₨ 885.09
MBBS
PLATINIL 1mg|ml Injection 100ml vial
Cisplatin:1mg/ml | Cytotoxic (anti-neoplastic) drugs
Alternate brands of PLATINIL 1mg|ml Injection 100ml vial
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Manufactured / Marketed By : Neo Product Form : InjectionPack Size : 100ml VialIngredients : Cisplatin:1mg/mlGeneric Category : Cytotoxic (anti-neoplastic) drugs
How it works
PLATINIL 1mg|ml Injection 100ml vial works by stopping the growth of cancer cells by inhibiting the DNA synthesis.
Side effects
Major & minor side effects for PLATINIL 1mg|ml Injection 100ml vial
- Pain at the injection site severe
- Lower back pain severe
- Fever or chills severe
- Joint pain
- Ringing or buzzing in the ears
- Swelling of feet and lower legs
- Loss of taste
- Convulsions (seizures)
- Sour mouth
Uses of PLATINIL 1mg|ml Injection 100ml vial
What is it prescribed for?
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Testicular Cancer
Cisplatin is used in the treatment of cancer of testicles, which produce the male sex hormones and sperm.
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Ovarian Cancer
Cisplatin is used in the treatment of cancer that affects the ovaries.
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Bladder cancer
Cisplatin is used in the treatment of bladder cancer, which is an organ that stores urine.
Concerns
Frequently asked questions
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Onset of action
The peak effect of this medicine can be observed immediately after intravenous injection.
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Duration of Effect
The effect of this medicine lasts for an average duration of 24 hours.
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Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
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Is it habit forming?
No habit forming tendencies were reported.
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Usage in pregnancy?
This medicine is not recommended for pregnant women.
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Usage while breast-feeding?
This medicine is not recommended in breastfeeding women.
When not to use?
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Allergy
Not recommended in patients with known allergy to Cisplatin or other platinum-containing compounds.
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Impaired kidney function
Not recommended in patients with existing kidney impairment.
Warnings
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Pregnancy
This medicine is not recommended for pregnant women.
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Breast-feeding
This medicine is not recommended in breastfeeding women.
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Impaired kidney function
This medicine may cause severe kidney injury. The risk may increase if taken with aminoglycoside antibiotics. Close monitoring of serum creatinine, urea, and sodium levels is necessary. Do not administer this medicine more than once every 3 to 4 weeks.
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Hearing impairment
This medicine may cause the hearing problem which is more common in children. Audiometric testing should be performed before initiating the treatment and also before every dose. Any symptoms of the hearing problem should be reported to the doctor.
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Allergy
This medicine may cause serious skin reactions. Discontinue the treatment if any symptoms of allergy appear and do not restart.
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Blood cell count
This medicine may lower the white blood cells and platelets. Close monitoring of blood cell count is necessary. Do not start the treatment if the cell count is low.
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Infections
The chances of occurring infections are more in patients receiving this medicine. Hold the chemotherapy and start with the broad-spectrum antibiotics if there are any signs and symptoms of fever. Close monitoring of the body temperature and the blood cell count is necessary.
Dosage
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Missed Dose
It is advised not to miss any dose. If you missed any dose, you should contact your doctor immediately.
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Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
Interactions
Interaction with Medicines- Clozapine severe
- Vancomycin moderate
- Atorvastatin moderate
- Live vaccines severe
General Instructions
This medicine is given in multiple cycles. It is important to receive the every scheduled dose and make a note of next scheduled dose. Close monitoring of blood cells counts and kidney function.
Other details
- Usage does not depend on food timings
- To be taken as instructed by doctor
- May cause sleepiness
References
- practo.com - Cisplatin [Internet]. Available from: https://www.practo.com/medicine-info/cisplatin-63-api [cited 2 october 2019]. 16 Nov 2017
- medlineplus.gov - Cisplatin Injection [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a684036.html [cited 2 october 2019]. 11 September 2019
- dailymed.nlm.nih.gov - CISPLATIN [Internet]. Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b2b029f5-0d7e-4e7f-accc-b722aec34c68#ID36 [cited 2 october 2019]. August 6, 2019
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