
MBBS
Tofranil tablet 25 mg 20×10’s
- Does this requires a prescription ? Yes
- Generic Name: Imipramine
- Manufactured by : INDUS PHARMA (PVT) LTD.
- Drug Strength : 25 mg
- Drug Form : Tablet
- Pack Size : 20x10s
- Product SKU : pu_pg_22794_31575
Tofranil tablet contains Imipramine | belongs to Tricyclic antidepressant (TCAD)
Alternate brands of Tofranil tablet 25 mg 20×10’s
Brand Name | Price | Savings |
---|---|---|
Mild tablet 75 mg 10×10’s | ₨ 210.00 | You can save 125.64 |
Mild tablet 25 mg 10×10’s | ₨ 80.00 | You can save 255.64 |
Medpramine tablet 25 mg 10×10’s | ₨ 80.00 | You can save 255.64 |
Imral tablet 25 mg 10×10’s | ₨ 80.00 | You can save 255.64 |
Imiprol tablet 75 mg 5×20’s | ₨ 250.00 | You can save 85.64 |
How it works
Tofranil tablet 25 mg 20×10’s works by restoring the balance of certain natural substances (neurotransmitters such as norepinephrine) in the brain. For bed-wetting, this medication may work by blocking the effect of a certain natural substance (acetylcholine) on the bladder.
Side effects
Major & minor side effects for Tofranil tablet 25 mg 20×10’s
- Abdominal pain rare
- Blurred vision rare
- Decrease in frequency of urination rare
- Dry mouth rare
- Rapid weight gain rare
- Yellow colored eyes or skin rare
- Unusual tiredness and weakness rare
- Increased sensitivity of the eyes to sunlight rare
- Skin rash rare
Uses of Tofranil tablet 25 mg 20×10’s
What is it prescribed for?
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Depression
This medicine is used to relieve symptoms of depression characterized by sadness, loss of interest, irritability, and sleeplessness.
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Enuresis
This medicine may also be used for temporary adjunctive therapy to reduce enuresis (bedwetting) while sleeping in children.
Concerns
Frequently asked questions
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Onset of action
The amount of time required for this medicine to show its action is not clinically established.
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Duration of Effect
The amount of time for which this medicine remains active in the body is not clinically established.
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Safe with Alchohol?
Consumption of alcohol during treatment with this medicine may increase the risk of severe side effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, and fainting. It is advised that you should avoid alcohol and not to perform activities which require high mental alertness like driving a vehicle and operating machinery when taking these medicines together.
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Is it habit forming?
No habit forming tendencies were reported.
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Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
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Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
When not to use?
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Allergy
This medicine is not recommended for use in patients with a known allergy to Tofranil tablet 25 mg 20×10’s or any other inactive ingredients present in the formulation.
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Monoamine oxidase inhibitors (MAOI)
This medicine is not recommended for use in patients taking monoamine oxidase inhibitors (MAOI) due to the increased risk of serious and life-threatening side effects. A time gap of at least 14 days should be maintained between stopping therapy with MAOIs and starting therapy with this medicine.
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Myocardial infarction
This medicine is not recommended for use in patients who have had an episode of heart-attack in recent times or recovering from it due to the increased risk of worsening of patients.
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Driving or operating machinery
This medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.
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Suicidal tendencies
This medicine should be used with caution due to the increased risk of suicidal tendencies. This risk is especially higher in young adult patients. Patients should be closely monitored for any change in mood or behavior. Report any such incidence to the doctor so that counseling and monitoring of progress can be performed at regular intervals. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
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Withdrawal symptoms
The use of this medicine should not be discontinued abruptly. You may experience withdrawal symptoms especially if you have been using a high dose for a long duration. Do not stop the use of this medicine without consulting your doctor.
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Surgery
Use of this medicine is not recommended if you are planning to undergo a surgery in near future. Consult your doctor in this regard so that it can be discontinued properly.
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Bipolar disorder
This medicine is not recommended in patients with bipolar disorder. Symptoms of mania and depression can worsen upon usage of this medicine. Consult your doctor and report the incidence of bipolar depression or mania before receiving this medicine.
Dosage
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Missed Dose
Take the missed dose as soon as you remember. However, if it is almost time for the next scheduled dose then the missed dose should be skipped.
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Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
Interactions
Interaction with Medicines- Antihypertensives moderate
- Selegiline severe
- Codeine moderate
- Sunitinib moderate
- Ondansetron severe
- Rufinamide moderate
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severe
This medicine should be used with caution in patients with a history of cardiovascular diseases due to the increased risk of severe side effects. These side effects may include an increased heart rate, arrhythmias, heart block, and tachycardia. Close monitoring of heart function and vital signs is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
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severe
This medicine should be administered with extreme caution in patients suffering from Pheochromocytoma, the risk of severe to fatal change in blood pressure is very high. An alternative treatment option should be considered in some cases based on the clinical condition.
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severe
This medicine should be used with caution in patients with a history of seizure disorder due to the increased risk of recurrent seizures. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
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moderate
This medicine should be used with caution since it may alter blood glucose levels in diabetic patients. Close monitoring of blood glucose levels is recommended for such patients. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
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moderate
This medicine should be used with caution if you have glaucoma. Use of this medicine can worsen the symptoms of both closed and open-angle glaucoma. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
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moderate
This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
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moderate
This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of the liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
General Instructions
Take this medicine exactly advised by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable effects. Do not stop taking this medicine before completion of the course/without consulting your doctor.
References
- webmd.com - Imipramine [Internet]. Available from: https://www.webmd.com/drugs/2/drug-8664/imipramine-oral/details [cited 9/7/2020].
How to use Tofranil tablet 25 mg 20×10’s
UNLICENSED USE
Children: Attention deficit hyperactivity disorder: 6-18 yr, 10-30 mg twice daily.
what are the adverse effects of Tofranil tablet 25 mg 20×10’s?
Anticholinergic effects, (e.g. dry mouth, blurred vision). Tinnitus, confusion, drowsiness, headache, tremor, ataxia, seizures, movement disorders, dyskinesias. Cardiovascular effects, e.g. hypotension, tachycardia, syncope, conduction disturbances, arrhythmias, GI upset, taste disturbance. Blood dyscrasias, sweating, allergic skin reactions, weight changes, testicular swelling, gynaecomastia, changes in blood sugar concentrations, hyponatraemia. Behavioural disturbances. Hepatic impairment, jaundice.
What happens if I miss a dose of Tofranil tablet 25 mg 20×10’s?
Adults: 25 mg three times daily for three days, increasing to 50 mg three or four times daily. Elderly: Initially 10 mg at night, increasing to 10-25 mg three times daily.
Children: Nocturnal enuresis: 6-8 yr, 25 mg at bedtime; 8-11 yr, 25-50 mg at bedtime; 11-18 yr, 50-75 mg at bedtime. Initial period of treatment (including gradual withdrawal) 3 mth, full physical examination before further course.
One of the following licensed pharmacy from the nearest location will deliver Tofranil tablet 25 mg 20×10’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
Questions and Answers
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