₨ 24,200.00
MBBS
Reopro Injection 10 mg 1 Vial
Reopro Injection contains Abciximab | belongs to Antiplatelet
Alternate brands of Reopro Injection 10 mg 1 Vial
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|---|---|---|
| Test Product with Variation | ₨ 100.00 – ₨ 690.00 | You can save 24100 |
How it works
Reopro Injection 10 mg 1 Vial works by preventing the formation of blood clots during certain specific surgical procedures.
Side effects
Major & minor side effects for Reopro Injection 10 mg 1 Vial
- Bleeding Severe
- Blurred vision Severe
- Dizziness when getting up suddenly from a sitting position
- Excessive sweating
- Unusual tiredness or weakness
- Black or tarry stools Severe
- Bleeding gums Severe
- Pinpoint red spots on skin
- Chest pain or discomfort
- Fever and chills
- Eye pain and discomfort rare
- Headache
- Pale skin Severe
- Rapid weight gain
- Swelling of hands and feet Severe
Uses of Reopro Injection 10 mg 1 Vial
What is it prescribed for?
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Percutaneous Coronary Intervention
This medicine is used as an adjunct in patients undergoing surgical procedures including percutaneous coronary intervention, balloon angioplasty, stent placement, etc. to prevent the formation of blood clots and associated complications.
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Unstable angina
This medicine is used to treat patients with unstable angina who are unresponsive to conventional therapy and who are scheduled to undergo percutaneous coronary intervention within 24 hours.
Concerns
Frequently asked questions
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Onset of action
The effect of this medicine can be observed within 10 minutes of administration of the dose.
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Duration of Effect
The effect of this medicine lasts for an average duration of 72 hours.
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Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
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Is it habit forming?
No habit-forming tendencies were reported.
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Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless absolutely necessary. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine.
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Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine.
When not to use?
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Allergy
This medicine is not recommended for use in patients with a known allergy to Reopro Injection 10 mg 1 Vial or any other inactive ingredients present along with it.
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Cerebrovascular accident
This medicine is not recommended for use in patients with a history of cerebrovascular accidents within the past 2 years due to the increased risk of worsening of the patient’s condition.
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Active bleeding
This medicine is not recommended for use in patients with active internal bleeding due to the increased risk of worsening of the patient’s condition.
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Thrombocytopenia
This medicine is not recommended for use in patients with thrombocytopenia (abnormally low number of platelets) due to the increased risk of worsening of the patient’s condition.
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Uncontrolled hypertension
This medicine is not recommended for use in patients with severe uncontrolled hypertension due to the increased risk of worsening of the patient’s condition.
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Oral anticoagulants
This medicine is not recommended for use in patients who have recently received any oral anticoagulants (within the past 7 days), unless the prothrombin time is lesser than or equal to 1.2, due to the increased risk of excessive bleeding.
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Peptic Ulcer
This medicine is not recommended for use in patients with peptic ulcer disease due to the increased risk of worsening of the patient’s condition.
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Intracranial neoplasm
This medicine is not recommended for use in patients suffering from an intracranial neoplasm due to the increased risk of worsening of the patient’s condition.
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Major surgery
This medicine is not recommended for use in patients who have undergone major surgery or trauma within the past 6 weeks due to the increased risk of worsening of the patient’s condition.
Warnings
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Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine.
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Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine.
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Bleeding
This medicine should be used with extreme caution in patients with increased risk of bleeding events. The risk of bleeding is higher if the patient is taking any anticoagulant medicines. An alternative treatment option may be necessary in some cases based on the clinical condition.
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Other medicines
Reopro Injection 10 mg 1 Vial may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before receiving this medicine.
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Allergic reactions
Use of this medicine may sometimes cause a potentially fatal allergic reaction. Therapy should be discontinued immediately if the patient suffers from severe allergic reactions.
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Thrombocytopenia
Use of this medicine may cause a decrease in blood platelet levels. It is advised to monitor the blood platelet count prior to and during treatment with this medicine. An alternative treatment option may be necessary in some cases based on the clinical condition.
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Laboratory tests
It is advised to identify pre-existing hemostatic abnormalities using appropriate laboratory tests before initiating the treatment course with this medicine.
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Use in children
This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.
Dosage
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Missed Dose
Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.
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Overdose
Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
Interactions
Interaction with Medicines- Enoxaparin severe
- Vitamin E moderate
- Heparin severe
- Alteplase severe
- Bivalirudin moderate
- Dabigatran severe
- Streptokinase severe
- Anisindione severe
- Dipyridamole severe
- Celecoxib moderate
- Citalopram severe
- Desvenlafaxine moderate
- Apixaban severe
- Ibuprofen moderate
- Fondaparinux severe
- Diclofenac moderate
- Aspirin moderate
- Acalabrutinib severe
- Ardeparin severe
General Instructions
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Other details
- Usage does not depend on food timings
- Does not cause sleepiness
- To be taken as instructed by doctor
References
- drugbank - Abciximab [Internet]. Available from: https://go.drugbank.com/drugs/DB00054 [cited 1/12/2021]. 2021
How to use Reopro Injection 10 mg 1 Vial
Bolus dose: Aseptically withdraw the necessary amount of abciximab (2 mg/ mL) for the bolus dose through a 0.22 micron filter into a syringe; the bolus should be administered 10-60 min before procedure. Continuous infusion: Aseptically withdraw 4.5 mL (9 mg) of abciximab for the infusion through a 0.22 micron filter into a syringe; inject this into 250 mL of NS or D5W to make a solution with a final concentration of 35 mcg/ mL. Infuse at a rate of 17 mL/hour (10 mcg/min) for 12 hour via pump; filter all infusions.
what are the adverse effects of Reopro Injection 10 mg 1 Vial?
Bleeding complications, hypertension, nausea, vomiting thrombocytopenia, haematoma, bradycardia, fever, vascular disorders.
What happens if I miss a dose of Reopro Injection 10 mg 1 Vial?
Ischaemic cardiac complication: Adults: 0.25 mg/kg by bolus IV inj. 10-60 min prior to PTCA and immediately followed by a 0.125 mcg/kg/min. continuous IV infusion for 12 hr.
Unstable angina: Adults: 0.25 mg/kg by bolus IV inj up to 24 hr prior to PTCA and immediately followed by a 0.125 mcg/kg/min. continuous IV infusion for 12 hr after the intervention. Administer oral aspirin at a dose of not less than 300 mg daily. Administer Heparin in a low-dose weight adjusted regimen: see literature.
Elderly: Over 80 yr, not recommended.
Children: Not recommended.
One of the following licensed pharmacy from the nearest location will deliver Reopro Injection 10 mg 1 Vial. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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