Magnessium Sulphate Injection 5 Ampx2 mL

 19.07

Manufactured by:
Active Pharmaceutical Ingredient:

Drug Form : Injection
Pack Size : 5 Ampx2 mL

Magnessium Sulphate Injection contains Magnesium Sulphate, Inj | belongs to Electrolyte

SKU: pg_13756_19110 Categories: ,

Alternate brands of Magnessium Sulphate Injection 5 Ampx2 mL

Brand Name Price Savings
Magnessium Sulphate Injection 1 Ampx10 mL  15.76 You can save 3.31
Mag-S Injection 10 Ampx2 mL  36.00 You will pay -16.93 more
List of alternate brands

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How it works

Magnessium Sulphate Injection 5 Ampx2 mL corrects the magnesium levels in the blood. It decreases acetylcholine release, inhibits action potentials in the myocardium, favors movement of calcium, potassium, and sodium in and out of cells and also works by stabilizing the brain cells.

Side effects

Major & minor side effects for Magnessium Sulphate Injection 5 Ampx2 mL

  • Difficulty in breathing
  • Swelling of eyelids, face, lips
  • Itching and rash
  • Dizziness and Drowsiness
  • Pain at the injection site
  • Muscle weakness
  • Excessive thirst
  • Slurred speech

Uses of Magnessium Sulphate Injection 5 Ampx2 mL

What is it prescribed for?

  • Hypomagnesemia

    This medicine is used to correct the magnesium levels in patients with low magnesium levels in the body when the patient is not able to tolerate oral supplements.

  • Toxemia of Pregnancy

    This medicine is used for the prevention and control of seizures associated with pre-eclampsia (a pregnancy complication characterized by increased blood pressure and protein in the urine) and eclampsia (a condition where there is an occurrence of seizures in pregnant women with severe preeclampsia).

  • Atrial tachycardia

    This medicine is used for the treatment of patients with atrial tachycardia, a type of heart rhythm abnormality characterized by a constant rate of more than 100 beats per minute.

  • Seizures

    This medicine is used for the control of seizures.

Concerns

Frequently asked questions

  • Onset of action

    Anticonvulsant effect: The effect of this medicine can be observed within1 hour of intramuscular administration of dose and immediately after intravenous administration of dose.

  • Duration of Effect

    Anticonvulsant effect: The effect of this medicine lasts for an average duration of 3 to 4 hours after intramuscular administration and 30 minutes after intravenous administration of the dose.

  • Safe with Alchohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    No habit-forming tendencies were reported.

  • Usage in pregnancy?

    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

  • Usage while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

When not to use?

  • Allergy

    This medicine is not recommended for use in patients with a known allergy to Magnessium Sulphate Injection 5 Ampx2 mL or any other inactive ingredients present in the formulation.

  • Hypermagnesemia

    This medicine is not recommended for use in patients with hypermagnesemia (high blood magnesium levels) due to the increased risk of adverse effects.

  • Hypercalcemia

    This medicine is not recommended for use in patients with hypercalcemia (high levels of calcium in the blood) due to the risk of worsening of the patient's condition.

  • Myocardial damage

    This medicine is not recommended for use in patients with myocardial damage due to the risk of worsening of the patient's condition.

  • Diabetic coma

    This medicine is not recommended for use in patients with diabetic coma due to the risk of worsening of the patient's condition.

Warnings

Warnings for special population
  • Pregnancy

    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

  • Breast-feeding

    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

General Warnings
  • Hypermagnesaemia

    Use of this medicine may increase the magnesium levels in the blood. The risk is especially higher in patients suffering from kidney diseases. Report any symptoms such as flushing of the skin, increased thirst, difficulty in breathing, changes in heart rate, etc. to the doctor immediately. Close monitoring of magnesium levels, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

  • Other uses

    Your doctor may prescribe this medicine for indications other than those stated above in certain specific circumstances, especially if other medicines are not effective. All the risks and benefits should be discussed with the doctor in such cases.

  • Liver impairment

    This medicine should be used with caution in patients with liver impairment due to the risk of worsening of the patient's condition. Close monitoring of liver function is recommended while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative might be required in some cases.

Dosage

  • Missed Dose

    Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

  • Overdose

    Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

Interactions

Interaction with Medicines
  • Atracurium moderate
  • Raltegravir moderate
  • Nifedipine moderate
  • Cisatracurium moderate
Disease interactions
  • severe

    This medicine should be used with caution in patients suffering from kidney function impairment due to the increased risk of severe adverse effects. Close monitoring of kidney function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

General Instructions

This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.

Other details

  • Usage does not depend on food timings
  • To be taken as instructed by doctor
  • Effect on sleep is not established

References

Additional Information>

How to use Magnessium Sulphate Injection 5 Ampx2 mL

IV: Concentration of magnesium sulphate should not exceed 20% of dilution.
Compatibility: Stable in D5W, NS, mannitol, KCl.
Y-site administration:
Drug to Drug IV Compatibility: Acyclovir, amikacin, aztreonam, bumetanide, calcium gluconate, cisatracurium, dexamethasone, diltiazem, diphenhydramine, dopamine, enalapril, epinephrine, esmolol, famotidine, fentanyl, fluconazole, gentamicin, heparin, hydromorphone, imipenem, insulin regular, labetalol, levofloxacin, linezolid, lorazepam, meropenem, metoclopramide, metronidazole, midazolam, milrinone, morphine, nitroglycerin, nitroprusside, norepinephrine, phenylephrine, piperacillin/tazobactam, propofol, tobramycin, vancomycin, vasopressin.
Drug to Drug IV Incompatibility: Cefepime, ceftriaxone, ciprofloxacin, lansoprazole, methylprednisolone.

what are the adverse effects of Magnessium Sulphate Injection 5 Ampx2 mL?

Associated with hypermagnesaemia, nausea, vomiting, thirst, flushing of skin, hypotension, arrhythmias, coma, respiratory depression, drowsiness, confusion, loss of tendon reflexes, muscle weakness; colic and diarrhoea following oral administration.

What happens if I miss a dose of Magnessium Sulphate Injection 5 Ampx2 mL?

Eclampsia: Adults: Initially IV 4 gm of magnesium sulphate (approx 16 mmol Mg) over 20 min followed by IV infusion at a rate of 1 gm magnesium sulphate every hr. Recurrence of seizures may require an additional IV bolus of 2-4 gm magnesium sulphate.
Arrhythmias: Adults: IV injection of 8 mmol magnesium over 10-15 min, repeated if necessary.
Myocardial infarction: Adults: IV injection of 8 mmol magnesium over 20 min, followed by IV infusion of 65-72 mmol of magnesium over the following 24 hr.
Magnesium deficiency and hypomagnesaemia: Adults: 50 mmol of magnesium orally daily adjusted according to individual response. In acute or severe hypomagnesaemia: 35-50 mmol of magnesium by slow IV infusion (in glucose 5%) on the first day followed by 25 mmol daily until the hypomagnesaemia is corrected; up to a total of 160 mmol may be required. Alternatively by IM or slow IV.

One of the following licensed pharmacy from the nearest location will deliver Magnessium Sulphate Injection 5 Ampx2 mL. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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