₨ 3,881.00
MBBS
Bioral capsule 50 mg 50’s
- Does this requires a prescription ? Yes
- Generic Name: cyclosporin
- Manufactured by : Allmed Labs
- Drug Strength : 50 mg
- Drug Form : Capsule
- Pack Size : 50s
- Product SKU : pg_2920_3812
Bioral capsule contains Cyclosporin | belongs to Immunosuppressant
Alternate brands of Bioral capsule 50 mg 50’s
Brand Name | Price | Savings |
---|---|---|
Sandimmun Injection 250 mg 10 Ampx5 mL | ₨ 5,164.58 | You will pay -1283.58 more |
Sandimmun Neoral D Oral Soln 100 mg/mL 50 mL | ₨ 6,951.36 | You will pay -3070.36 more |
Sandimmun Neoral capsule 100 mg 50’s | ₨ 7,756.32 | You will pay -3875.32 more |
Sandimmun Neoral capsule 25 mg 50’s | ₨ 2,900.00 | You can save 981 |
Neocyspin Oral Soln 100 mg 50 mL | ₨ 6,951.00 | You will pay -3070 more |
How it works
Bioral capsule 50 mg 50’s works by decreasing the body's immune system activity and helps in preventing body's rejection action of transplanted organs.
Side effects
Major & minor side effects for Bioral capsule 50 mg 50’s
- Decrease in blood cell count severe
- Tremors severe
- Headache severe
- Nausea and Vomiting severe
- Skin rash severe
- Fever and chills severe
- Abdominal discomfort
- Facial hair growth
- Running Nose
- Muscle cramps
Uses of Bioral capsule 50 mg 50’s
What is it prescribed for?
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Organ Transplant - Rejection Prophylaxis
Bioral capsule 50 mg 50’s is used to reduce the immune response of the body in organ transplant patients.
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Rheumatoid Arthritis
Bioral capsule 50 mg 50’s is used to relieve symptoms of inflammation in Rheumatoid Arthritis patients.
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Psoriasis
Bioral capsule 50 mg 50’s is used in the treatment of psoriasis which is a skin disease characterized by red, scaly patches on the skin.
Concerns
Frequently asked questions
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Onset of action
The effect of this medicine can be observed in 1 to 2 hours.
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Duration of Effect
The effect of this medicine lasts for an average duration of 10 to 27 hours.
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Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
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Is it habit forming?
No habit forming tendency has reported.
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Usage in pregnancy?
This medicine is not recommended for pregnant women.
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Usage while breast-feeding?
This medicine is not recommended in breastfeeding women.
When not to use?
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Allergy
Not recommended in patients with known allergy to Bioral capsule 50 mg 50’s .
Warnings
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Pregnancy
This medicine is not recommended for pregnant women.
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breast-feeding
This medicine is not recommended in breastfeeding women.
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Malignancy
This medicine may increase the risk of lymphoma and other malignancies. Doctors should inform patients about these risks and advise the patient to prevent exposure to sunlight by wearing protective clothes.
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Serious infections
The chances of developing infections are higher in the patients receiving this medicine. Hold the treatment and start with broad-spectrum antibiotics if there are any signs and symptoms of fever. Close monitoring of the body temperature and the blood cell count is necessary.
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Kidney impairment
This medicine is not recommended in the patients with a history of kidney impairment. Close monitoring of kidney function is necessary. The dose should be adjusted based on the creatinine clearance (CrCl).
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Liver impairment
This medicine is not recommended in patients with a history of liver impairment. The concentration of this medicine may increase in such patients. The baseline of the liver function tests should be obtained before starting the treatment.
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Hyperkalemia
This medicine may increase the levels of potassium in the body and may increase the risk of arrhythmia. Close monitoring of potassium levels is necessary. Medicines that can increase potassium levels like ACE inhibitors and potassium-sparing diuretics should be avoided.
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Hypertension
Use with caution in hypertensive patients. Appropriate antihypertensives should be administered to control the blood pressure. Do not use medicine that may increase the potassium levels.
Dosage
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Missed Dose
The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost the time for the next dose.
