality.
We uses SSL (standard security technology) to ensure data privacy of all our customers.
Reviews
There are no reviews yet.