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Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
Interactions
Interaction with Medicines- Amlodipine moderate
- Atorvastatin severe
- Nonsteroidal anti-inflammatory drugs moderate
- Live attenuated vaccines and related products severe
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Consumption of grapefruit juice is not recommended while receiving this medicine. It may increase the Bioral capsule 50 mg 50’s concentration and increase the risk of liver and kidney injury. It is advised to consult the doctor for a proper diet management before receiving this medicine.
General Instructions
Take Bioral capsule 50 mg 50’s under the supervision of a qualified healthcare professional. Do not take in larger amounts than advised. It is advised to take this medicine at the same time every day. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine without consulting your doctor.
Other details
- Can be taken with or without food, as advised by your doctor
- To be taken as instructed by doctor
- Does not cause sleepiness
References
- practo.com - Cyclosporin [Internet]. Available from: https://www.practo.com/medicine-info/cyclosporine-327-api [cited 17 october 2019]. 5 Jan 2018
- drugbank.ca - Cyclosporin [Internet]. Available from: https://www.drugbank.ca/drugs/DB00091 [cited 17 october 2019]. October 16, 2019
- dailymed.nlm.nih.gov - Cyclosporin [Internet]. Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=bfca7088-fe93-abb9-3ec3-e6f5710a69c6 [cited 17 october 2019]. November 22, 2017
what are the adverse effects of Bioral capsule 50 mg 50’s?
Hyperlipidaemia, hyper-uricaemia, hyperkalaemia, hypomagnesaemia, tremor, headache, paraesthesia, hypertension (discontinue if cannot control), GI upset, anorexia, abdominal pain, gingival hypertrophy, hepatic and renal dysfunction, hypertrichosis, muscle cramps, myalgia, fatigue, anaemia, thrombocytopenia, signs of encephalopathy, rash, oedema, weigh gain, malignancies, Iymphoproliferative disorders, infections. Rarely, micro-angiopathic Haemolytic anaemia or haemolytic uraemic syndrome, menstrual disturbances, gynaecomastia, hyperglycaemia, motor polyneuropathy, pancreatitis, muscle weakness, myopathy, optic disc oedema. Risk of benign intracranial hypertension; investigate patients presenting with signs of raised intracranial pressure, withdraw cyclosporin if diagnosed.
What happens if I miss a dose of Bioral capsule 50 mg 50’s?
Organ transplantations: Used alone, Adults & Children over 3 mth: 10-15 mg/kg by mouth 4-12 yr before transplantations followed by 10-15 mg/kg daily for 1-2 wk postoperatively then reduced gradually to 2-6 mg/kg daily for maintenance (dose should be adjusted according to blood-cyclosporin concentration and renal function); dose lower if given concomitantly with other immunosuppressant therapy; if necessary one-third corresponding oral dose can be given by IV infusion over 2-6 hr.
Bone marrow transplantation; prophylaxis and treatment of graft versus-host disease: Adults & Children over 3 mth: 3-5 mg/kg daily by IV infusion over 2-6 hr from day before transplantation to 2 wk postoperatively (or 12.5-15 mg/kg daily by mouth) then 12.5 mg/kg daily by mouth for 3-6 mth then tailed off (may take up to a yr after transplantation).
Nephrotic syndrome: Adults: Orally, 5 mg/kg daily in 2 divided doses. Children: 6 mg/kg daily in 2 divided doses.
Atopic dermatitis: Adults: Orally, initially 2.5 mg/kg daily in 2 divided doses, if good initial response not achieved within 2 wk. Increase rapidly to max 5 mg/kg daily; initial dose of 5 mg/kg daily in 2 divided doses if very severe. Children: Not recommended.
Severe psoriasis: Adults: Orally, initially 2.5 mg/kg daily in 2 divided doses, increase gradually to max 5 mg/kg daily if no improvement within 1 mth (discontinue if response still insufficient after 6 wk); initial dose of 5 mg/kg daily justified if condition requires rapid improvement. Children: Not recommended.
Severe arthritis: Adults: Orally, initially 2.5 mg/kg daily in 2 divided doses, if necessary increased gradually after 6 wk; max 4 mg/kg daily (discontinue if response insufficient after 3 mth); dose adjusted according to response for maintenance and treatment reviewed after 6 mth. Children: Not recommended.
One of the following licensed pharmacy from the nearest location will deliver Bioral capsule 50 mg 50’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
Questions and Answers
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1 review for Bioral capsule 50 mg 50’s
Anonymous –
submitted 5 stars.